CClinicalTrials.gg
Not yet recruitingNCT07389395Updated Feb 5, 2026

Grastion and Percussion Therapy

An interventional study of Percussion Therapy and Instrument-Assisted Soft Tissue Mobilization (AISM) in Muscle Fatigue and Muscle Oxygenation, sponsored by Karabuk University. Not yet recruiting. Open to participants aged 18 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-02-05.

Sponsored by Karabuk University · Not applicable, Interventional, and Other

From the registry’s dates

  • Primary completion was expected by Apr 2026, 6 months ago, but the record still lists the study as not yet recruiting.
Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Randomized
Ages
18 Years to 35 Years
Sex
All
01

Study summary

The study aims to investigate the effects of percussion therapy and instrument-assisted soft tissue mobilization (AISM), commonly used in clinical settings, on muscle fatigue, maximum muscle strength, pain threshold, and muscle oxygenation.

The study will involve 20 volunteer participants. To achieve the study results, pre-exercise percussion therapy and instrument-assisted soft tissue mobilization (AISM) will be administered using a crossover design.

Results will be measured using a digital dynamometer, a moxy oxygen monitor, and a fatigue questionnaire.

02

Conditions studied

  • Muscle Fatigue and Muscle Oxygenation

Keywords

  • Muscle Oxygen Saturation
  • Muscle Strength
  • Instrument-Assisted Soft Tissue Mobilization (Graston Technique)
  • Percussion Therapy
03

In context

Lead sponsor

Karabuk University is the lead sponsor of 126 studies on the registry; 30 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 35 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Aged 18-35 years
  • Healthy participants
  • Sedentary lifestyle as defined by the International Physical Activity Questionnaire (IPAQ) (low physical activity category)
  • Ability to understand the study procedures and provide written informed consent

Exclusion criteria

Exclusion Criteria:

  • Upper extremity injury or surgery within the past 6 months
  • Presence of skin lesions, wounds, or dermatological diseases at the application site
  • Any diagnosed musculoskeletal disorder
  • History of cardiovascular, metabolic, or pulmonary disease
  • Presence of neurological disorders or cognitive impairment affecting cooperation
  • Use of medications affecting neuromuscular function or circulation
  • Participation in any upper extremity strength training within the past 3 months
  • Contraindications to percussion therapy or instrument-assisted soft tissue mobilization (Graston)
05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Randomized
Intervention model
Crossover assignment
Masking
Single (Investigator)
Enrollment
20 participants (estimated)

Study arms

  • Active comparator
    instrument-assisted soft tissue mobilization

    With the Graston method, 2 minutes of soft tissue mobilization will be performed on the biceps muscle before the exercise.

    Other: Instrument-Assisted Soft Tissue Mobilization (AISM)

  • Active comparator
    percussion gun

    A percussion gun will be applied to the biceps muscle for 2 minutes before the exercise.

    Other: Percussion Therapy

  • No intervention
    control

    A 2-minute warm-up will be performed without any application.

Interventions

  • OtherPercussion Therapy

    The massage gun will operate at a frequency of 30 beats per second (30 Hz), and percussion therapy will be applied to the muscle for 2 minutes. Percussion therapy will be performed using the device's standard ball head. The force applied by the device will be fixed so that it does not exceed the device's first-stage force setting (approximately 30 pounds). The biceps brachii (dominant arm) will be treated for 2 minutes at 30 Hz, moderate intensity.

  • OtherInstrument-Assisted Soft Tissue Mobilization (AISM)

    The arm will be positioned at the edge of the bed in full extension, with the shoulder in 45-degree abduction. The examiner will apply gentle pressure using a 30-degree angled instrument at a rate of 120 strokes/min, aligning the instrument's weight with the fibers of the biceps brachii muscle. The examiner will use a metronome to maintain a consistent pace during treatment, and the instrument angle will be calibrated with a protractor before each subject's treatment. The procedure will last 2 minutes, and baby oil will be used to ensure the instrument moves smoothly over the skin.

06

What researchers measure

Primary outcomes

  1. Muscle Oxygen Saturation (SmO₂)

    Oxygen saturation will be measured with the MOXY device. It is an infrared measuring device called "near infrared spectroscopy" that measures oxygen saturation and total hemoglobin in muscle capillaries. The device will be attached to the highest point of the muscle and secured with a black sheath and tape to prevent light exposure.

    Time frame: "Baseline (30 seconds before exercise)" "During the entire exercise period (from exercise onset to exercise termination)" "Post-exercise (0 to 2 minutes after exercise termination)"

Secondary outcomes

  1. Muscle Strength

    Subjects will be seated with the elbow joint flexed to 90°, forearm in supination. They will be asked to contract their muscles in the direction of elbow flexion for 5 seconds, and the physiotherapist will apply force in the opposite direction to prevent movement in the elbow joint. Three measurements will be taken 30 seconds apart, and the average will be recorded.

    Time frame: "30, 60, and 90 seconds before the warm-up or intervention" "30, 60, and 90 seconds after the warm-up or intervention" "30, 60, and 90 seconds after exercise"

Other outcomes

  1. Pain Threshold

    Measurements will be taken at the same point for all participants while the subjects lie supine, with the forearm in full supination at the side of the body and the elbow in full extension. A control trial will be conducted before the measurement, and participants will be instructed to say "OK" as soon as they feel pain

    Time frame: "120 seconds before the warm-up or intervention" "120 seconds after the warm-up or intervention" "120 seconds after exercise"

  2. Perceived Fatigue

    This is a scale used to assess the degree of exertion felt by the participant after exercise. The Borg Scale allows the participant to express the fatigue felt during exercise on a scale of none (6), very light (7-8), light (9-10), fairly light (11-12), somewhat difficult (13-14), difficult (15-16), very difficult (17-18), very very difficult (19), and exhaustion (20)

    Time frame: "Baseline (180 seconds before exercise)" "Post-exercise, immediate (0 minutes)" "Post-exercise (24 hours after exercise termination)" "Post-exercise (48 hours after exercise termination)" "Post-exercise (72 hours after exercise termination)"

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 5, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07389395
Lead sponsor
Karabuk University
Responsible party
METEHAN YANA (Assistant Professor, Karabuk University) — Principal investigator
First posted
Feb 5, 2026
Start date
Feb 15, 2026 (estimated)
Primary completion
Apr 1, 2026 (estimated)
Completion
Jun 15, 2026 (estimated)
Last update
Feb 5, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Jan 2026. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion