An observational study in Overweight and Obesity, sponsored by Montclair State University. Enrolling by invitation at 1 site in United States. Open to participants aged 18 Years to 50 Years. Per ClinicalTrials.gov, last updated 2025-01-31.
Sponsored by Montclair State University · Observational
This investigations examined the effect that posture has on metabolic and cardiovascular measurements. Further, it will explore the potential for body weight status or physical activity to influence these relationships. All subjects will complete a seated condition and a standing condition in a counterbalanced manner.
The purpose of the present study was to evaluate both metabolic and cardiovascular responses to acute bouts of computer work while sitting and standing. Cardiovascular measurements were made using continuous non-invasive blood pressure monitoring and metabolic measurements were made using indirect calorimetry. Subjects will be grouped and analyzed based upon the weight status of the subject. All subjects will complete a seated condition and a standing condition in a counterbalanced manner. Investigators hypothesize that metabolic and cardiovascular responses will be elevated in the standing condition compared to sitting.
3,670 studies on the registry are indexed under Overweight; 849 are open to participants now.
This study's planned enrollment of 80 is below the median of 150 across 436 observational studies indexed under Overweight.
Browse Overweight studies →Montclair State University is the lead sponsor of 13 studies on the registry; 6 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Healthy subjects between the ages of 18 and 50 years.
Exclusion Criteria:
Group is determined based upon subjects weight status. Subjects will preform computer work in the seated and standing position in a counterbalanced manner while metabolic and cardiovascular measurements are made.
Behavioral: sit/stand
Group is determined based upon subjects weight status. Subjects will preform computer work in the seated and standing position in a counterbalanced manner while metabolic and cardiovascular measurements are made.
Behavioral: sit/stand
Subjects will be asked to both sit and stand during a single trial.
Heart Rate
Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be used to measure heart rate based upon beat-by-beat finger pressure.
Time frame: Approximately 15 minutes in each condition (sitting and standing)
Systolic Blood Pressure (SBP)
Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be used to measure SBP based upon beat-by-beat finger pressure.
Time frame: Approximately 15 minutes in each condition (sitting and standing)
Diastolic Blood Pressure (DBP)
Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be used to measure DBP based upon beat-by-beat finger pressure.
Time frame: Approximately 15 minutes in each condition (sitting and standing)
Oxygen Consumption
Oxygen consumption will be measured using indirect calorimetry.
Time frame: Approximately 15 minutes in each condition (sitting and standing)
Carbon Dioxide Production
Carbon Dioxide will be measured using indirect calorimetry.
Time frame: Approximately 15 minutes in each condition (sitting and standing)
Ventilation
Ventilation will be measured using indirect calorimetry.
Time frame: Approximately 15 minutes in each condition (sitting and standing)
Respiratory Exchange Ration (RER)
RER will be calculated using oxygen and carbon dioxide value measure from indirect calorimetry.
Time frame: Approximately 15 minutes in each condition (sitting and standing)
Height
Standard stadiometer will be used to measure height in meters.
Time frame: 1 minute
Weight
Standard scale will be used to measure weight in kilograms.
Time frame: 1 minute
Body Mass Index (BMI)
Height in meters and weight in kilograms will be used to calculate BMI using the formula BMI = kg/m\^2.
Time frame: 1 minute
Body Composition
Body composition will be measured using air displacement plethysmography.
Time frame: Approximately 15 minutes
Total Peripheral Resistance (TPR)
Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be uses to estimate TPR based upon beat-by-beat finger pressure.
Time frame: Approximately 15 minutes in each condition (sitting and standing)
Stroke Volume
Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be used to estimate TPR based upon beat-by-beat finger pressure.
Time frame: Approximately 15 minutes in each condition (sitting and standing)
Cardiac Output (Q)
Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be used to estimate Q based upon beat-by-beat finger pressure.
Time frame: Approximately 15 minutes in each condition (sitting and standing)
Muscle Oxygen Saturation
Using Near-inferred spectroscopy muscle oxygen consumption will be monitored.
Time frame: Approximately 15 minutes in each condition (sitting and standing)
Plan to share: No
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Montclair State University