An observational study in Patient Survival, Graft Survival and Liver Disease (Alcoholic or Not), sponsored by University of Jena. Completed at 1 site in Canada. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-02-13.
Sponsored by University of Jena · Observational
This observational study aims to investigate the impact of gender disparity between donors and recipients on long-term outcomes after liver transplantation (LT). The study aims to answer the following question:
Does gender mismatch lower the possibility of survival after liver transplantation? Participants demonstrate gender dicrepancies between donors and recipients as regular concept in LT. The retrospective cohort study investigates the impact over a long-term follow up of 10 years.
The study involves patients who undergo liver transplantation at the Ajmera Transplant Centre Toronto from 2014 until 2022. The observation period ended at the first January 2025 to provide a minimal follow up of 24 months.
Liver transplant recipients with gender mismatch (A) will be compared with liver transplant recipients without gender mismatch (B).
Liver transplantation is the only curative treatment for people with end stage liver disease. Gender mismatch between donor and recipient, particularly, the combination of a female donor to male recipient has been controversial in the past. Identifying risk factors that could affect the survival of the graft and recipient is of the utmost importance.
824 studies on the registry are indexed under Liver Diseases; 152 are open to participants now.
This study's enrollment of 1,146 is above the median of 200 across 262 observational studies indexed under Liver Diseases.
Browse Liver Diseases studies →University of Jena is the lead sponsor of 89 studies on the registry; 3 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients who underwent liver transplantation at who at the Ajmera transplant centre, Toronto between 2014 and 2022
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Liver transplant recipients with gender mismatch
Liver transplant recipients without gender mismatch
Patient survival
Overall survival of patients who underwent liver transplantation at the Ajmera transplant centre toronto between 2014 and 2022
Time frame: Liver transplantation between 01.01.2014 and 01.01.2022, Patient Survival: observatory period between 01.01.2014 and 01.01.2024
Plan to share: Undecided — The investigators consider not to share IPD before publishing the study.
This study is completed, as verified in Oct 2025. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
University of Jena