An interventional study of Special diet plan and whole protein preparation NUTRICIA for 5 days after liver resection for liver cancer and Conventional dietary intervention in Primary Liver Cancer, sponsored by Anhui Provincial Hospital. Completed at 1 site in China. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2026-01-20.
Sponsored by Anhui Provincial Hospital · Not applicable, Interventional, and Supportive care
Objective:To explore the application effect of postoperative refined early dietary plan in the enhanced recovery of patients undergoing hepatectomy for primary liver cancer, and to provide scientific evidence for optimizing postoperative dietary structure and increasing oral energy intake of patients.
Methods:In this randomized, parallel-controlled trial, 142 colorectal cancer survivors meeting inclusion criteria were recruited from a tertiary hospital in Hefei, Anhui Province. Participants were randomly assigned in a 1:1 ratio to either the dietary intervention group or the conventional diet group. Both the standard care group and the dietary intervention group received 5 days of routine dietary care. The dietary intervention group additionally received specialized meal plans and whole protein supplements beyond the standard care regimen. Dietary intake, nutritional status, and postoperative recovery outcomes were measured and compared between the two groups.
3,180 studies on the registry are indexed under Carcinoma, Hepatocellular; 953 are open to participants now.
This study's enrollment of 139 is above the median of 55 across 2,298 interventional studies indexed under Carcinoma, Hepatocellular.
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Exclusion Criteria:
Dietary Supplement: Special diet plan and whole protein preparation NUTRICIA for 5 days after liver resection for liver cancer
Other: Conventional dietary intervention
The intervention group, based on the control group, followed the "Chinese Clinical Practice Guidelines for Enhanced Recovery After Surgery (Part II)"and evidence-based summaries, combined with the "Chinese Expert Consensus on Perioperative Management for Hepatectomy in Hepatocellular Carcinoma (2021 Edition)" and oral nutritional supplementation guidelines, Based on the patient's comorbidities, liver characteristics, and gastrointestinal recovery patterns, a specialized 5-day post-hepatectomy diet plan for liver cancer patients has been developed. Postoperatively, oral nutritional supplements (ONS) were administered at 9:30 AM and 3:00 PM between meals, and at 9:00 PM after dinner, using the whole protein preparation NUTRICIA(specification: 320g/can, manufacturer: Milupa GmbH, Germany, production batch: HJ20170172).
After returning to the ward after the operation under the traditional dietary guidance model, the patient regained consciousness under anesthesia without nausea, vomiting, etc., and began to try drinking water. If there are no special conditions such as gastrointestinal discomfort, then starting according to the dietary principles, that is, a liquid diet on the first day after the operation, a semi-liquid diet on the second day, and gradually transitioning to a regular diet from the third day after the operation until discharge based on the patient's tolerance. One to two days after the operation, parenteral nutrition mixtures are routinely infused.
Prealbumin
Time frame: Six days after the operation
albumin
Time frame: Six days after the operation
Plan to share: Undecided
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This study is completed, as verified in Jan 2026. You cannot join it, but the record below documents what was studied.
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Anhui Provincial Hospital