Carcinoma, Transitional Cell clinical trials
The registry lists 633 studies for Carcinoma, Transitional Cell across more than 10 countries. 181 are recruiting or about to start. 337 of them are mainly about Carcinoma, Transitional Cell (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
ClinicalTrials.gov finds 1,163 studies for Carcinoma, Transitional Cell. How that becomes 633 here
This page counts the studies the registry files under Carcinoma, Transitional Cell, and those it files under no condition that list Carcinoma, Transitional Cellthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 1,163Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −56List Carcinoma, Transitional Cell as a condition, but the registry did not file them under itMost often written as “Transitional Cell Carcinoma of the Bladder” (24), “Fallopian Tube Transitional Cell Carcinoma” (20), and “Ovarian Transitional Cell Carcinoma” (17). The registry filed them under other conditions only, most often Urinary Bladder Neoplasms (27) and Fallopian Tube Neoplasms (18).
- −474Match it another way54 name it in the title, 60 in a keyword, and 360 by a synonym or other text the search reads.
- 633The count on this page12 of them list Carcinoma, Transitional Cell in their own words; the registry filed them under no condition.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
National Cancer Institute (NCI) (25) · M.D. Anderson Cancer Center (14) · Memorial Sloan Kettering Cancer Center (12) · Pfizer (11) · UroGen Pharma Ltd. (10) · Fox Chase Cancer Center (9) · National Taiwan University Hospital (9) · Hoffmann-La Roche (8)
What is being tested here
Drugs under test in Carcinoma, Transitional Cell studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Enfortumab vedotin | 10 | 1 | 20 |
| Pembrolizumab | 8 | 3 | 27 |
| Disitamab vedotin | 5 | 2 | 10 |
| Nivolumab | 4 | 1 | 16 |
| Avelumab | 4 | 3 | 14 |
| Sacituzumab govitecan | 4 | 1 | 9 |
| Gemcitabine | 3 | 3 | 26 |
| Toripalimab | 3 | 2 | 7 |
| Gallium-68 | 3 | 1 | 3 |
| Mitomycin | 2 | 6 | 11 |
Drug classes tested here Immune checkpoint inhibitors 30 open · Antibody-drug conjugates (ADCs) 22 open · Tyrosine kinase inhibitors (TKIs) 8 open · Antimetabolites 5 open · Alkylating agents 3 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026A Study of Adjuvant Cretostimogene Grenadenorepvec for Treatment of Intermediate Risk NMIBC Following TURBT · Phase 3 · CG Oncology, Inc.
- Nov 2026Avelumab Program Rollover Study · Phase 3 · EMD Serono Research & Development Institute, Inc.
- Dec 2026BCG + MMC: Adding Mitomycin C to BCG in High-risk, Non-muscle-invasive Bladder Cancer · Phase 3 · Nottingham University Hospitals NHS Trust
- Dec 2026A Study of RC48-ADC Combined With Toripalimab For First-line Treatment of Urothelial Carcinoma · Phase 3 · RemeGen Co., Ltd.
- Jan 2027Disitamab Vedotin With Pembrolizumab vs Chemotherapy in Previously Untreated Urothelial Cancer Expressing HER2 · Phase 3 · Seagen, a wholly owned subsidiary of Pfizer
- Mar 2027A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer · Phase 3 · UroGen Pharma Ltd.
- Jun 2027A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With Recurrent or Metastatic Urothelial Carcinoma(PANKU-Bladder01) · Phase 3 · Sichuan Baili Pharmaceutical Co., Ltd.
- Jun 2027Study of Tislelizumab in Combination With Chemotherapy Compared to Chemotherapy Alone for Participants With Urothelial Carcinoma · Phase 3 · BeiGene
- Sep 20279MW2821 in Combination With Toripalimab vs Standard Chemotherapy in Locally Advanced or Metastatic Urothelial Cancer · Phase 3 · Mabwell (Shanghai) Bioscience Co., Ltd.
