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CompletedNCT07294456Updated Dec 29, 2025

Periodontal Status and Disease Severity in Hidradenitis Suppurativa Patients

An observational study in HİDRADENİTİS SUPPURATİVA, sponsored by Saglik Bilimleri Universitesi. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Minutes and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-12-29.

Sponsored by Saglik Bilimleri Universitesi · Observational

Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
226
Ages
18 Minutes and older
Sex
All
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Study summary

This cross-sectional study aims to evaluate the periodontal status of individuals diagnosed with hidradenitis suppurativa (HS) and to compare them with systemically healthy controls. HS is a chronic inflammatory skin disease characterized by recurrent lesions and systemic inflammation, which may influence periodontal health. In this study, periodontal parameters-including probing depth, clinical attachment loss, gingival index, plaque index, and bleeding on probing-will be assessed using standard clinical methods. Dermatological examination will include disease duration, lesion characteristics, and Hurley staging. The study will investigate the prevalence of periodontitis in HS patients and explore potential associations between periodontal findings and HS severity. Findings from this research may provide insight into shared inflammatory pathways and contribute to understanding the possible link between HS and periodontal disease.

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Conditions studied

  • HİDRADENİTİS SUPPURATİVA

Keywords

  • HİDRADENİTİS SUPPURATİVA
  • PERİODONTAL DİSEASE
  • PERİODONTİTİS
  • GİNGİVAL İNFLAMMATİON
03

In context

Hidradenitis Suppurativa

284 studies on the registry are indexed under Hidradenitis Suppurativa; 87 are open to participants now.

This study's enrollment of 226 is above the median of 170 across 72 observational studies indexed under Hidradenitis Suppurativa.

Browse Hidradenitis Suppurativa studies →

Lead sponsor

Saglik Bilimleri Universitesi is the lead sponsor of 453 studies on the registry; 140 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Minutes and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

The study population consists of adult individuals with a confirmed diagnosis of hidradenitis suppurativa and age-matched healthy controls, each having at least 12 teeth (excluding third molars), and no recent periodontal or systemic treatment.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Having a diagnosis of hidradenitis suppurativa.
  • Age greater than 18 years.
  • Presence of at least 12 teeth in the mouth, excluding third molars.

Exclusion criteria

Exclusion Criteria:

  • Age under 18 years.
  • Pregnancy.
  • Breastfeeding.
  • Receiving treatment for periodontitis or hidradenitis suppurativa within the past 3 months.
  • Use of antibiotics, anti-inflammatory drugs, or immunomodulatory medications within the past 3 months.
05

Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
226 participants (actual)
Patient registry
No

Groups and cohorts

  • Hidradenitis Suppurativa Group

    Participants diagnosed with hidradenitis suppurativa undergoing periodontal examination.

    Other: No intervention (observational study)

  • Healthy Control Group

    Systemically healthy individuals without hidradenitis suppurativa undergoing periodontal examination.

    Other: No intervention (observational study)

Interventions

  • OtherNo intervention (observational study)

    Observational study with no treatment or intervention applied.

06

What researchers measure

Primary outcomes

  1. Correlation Between Periodontal Status and Hidradenitis suppurativa

    Time frame: Baseline (single assessment)

Secondary outcomes

  1. Correlation between Periodontal Status and Hurley Stage

    Time frame: Baeline (single assesment)

  2. Corralation between Hurley Stage and Oral Health Impact Profile OHIP-14) Score

    Time frame: baseline (single assesment)

  3. Correlation between Dermatology Life Quality Index (DLQI) and Oral Health Impact Profile (OHIP-14) Total Score

    Time frame: baseline (single assesment)

07

Study locations

1 site
  • University of Health Sciences, Gülhane Faculty of Dentistry
    Ankara, None Selected 6220, Turkey (Türkiye)
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References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 29, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07294456
Responsible party
Şeyma Çardakçı (ASSİSTANT PROFESSOR, Saglik Bilimleri Universitesi) — Principal investigator
First posted
Dec 19, 2025
Start date
Jun 1, 2025
Primary completion
Sep 1, 2025
Completion
Sep 15, 2025
Last update
Dec 29, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2025. You cannot join it, but the record below documents what was studied.

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