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Not yet recruitingNCT07327814MA-StrokeUpdated Jul 16, 2026

Effect of Mental Arithmetic Priming on Gait and Balance in Stroke

An interventional study of Mental Arithmetic and Passive Viewing in Stroke, Hemiparesis and Gait Disorders, sponsored by Lebanese University. Not yet recruiting at 1 site in Lebanon. Open to participants aged 60 Years to 80 Years. Per ClinicalTrials.gov, last updated 2026-07-16.

Sponsored by Lebanese University · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
17
Allocation
Randomized
Ages
60 Years to 80 Years
Sex
All
01

Study summary

This study investigates the effect of cognitive priming through mental arithmetic on functional mobility in post-stroke patients. It hypothesizes that performing mental calculations (addition, subtraction, multiplication) prior to movement stimulates frontoparietal networks, thereby improving gait speed and dynamic balance compared to a passive control condition.

Read the detailed description

Stroke often results in impaired sensorimotor integration and executive dysfunction, leading to gait and balance deficits. Emerging evidence suggests a link between numerical cognition and motor control networks. This randomized controlled trial compares an experimental group (performing 30-second mental arithmetic tasks) against a control group (passive visual exposure). Functional mobility is assessed immediately following the cognitive stimulus using the Ten-Meter Walk Test (10mWT) and the Timed Up and Go (TUG) test to evaluate the immediate "priming" effects of cognitive load on motor performance.

02

Conditions studied

  • Stroke
  • Hemiparesis
  • Gait Disorders
  • Posture
  • Disorders

Keywords

  • Stroke
  • Hemiparesis
  • Posture
  • Balance
  • Gait Disorders
03

In context

Stroke

8,255 studies on the registry are indexed under Stroke; 2,056 are open to participants now.

This study's planned enrollment of 17 is below the median of 49 across 6,024 interventional studies indexed under Stroke.

Browse Stroke studies →

Lead sponsor

Lebanese University is the lead sponsor of 19 studies on the registry; 6 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
60 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Diagnosis of stroke.
  • (MMSE) score ≥ 23.
  • Ability to walk 10 meters independently (with or without assistive device).

Exclusion criteria

Exclusion Criteria:

  • Hemianopia.
  • Wernicke's aphasia or Global aphasia.
  • Orthopedic injuries or recent surgeries affecting the lower limbs.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

MMSE and MoCA

Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
17 participants (estimated)

Study arms

  • Experimental
    Intervention: Behavioral: Mental Arithmetic

    Visual presentation of arithmetic equations (Addition, Subtraction, Multiplication) projected on a screen. Participants must calculate and verbally report the answer within a 10-second window per equation.

    Behavioral: Mental Arithmetic

  • Placebo comparator
    Passive Viewing

    Passive viewing of a black screen with no cognitive demand.

    Behavioral: Passive Viewing

Interventions

  • BehavioralMental Arithmetic

    Visual presentation of arithmetic equations (Addition, Subtraction, Multiplication) projected on a screen. Participants must calculate and verbally report the answer within a 10-second window per equation.

  • BehavioralPassive Viewing

    Passive viewing of a black screen with no cognitive demand.

06

What researchers measure

Primary outcomes

  1. Gait Speed (10mWT)

    Assessed using the Ten-Meter Walk Test (10mWT). Participants walk 14 meters; time is recorded for the middle 10 meters to determine steady-state gait speed.

    Time frame: Immediately following the 30-second cognitive stimulus.

  2. Dynamic Balance (TUG)

    Assessed using the Timed Up and Go (TUG) test. Time taken to stand from a chair, walk 3 meters, turn, walk back, and sit down.

    Time frame: Immediately following the 30-second cognitive stimulus.

07

Study locations

1 site
  • Faculty of Public Health, Branch 1
    Beirut, Lebanon
08

References and documents

Publications

  • Khayat J, Champely S, Diab A, Rifai Sarraj A, Fargier P. Effect of mental calculus on the performance of complex movements. Hum Mov Sci. 2019 Aug;66:347-354. doi: 10.1016/j.humov.2019.05.008. Epub 2019 May 28. No abstract available. PubMed 31146193 ↗

Individual participant data

Plan to share: Yes — Individual participant data (IPD) that underlie the results reported in this article (after de-identification) will be shared. This includes the data used to generate the tables and figures.

Supporting information: Study protocol, Statistical analysis plan, Informed consent form

Time frame: Data will be available beginning 6 months and ending 5 years following article publication.

Access criteria: Data will be shared with researchers who provide a methodologically sound proposal to the corresponding author. Proposals should be directed to ahmadrifaisarraj@ul.edu.lb. To gain access, data requestors will need to sign a data access agreement.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Start is estimated for Sep 2026; primary completion for Dec 2026, 3 months later.

Of 3,108 non-industry interventional studies with no phase under Stroke, half reached primary completion within 23 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 46. This study's planned 3 months is below that.

Counting every sponsor, half of 3,252 studies reached it within 23 months; a quarter within 10 and three quarters within 46.

How these figures are worked out, and which studies are left out of them.

Registered
Dec 25, 2025
First posted
Jan 8, 2026
StartEst.
Sep 1, 2026
Primary completionEst.
Dec 25, 2026
CompletionEst.
Jan 1, 2027
Last update
Jul 16, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jul 16, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07327814
Lead sponsor
Lebanese University
Responsible party
Ahmad Rifai Sarraj (Professor, Lebanese University) — Principal investigator
First posted
Jan 8, 2026
Start date
Sep 1, 2026 (estimated)
Primary completion
Dec 25, 2026 (estimated)
Completion
Jan 1, 2027 (estimated)
Last update
Jul 16, 2026

Study contacts

Ahmad I. Rifai Sarraj, PhD
Contact
ahmadrifaisarraj@ul.edu.lb
+9613662956
Jihan Allaw, Master
Contact
jihan.allaw.1@ul.edu.lb

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.

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