An interventional study of Normal sleep and Partial sleep deprivation in Physical Activity, Energy Intake and Appetite, sponsored by National Taiwan Normal University. Not yet recruiting. Open to male participants aged 20 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-02-06.
Sponsored by National Taiwan Normal University · Not applicable, Interventional, and Basic science
This study will investigate whether acute sleep deprivation affects appetite, eating behavior, and physical activity in both regular exercisers and physically inactive individuals.
Prior to the main trials, participants will complete assessments of V̇O2max and maximal muscle strength within 7 to 14 days before the main trials. They will also record one week of daily physical activity, sleep patterns, and diet (including two weekdays and one weekend day) to ensure they meet the inclusion criteria.
Participants will be healthy males aged 20 to 45, grouped according to their habitual activity levels.
Day 1:
Physical activity is restricted to a minimum, with no exercise permitted. Participants are allowed to eat freely before 15:00; however, all food intake will be recorded to enable replication prior to the subsequent main trial. Napping is not permitted. Participants will arrive at the laboratory between 18:30 and 19:00. Subjective appetite sensations and food preferences will be assessed. Participants will have either an 8-hour sleep opportunity in the laboratory from 23:00 to 07:00 (i.e., normal sleep trial) or a 3-hour sleep opportunity from 03:00 to 07:00 (i.e., partial sleep deprivation trial).
Day 2:
Participants will wake at 07:00. After completing personal hygiene, they will rest for 20 minutes to ensure full alertness. At 07:30, a 20-minute resting metabolic rate assessment will be conducted, alongside the collection of heart rate variability and muscle oxygen saturation data. Subsequently, pulse wave velocity measurement, cognitive function tests, subjective questionnaires, and a computerized food preference test will be administered.
After the baseline assessment, a 3-hour oral glucose tolerance test (OGTT) will be administered. Visual analogue scale assessments-including sleep, appetite, and mood-will be conducted every 30 minutes during the OGTT. Food preferences will be measured 180 minutes after the completion of the OGTT. Upon leaving the laboratory, participants will be provided with a pedometer and wearable devices and instructed to record dietary intake (using a food scale and photographic records), sleep, and glucose values on the experimental day and for the following four consecutive days.
2,426 studies on the registry are indexed under Motor Activity; 1,161 are open to participants now.
This study's planned enrollment of 48 is below the median of 60 across 2,118 interventional studies indexed under Motor Activity.
Browse Motor Activity studies →National Taiwan Normal University is the lead sponsor of 62 studies on the registry; 15 are open to participants now.
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Exclusion Criteria:
Participants will have an 8-hour sleep opportunity in the lab from 23:00 to 07:00.
Behavioral: Normal sleep
Participants will have a 3-hour sleep opportunity in the lab from 03:00 to 07:00.
Behavioral: Partial sleep deprivation
Participants will have an 8-hour sleep opportunity in the lab from 23:00 to 07:00.
Participants will have a 3-hour sleep opportunity in the lab from 03:00 to 07:00.
Energy intake
Energy and macronutrients intake will be collected using pictures and via a food scale
Time frame: 4 days in a free-living conditions.
Physical activity
Physical activity level and intensity will be collected using wearable devices
Time frame: 4 days in a free-living conditions.
Food preference
Computerised subjective food choice
Time frame: Baseline and at the end of the 3-hour oral glucose tolerance test (OGTT).
Appetite sensations
Subjective appetitive feelings will be measured using a 0-100 mm visual analog scale (VAS), with higher values indicating more intense feelings.
Time frame: At 0 (baseline), 30, 60, 90, 120, 150, and 180 minutes during the 3-hour oral glucose tolerance test (OGTT).
Mood sensations
Subjective mood feelings will be measured using a 0-100 mm visual analog scale (VAS), with higher values indicating more intense feelings.
Time frame: At 0 (baseline), 30, 60, 90, 120, 150, and 180 minutes during the 3-hour oral glucose tolerance test (OGTT).
Sleep sensations
Subjective sleep feelings will be measured using a 0-100 mm visual analog scale (VAS), with higher values indicating more intense feelings.
Time frame: At 0 (baseline), 30, 60, 90, 120, 150, and 180 minutes during the 3-hour oral glucose tolerance test (OGTT).
Sleep
Sleep duration will be collected via wearable device.
Time frame: 4 days in a free-living conditions.
Glucose responses
Clucose responses will be collected using continuous glucose monitoring
Time frame: 4 days in a free-living conditions.
No study locations are listed for this record.
This study is not yet recruiting, as verified in Feb 2026. You cannot join it, but the record below documents what was studied.
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National Taiwan Normal University