- Nov 2026Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations · Tyra Biosciences, Inc
Who these studies take
Of the 147 Carcinoma, Transitional Cell studies recruiting now, 121 (82%) set no upper age limit and 11 (7%) stop at 75 or younger. 4 (3%) take children under 18. 2 (1%) are for women only and 1 (1%) for men only; 8 (5%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (2%) | 3 (2%) |
| 18 | 139 (95%) | 137 (93%) |
| 30 | 142 (97%) | 141 (96%) |
| 40 | 143 (97%) | 142 (97%) |
| 50 | 145 (99%) | 144 (98%) |
| 65 | 146 (99%) | 145 (99%) |
| 75 | 144 (98%) | 143 (97%) |
| 85 | 129 (88%) | 128 (87%) |
Across all 633 studies, recruiting or not: 5% stop at 75 or younger and <1% at 65; 4% take children; 1% are for women only and <1% for men only; 3% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Carcinoma, Transitional Cell studies take
Of 119 phase 2 interventional studies under Carcinoma, Transitional Cell, half reached primary completion within 57 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 44 mo31–63 · 99 studies | 44 mo34–57 · 62 studies | 48 mo26–73 · 37 studies |
| Phase 1/2 | 64 mo49–224 · 48 studies | — | — |
| Phase 2 | 57 mo35–102 · 119 studies | — | 59 mo40–102 · 91 studies |
| Phase 3 | 56 mo24–111 · 28 studies | — | — |
| Interventional, no phase | 58 mo23–… · 28 studies | — | — |
| Observational | 56 mo27–… · 60 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting2
Results posted3
- Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign DiseaseNov 5, 2026NCT01552434
- PRO1107 in Patients With Advanced Solid TumorsOct 29, 2026NCT06171789
- A Study of E7130 in Participants With Solid TumorsOct 23, 2026NCT03444701
Stopped1
- A Study of E7130 in Participants With Solid TumorsTerminatedOct 23, 2026NCT03444701
Newly registered3
- Risk-Enabled Therapy After Initiating EV/Pembro for Bladder CancerNov 2, 2026NCT07908979
- A Real-world Study to Learn About of the Characteristics and Outcomes of Advanced or Metastatic Bladder Cancer Patients With Different HistologiesOct 27, 2026NCT07897669
- Urinary Cell-Free DNA Liquid Biopsy for Urothelial Cancer Diagnosis and Origin IdentificationOct 22, 2026NCT07888374
Studies
Recruiting first, then most recently updated. Showing 50 of 633. Browse all 633 → or search them.
- Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)RecruitingNCT04198766Phase 1/24 countries
- Registry Platform Urologic CancerRecruitingNCT033742671 country
- A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid TumorsRecruitingNCT07090499Phase 16 countries
- A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial CancerRecruitingNCT06524544Phase 31 country
- A Phase 2 Study of Zanidatamab in Patients With HER2-expressing TumorsRecruitingNCT06695845Phase 24 countries
- Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary TumorsRecruitingNCT03866382Phase 22 countries
- A Study of GEN1106 in Participants With Solid TumorsRecruitingNCT07416123Phase 13 countries
- Risk-Enabled Therapy After Initiating EV/Pembro for Bladder CancerRecruitingNCT07908979Phase 21 country
- Increasing Pre-Surgical Identification of Muscle Invasive Tumor Evaluations Prior to Planned Cystectomy (INSITE)RecruitingNCT063965331 country
- Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)RecruitingNCT07566156Phase 34 countries
- DBC-664 in Adult Patients With Solid TumorsRecruitingNCT07705035Phase 11 country
- Calcium Electroporation for Urinary Bladder Tumors: A First-in-Human Feasibility, Safety, and Early Response TrialRecruitingNCT07555769Phase 11 country
- A Real-world Study to Learn About of the Characteristics and Outcomes of Advanced or Metastatic Bladder Cancer Patients With Different HistologiesNot yet recruitingNCT07897669
- A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)RecruitingNCT06330064Phase 1/218 countries
- Phase 1 Study of STRO-006 in Adults With Refractory Solid Tumors That Are Recurrent or MetastaticRecruitingNCT07807345Phase 11 country
- A Study of ASP2998 Given by Itself and Given With Standard Therapies in People With Solid TumorsRecruitingNCT07287995Phase 1/22 countries
- Urinary Cell-Free DNA Liquid Biopsy for Urothelial Cancer Diagnosis and Origin IdentificationRecruitingNCT078883741 country
- Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple MyelomaRecruitingNCT06582017Phase 11 country
