An interventional study of Blood flow restriction resistance exercise in Cardiac, sponsored by Montclair State University. Not yet recruiting at 1 site in United States. Open to participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-02-13.
Sponsored by Montclair State University · Not applicable, Interventional, and Other
Blood flow restriction resistance exercise uses partial vascular occlusion of a limb during low weight resistance exercises to stimulate muscle strengthening and growth. This is commonly used during rehabilitation from an injury. Because blood flow in and out of the limbs is decreased, this may have consequences for blood flow through the heart. The purpose of this study will be to test cardiac dynamics during blood flow restriction resistance exercise to determine if cardiac blood flow is impacted. It is hypothesized that both non-BFR exercise and BFR exercise will increase heart rate shortening various cardiac cycle parameters, but BFR exercise will increase the isovolumetric contraction time vs non-BFR exercise due to an increase in total peripheral resistance. It is also hypothesized that BFR exercise will lower early ventricular filling parameters due to lower venous return.
Montclair State University is the lead sponsor of 13 studies on the registry; 6 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Blood flow restriction resistance exercise
Behavioral: Blood flow restriction resistance exercise
Blood flow in and out of the limb will be artificially with an occlusion cuff.
Cardiac cycle durations
Time frame: During the intervention for approximately 10 minutes.
Ventricular filling
Time frame: During intervention phase for approximately 10 minutes.
Plan to share: No
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This study is not yet recruiting, as verified in Feb 2026. You cannot join it, but the record below documents what was studied.
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Montclair State University