A Phase 3 interventional study of Hyaluoric acid mouthwash and Chlorhexidine 0,12% in Gingivitis; Chronic, sponsored by Cairo University. Completed at 1 site in Egypt. Open to participants aged 25 Years and older. Per ClinicalTrials.gov, last updated 2026-01-26.
Sponsored by Cairo University · Phase 3, Interventional, and Treatment
Patients were instructed to use 2 different mouthwashes after performing professional tooth cleaning. The effect of each of the 2 mouthwashes was detected.
The study tests the efficacy of hyaluronic acid (HYL) mouthwash as adjunct to Chlorhexidine (CHX) mouthwash compared to Chlorhexidine mouthwash only in 16 gingivitis patients. Patients were randomly assigned to either control group received (Chlorhexidine mouthwash) or test group received (hyaluronic acid + Chlorhexidine mouthwash). Clinical parameters and patient reported outcomes as post-operative questionnaire were assessed at baseline and seven days post-operatively.
590 studies on the registry are indexed under Gingivitis; 105 are open to participants now.
This study's enrollment of 16 is below the median of 64 across 478 interventional studies indexed under Gingivitis.
Browse Gingivitis studies →Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.
Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Drug: Chlorhexidine 0,12%
Drug: Hyaluoric acid mouthwash · Drug: Chlorhexidine 0,12%
A mouthwash containing both hyaluronic acid
mouthwash of chlorhexidine 0.12%
Bleeding on probing
% of gingival sites where bleeding occurred on periodontal probing is registered out of total gingival sites
Time frame: 7 days
Plaque index
% of gingival sites where plaque accumulates is registered out of total gingival sites
Time frame: 7 days
Patient's satisfaction questionnaire
Time frame: 7 days
This study is completed, as verified in Jan 2026. You cannot join it, but the record below documents what was studied.
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Cairo University