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CompletedNCT07373197Updated Jan 28, 2026

Lateral Rectus Muscle Strangulation in Cases of Exotropia

An interventional study of Muscle strangulation in Strabismus, Divergent, sponsored by Sohag University. Completed at 1 site in Egypt. Open to participants aged 15 Years to 50 Years. Per ClinicalTrials.gov, last updated 2026-01-28.

Sponsored by Sohag University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 1 year 8 months after the study started (first participant enrolled Jan 2024, registered Sep 2025).
Phase
Not applicable
Study type
Interventional
Enrollment
12
Allocation
Not applicable
Ages
15 Years to 50 Years
Sex
All
01

Study summary

The goal of our study to evaluate effect of lateral rectus muscle strangulation as a novel effective weakening technique in cases of exotropia.

It is a case-series intervensional study with a total 12 participant who are diagnosed as exophoria or intermittent exotropia who are older than 4 years old.

All patients will be assessed regarding their angle of deviation and then undergo lateral rectus muscle strangulation under general anesthesia and then will be followed- up at 1st day, 1st week, 1st month and 6th months.

Read the detailed description

Under general anesthesia and after sterilization and draping of the eyes, an eye speculum is inserted. The muscle is exposed and hooked through either a fornix-based or limbal-based incision. Careful dissection is carried out to delineate the muscle edge, a previously measured blook of the lateral rectus muscle is sutured (strangulated) with proline 10/0 as in (fig-1). Patients will be followed-up next day after surgery then after 1 month and after 6 months.

02

Conditions studied

  • Strabismus, Divergent

Browse trials for

Keywords

  • Exotropia
  • Lateral rectus muscle
03

In context

Exotropia

58 studies on the registry are indexed under Exotropia; 13 are open to participants now.

This study's enrollment of 12 is below the median of 50 across 49 interventional studies indexed under Exotropia.

Browse Exotropia studies →

Lead sponsor

Sohag University is the lead sponsor of 1,230 studies on the registry; 636 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
15 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • intermittent exotropia

Exclusion criteria

Exclusion Criteria:

  • previous squint surgery
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
12 participants (actual)

Study arms

  • Experimental
    lateral rectus muscle strangulation

    lateral rectus muscle strangulation as a weakening technique in cases of exotropia.

    Procedure: Muscle strangulation

Interventions

  • ProcedureMuscle strangulation

    lateral rectus muscle strangulation as a weakening technique in cases of exotropia.

06

What researchers measure

Primary outcomes

  1. Correction of strabismus

    the correction was done by lateral rectus muscle strangulation

    Time frame: 12 months

Secondary outcomes

  1. orthophoria

    to make both eyes aligned together, and to maintain orthophoria

    Time frame: 12 months

07

Study locations

1 site
  • Sohag University
    Sohag, Egypt
08

References and documents

Publications

  • Rageh MA, Awadein A, Arfeen SA. Extraocular muscle fenestration: a novel weakening procedure. Can J Ophthalmol. 2020 Oct;55(5):455-457. doi: 10.1016/j.jcjo.2020.05.018. Epub 2020 Aug 26. No abstract available. PubMed 32860744 ↗
  • Taher SG, Rageh MA, Hashem O. Extra Ocular Muscle Fenestration as a Weakening Maneuver for Surgical Management of Strabismus: A Randomized Pilot Clinical Trial. Clin Ophthalmol. 2022 Jan 8;16:63-70. doi: 10.2147/OPTH.S347092. eCollection 2022. PubMed 35035214 ↗
  • Koc F, Ozal H, Yasar H, Firat E. Resolution in partially accomodative esotropia during occlusion treatment for amblyopia. Eye (Lond). 2006 Mar;20(3):325-8. doi: 10.1038/sj.eye.6701874. PubMed 15933753 ↗

Related links

Study documents

PDFs hosted by the registry, ClinicalTrials.gov.

Individual participant data

Plan to share: Undecided — we havenot decided until now to share IPD with other researchers

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 28, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07373197
Lead sponsor
Sohag University
Responsible party
Amr Mounir (Assistant Professor, Sohag University) — Principal investigator
First posted
Jan 28, 2026
Start date
Jan 1, 2024
Primary completion
Jul 1, 2024
Completion
Feb 2, 2025
Last update
Jan 28, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2025. You cannot join it, but the record below documents what was studied.

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