- GI-101/GI-101A as a Single Agent or in Combination With Pembrolizumab or Lenvatinib in Advanced Solid TumorsRecruitingNCT04977453Phase 1/22 countries
- Sacituzumab Govitecan With or Without Atezolizumab Immunotherapy in Rare Genitourinary Tumors (SMART) Such as High Grade Neuroendocrine Carcinomas, Adenocarcinoma, and Squamous Cell Bladder/Urinary Tract Cancer, Renal Medullary Carcinoma and Penile C...RecruitingNCT06161532Phase 21 country
- Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid TumorsRecruitingNCT06239194Phase 1/21 country
- A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid TumorsRecruitingNCT07749586Phase 1/21 country
- Imaging Study in Metastatic UC, HR+ and HER2- Breast Cancer, TNBC, and NSCLCRecruitingNCT07671092Early Phase 13 countries
- Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid TumorsRecruitingNCT06293898Phase 11 country
- Study of GB-4362 With Enfortumab Vedotin and Pembrolizumab for Advanced Urothelial CancerRecruitingNCT07484022Phase 11 country
- Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial CancerRecruitingNCT07421700Phase 1/26 countries
- A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary TractRecruitingNCT07218380Phase 319 countries
- Prospective Collection And Molecular Analysis Of Biospecimens And Clinical Data From Patients With Urothelial Carcinoma And Related Malignancies Of The Urinary TractRecruitingNCT077891191 country
- Perioperative Systemic Therapies in Muscle-Invasive Bladder Cancer (GUARDIANS)RecruitingNCT078559261 country
- A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid TumorsRecruitingNCT06270706Phase 12 countries
- Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) ProgramRecruitingNCT06265285Phase 21 country
- Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid TumorsRecruitingNCT05176483Phase 113 countries
- Nephroureterectomy With and Without Lymph Node Dissection for Upper Tract Urothelial Cell CarcinomaRecruitingNCT06262516Not applicable1 country
- Trop2-Targeted NIR-II Fluorescent Probe for Identifying Bladder Cancer in Ex Vivo Bladder SamplesRecruitingNCT07848854Phase 21 country
- The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding AreasRecruitingNCT07285044Phase 21 country
- uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With JelmytoRecruitingNCT058749211 country
- A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid TumorsRecruitingNCT07277413Phase 11 country
- Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain MetastasisRecruitingNCT06047379Phase 1/21 country
- N-803 in Combination With Pembrolizumab and Enfortumab Vedotin for Treatment of Urothelial CancerNot yet recruitingNCT07217496Phase 11 country
- A Study of BL-M09D1 in Patients With Locally Advanced or Metastatic Urothelial Carcinoma and Other Solid TumorsNot yet recruitingNCT07837622Phase 21 country
- Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior ImmunotherapyRecruitingNCT06439836Phase 11 country
- Gemcitabine and Carboplatin After Progression on Enfortumab Vedotin and Pembrolizumab in Advanced/Metastatic Urothelial CarcinomaRecruitingNCT07043972Phase 21 country
- Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO TrialNot yet recruitingNCT07576725Phase 21 country
- A Study of BMS-986504 With Standard-of-Care Therapy for People With Solid Tumor CancerRecruitingNCT07532902Phase 11 country
- Named Patient Program for Mitomycin for Pyelocalyceal SolutionAvailableNCT05494411
- Neoadjuvant Enfortumab Vedotin Plus Pembrolizumab in Muscle-Invasive Bladder Cancer and Upper Tract Urothelial CarcinomaNot yet recruitingNCT07643519Phase 2
- A Study of Ivonescimab in Combination With Enfortumab Vedotin vs Pembrolizumab in Combination With Enfortumab Vedotin in Metastatic Urothelial CarcinomaRecruitingNCT07815665Phase 2/31 country
- An Expanded Access Program of Cretostimogene Grenadenorepvec for Treatment of NMIBC for Patients Unresponsive to BCGAvailableNCT064439441 country
- A Home-Based Prehabilitation Exercise Intervention for Improving Physical Function in Patients With Bladder Cancer and Upper Tract Urothelial Cancer, Get Moving TrialRecruitingNCT06040762Not applicable1 country
- Assessment of Decision Tool to Select Women for Gynecologic Sparing Radical CystectomyRecruitingNCT06184516Phase 21 country