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Not yet recruitingNCT07351552Updated Jan 20, 2026

The Effect of Frailty on Hypotension After Anesthesia Induction

An observational study in Fraility and Hypotension, sponsored by Selcuk University. Not yet recruiting. Open to participants aged 65 Years and older. Per ClinicalTrials.gov, last updated 2026-01-20.

Sponsored by Selcuk University · Observational

From the registry’s dates

  • Primary completion was expected by Apr 2026, 5 months ago, but the record still lists the study as not yet recruiting.
Study type
Observational
Model
Case-crossover
Time perspective
Prospective
Enrollment
80
Ages
65 Years and older
Sex
All
01

Study summary

Frailty is defined as a state of weakness resulting from a decrease in physiological reserves due to physiological changes, diseases, and/or malnutrition associated with advancing age. Frail older adults face increased mortality, morbidity, and healthcare costs when exposed to stressors, making this issue increasingly important. The FRAIL Scale, developed by Morley et al. , is a 5-item measure that assesses frailty. The FRAIL Scale has been validated in many countries and has been proven to be an effective method for detecting frailty. This scale assesses the patient's fatigue, resistance, mobility, weight loss, and other diseases. In the 5-item FRAIL scale, patients receive 0 or 1 point based on their answers, and a total of 0 points is considered non-frail, 1-2 points is considered pre-frail, and >2 points is considered frail.

Frailty is associated with a higher risk of postoperative complications. Rothenberg and colleagues reported in a study involving more than 400,000 patients that frailty doubles the risk of postoperative complications .

Hypotension following anesthesia induction is a common complication in geriatric patients. Decreased cardiopulmonary reserve with age leads to an exaggerated drop in blood pressure during induction .

In this study, the investigators aimed to determine the effect of frailty level in geriatric patients on hypotension observed after anesthesia induction.

02

Conditions studied

  • Fraility
  • Hypotension

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03

In context

Hypotension

1,003 studies on the registry are indexed under Hypotension; 173 are open to participants now.

This study's planned enrollment of 80 is close to the median of 84 across 294 observational studies indexed under Hypotension.

Browse Hypotension studies →

Lead sponsor

Selcuk University is the lead sponsor of 248 studies on the registry; 63 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
65 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Patients over the age of 65 undergoing elective surgery under general anesthesia

Inclusion criteria

  • Patients who do not have difficulty communicating,
  • have good cognitive function,
  • scheduled for surgery under general anesthesia

Exclusion criteria

Exclusion Criteria:

  • Patients admitted for surgery in emergency situations
  • Patients with active malignancy
  • Patients with physical disabilities and impairments (limb amputations, stroke sequelae, unable to speak, hearing problems)
  • Patients with acute infections
  • Patients with acute illnesses (decompensated congestive heart failure, recent myocardial infarction/stroke, COPD exacerbation)
  • Patients who have been hospitalized or undergone surgery within the last month
  • Patients with advanced dementia
  • Patients who are unable to provide a medical history or cooperate
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Study design

Observational model
Case-crossover
Time perspective
Prospective
Enrollment
80 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. The effect of fragility level on hypotension observed after anesthesia induction

    Time frame: 20 minutes

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Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 20, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07351552
Lead sponsor
Selcuk University
Responsible party
EMİNE ASLANLAR (associated professor, Selcuk University) — Principal investigator
First posted
Jan 20, 2026
Start date
Jan 15, 2026 (estimated)
Primary completion
Apr 15, 2026 (estimated)
Completion
Jun 15, 2026 (estimated)
Last update
Jan 20, 2026

Study contacts

Emine ASLANLAR
Contact
draslanlar@gmail.com
05556219830

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Oct 2025. You cannot join it, but the record below documents what was studied.

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