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RecruitingNCT07334314OUAFUpdated Jan 12, 2026

Olfactive Detection of Urothelial Carcinoma by Sniffer Dogs

An observational study in Urothelial Carcinoma, sponsored by University Hospital, Strasbourg, France. Recruiting at 2 sites in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-01-12.

Sponsored by University Hospital, Strasbourg, France · Observational

From the registry’s dates

  • Started Jun 2025; still recruiting 1 year 3 months later.
Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
340
Ages
18 Years and older
Sex
All
01

Study summary

The aim of this study is to estimate the sensitivity of olfactory detection of urothelial carcinomas of the bladder in urine samples by assistance dogs trained in this practice.

02

Conditions studied

  • Urothelial Carcinoma
03

In context

Carcinoma, Transitional Cell

716 studies on the registry are indexed under Carcinoma, Transitional Cell; 201 are open to participants now.

This study's planned enrollment of 340 is above the median of 200 across 123 observational studies indexed under Carcinoma, Transitional Cell.

Browse Carcinoma, Transitional Cell studies →

Lead sponsor

University Hospital, Strasbourg, France is the lead sponsor of 966 studies on the registry; 342 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Subject scheduled for any endourological surgery involving an initial cystoscopy, the most common of which are: transurethral resection of the bladder, transurethral resection of the prostate, internal optical urethrotomy, bladder lithoclast, ureteral stent replacement, ureteroscopy, etc. (non-exhaustive list).

Recruitment will take place in the urology department, during the preoperative consultation or during hospitalization.

Inclusion criteria

  • Adult (> 18 years old)
  • Subject scheduled for any endourological surgery involving an initial cystoscopy, the most common of which are: transurethral resection of the bladder, transurethral resection of the prostate, internal optical urethrotomy, bladder lithoclast, ureteral stent replacement, ureteroscopy, etc. (non-exhaustive list)
  • Subjects for whom a urine sample (for bacteriological or cytological testing) is planned as part of routine practice in the month prior to the procedure
  • Subjects affiliated with a health insurance plan or beneficiaries of such a plan

Exclusion criteria

Exclusion Criteria:

  • Absence of signed informed consent / inability to provide the subject with informed information (emergency situations, difficulties in understanding the subject, etc.)
  • Patient under guardianship, conservatorship, or judicial protection
  • History of cancer other than urothelial bladder carcinoma, unless in complete remission for > 5 years
  • Pregnant or breastfeeding women
05

Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
340 participants (estimated)
Patient registry
No

Groups and cohorts

  • Positive bladder tumor

    Bladder tumor present during cystoscopy and confirmed by pathological examination.

    Diagnostic Test: olfactory detection by dogs

  • Negative bladder tumor

    No bladder tumor on cystoscopy/suspicious lesion but with negative pathological analysis

    Diagnostic Test: olfactory detection by dogs

Interventions

  • Diagnostic testolfactory detection by dogs

    olfactory detection of urothelial carcinoma of the bladder in a urine sample by dogs

06

What researchers measure

Primary outcomes

  1. Assess the sensitivity of olfactory detection of urothelial carcinomas of the bladder in urine samples by assistance dogs trained for this purpose

    Time frame: Day -60 to Day 0

07

Study locations

2 of 2 sites recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 12, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07334314
Lead sponsor
University Hospital, Strasbourg, France
Responsible party
Sponsor
First posted
Jan 12, 2026
Start date
Jun 20, 2025
Primary completion
Sep 2026 (estimated)
Completion
Sep 2026 (estimated)
Last update
Jan 12, 2026

Study contacts

Victor GAILLARD
Contact
victor.gaillard@chru-strasbourg.fr
+33 3 69 55 10 55

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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