CClinicalTrials.gg
CompletedNCT07344545Updated Jan 15, 2026

Mining the Gut Microbiota of Adults for Health-relevant Microbial Signatures.

An observational study in Adult, sponsored by Zhujiang Hospital. Completed at 1 site in China. Open to participants aged 30 Years to 95 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-01-15.

Sponsored by Zhujiang Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
1,530
Ages
30 Years to 95 Years
Sex
All
01

Study summary

Mining the gut microbiota of adults for health-relevant microbial signatures.

Read the detailed description

This study is a community-based, observational cross-sectional investigation, enrolling 1,530 middle-aged and elderly volunteers.

Data were collected through a systematic, multi-dimensional assessment, which included:

Biospecimen Collection: Blood, urine, and stool samples were obtained from the volunteers.

Physical and Imaging Examinations: Procedures included anthropometric measurements, vital sign monitoring, oral examinations, electrocardiograms, physical examinations of key organs, and abdominal ultrasonography.

Psychological and Cognitive Assessments: Standardized scales were administered to assess anxiety/depression and memory function.

All clinical and questionnaire data were processed through standardized procedures, forming a comprehensive health database for subsequent analysis.

02

Conditions studied

  • Adult
03

In context

Lead sponsor

Zhujiang Hospital is the lead sponsor of 199 studies on the registry; 96 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
30 Years to 95 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Meet eligibility criteria

Inclusion criteria

  • Community-dwelling adults aged 30 to 95 years.
  • Individuals who underwent an annual health examination at the Health Management Center of Huzhou Central Hospital during the specified time period.
  • Ability to comprehend the study content and voluntarily provide signed informed consent.
  • Willingness and ability to provide the required biospecimens (blood, urine, stool).

Exclusion criteria

Exclusion Criteria:

  • Concurrent participation in another interventional clinical trial that is likely to interfere with the results of this study.
  • Voluntary withdrawal from the study.
05

Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
1,530 participants (actual)
Patient registry
No

Groups and cohorts

  • adult volunteers

    The study population consists of 1,530 middle-aged and elderly volunteers from the same community who underwent comprehensive health examinations at Huzhou Central Hospital . All participants completed a multi-dimensional assessment including biospecimen collection, physical/imaging examinations, and psychometric evaluations.

    Other: Observational, non-interventional study.

Interventions

  • OtherObservational, non-interventional study.

    Observational, non-interventional study.

06

What researchers measure

Primary outcomes

  1. Identification of Health-Relevant Signatures in Adults

    Primary Outcome Measure 1)Change in standard laboratory parameters from baseline:Changes in routine laboratory parameters measured in blood, urine, and stool samples, including complete blood count and standard serum biochemistry panels.Unit of Measure: Various laboratory units (e.g., g/L, U/L, mmol/L); 2) Change in anthropometric measurements from baseline: Anthropometric measurements including body weight (kg), height (m), and body mass index (BMI, kg/m²).Unit of Measure:kg, m, kg/m²; 3) Alcohol consumption status: Alcohol consumption status assessed by self- report, categorized as current drinker or non-drinker at enrollment.Unit of Measure:Categorical (yes/no); 4) Hospital Anxiety and Depression Scale (HADS) scores: Anxiety and depression symptom severity assessed using the Hospital Anxiety and Depression Scale, including anxiety and depression subscale scores.Unit of Measure:Score on a standardized scale.

    Time frame: Baseline

07

Study locations

1 site
  • Zhujiang Hospital of Southern Medical University
    Guangzhou, Guangdong 510000, China
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 15, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07344545
Lead sponsor
Zhujiang Hospital
Collaborators
Huzhou Central Hospital
Responsible party
Xiaolong He (Department of Laboratory Medicine, Zhujiang Hospital) — Principal investigator
First posted
Jan 15, 2026
Start date
Aug 15, 2021
Primary completion
Aug 30, 2021
Completion
Sep 29, 2021
Last update
Jan 15, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2025. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion