ClinicalTrials.gg
RecruitingNCT07247669TrIAje ProjectUpdated May 13, 2026

Evaluation and Optimization of Telephone Triage Using Artificial Intelligence (AI) Models for the Detection of Demands for Time-dependent Pathology at the Emergency and Urgent Care Coordination Center (CCUE).

An observational study in Chest Pain, Stroke Acute and Respiratory Failure, sponsored by Centro de Emergencias Sanitarias 061 Andalucía. Recruiting at 1 site in Spain. Per ClinicalTrials.gov, last updated 2026-05-13.

Sponsored by Centro de Emergencias Sanitarias 061 Andalucía · Observational

From the registry’s dates

  • Primary completion was expected by Jun 2026, 5 months ago, but the record still lists the study as recruiting.
  • Started Mar 2025; still recruiting 1 year 8 months later.
Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
5,000,000
Sex
All
01

Study summary

Improving Telephone Triage in Emergency Calls with AI The Coordinating Centre for Urgencies and Emergencies in Andalusia (CCUE) handles thousands of calls every day. Each call needs to be assessed based on the information given over the phone to determine how serious the case is. The reasons for calling range from minor health issues to life-threatening emergencies like cardiac arrest (CPA).

This project focuses on improving telephone triage for four key emergency situations that often indicate severe or life-threatening conditions:

Unconsciousness / Cardiac arrest Difficulty breathing Chest pain (non-traumatic, possible heart-related issues) Stroke symptoms Our goal is to make telephone triage more accurate and efficient by using advanced Artificial Intelligence (AI) techniques, including Machine Learning (ML) and Natural Language Processing (NLP). These tools will help CCUE operators make better and faster decisions, ensuring that patients receive the right care as quickly as possible.

How it will be done:

The investigators will analyze anonymized historical call data from the emergency coordination system (CCR) and digital clinical records (HCDM). This includes:

Structured data: Predefined fields, such as answers to standard triage questions.

Unstructured data: Free-text notes and other information recorded during the call.

A hybrid AI approach will be used, combining:

Traditional AI methods (supervised learning and deep learning) to classify cases.

Generative AI techniques (advanced language models) to extract useful insights from free-text data.

Building the Best Prediction Model

To find the most effective AI model, we will test different machine learning techniques, including:

Decision Trees Random Forests Support Vector Machines (SVM) XGBoost Ensemble methods Neural Networks We will also analyze which questions and variables are the most important in predicting the severity of a case. Based on this, we will suggest improvements to the current triage questions to enhance accuracy.

Measuring Success

We will evaluate the AI model using key performance metrics, including:

Accuracy (overall correctness) Sensitivity (ability to detect real emergencies) Specificity (ability to avoid false alarms) False Positive \& False Negative Rates (how often the system makes mistakes) Likelihood Ratios (how well the system distinguishes between urgent and non-urgent cases) F1-Score \& ROC Curve (overall performance indicators) Why This Matters This project will assess how effective the current telephone triage system is and develop a new AI-powered model to improve it. The goal is to help emergency operators quickly identify the most serious cases, reducing response times and improving patient outcomes. In the future, the investigators aim to integrate this improved AI model into the CCUE system to enhance emergency response across Andalusia.

Read the detailed description

The Emergency and Urgent Care Coordination Center in Andalusia (CCUE) receives thousands of calls daily, during which each case must be classified by severity level based on the information provided over the phone. The conditions for which citizens seek help span a wide range-from minor ailments to cardiac arrest. This project addresses the challenge of telephone triage in out-of-hospital emergencies for several frequent reasons for care requests that may indicate emergent and potentially life-threatening medical conditions: unconsciousness/cardiac arrest, respiratory distress, non-traumatic chest pain, and stroke.

The goal is to improve the accuracy and efficiency of telephone triage using advanced Artificial Intelligence (AI) techniques-both symbolic and generative-including machine learning (ML) and natural language processing (NLP). This will enable CCUE CES-061 Andalucía operators to make faster, more informed decisions to provide timely and appropriate care.

The investigators will collect anonymized historical data from calls related to these four care request categories, extracted from the relational database systems of the Networked Coordination Centers (CCR) and the Mobile Digital Health Record (HCDM) of CES-061 Andalucía. The analysis will include both structured data (predefined fields with specific formats, including triage questions asked during the call) and unstructured data (free text and other formats) generated during demand management, encompassing coordination and care delivery aspects.

The investigators will implement a hybrid approach that integrates classical AI techniques (supervised and deep learning for classification) with generative AI (large language models to analyze and extract valuable insights from unstructured data). Various classification algorithms-such as decision trees, random forests, SVM, XGBoost, ensemble methods, and neural networks-will be tested to build the most accurate predictive model.

Through feature importance analysis, we will identify the most predictive questions and variables, proposing modifications to the current triage questions to enhance prediction accuracy.

The model will be evaluated using multiple metrics (including accuracy, sensitivity, specificity, positive and negative likelihood ratios, false positive rate [alarm failure], false negative rate [omission failure], area under the ROC curve, and F1-score). These metrics will help assess the model's ability to correctly predict final diagnoses-maximizing detection of truly urgent cases (high sensitivity, high positive likelihood ratio, and low false negative rate) while avoiding excessive false positives (high specificity, low false positive rate, and low negative likelihood ratio).

The aim of this project is to assess the effectiveness of the current CCUE telephone triage model and develop a new AI-based model to improve it. We aim to provide a solid foundation for future implementation of the improved model within CCUEs, helping personnel to quickly identify and prioritize the most severe cases, ultimately reducing response times and improving health outcomes.

02

Conditions studied

  • Chest Pain
  • Stroke Acute
  • Respiratory Failure
  • Cardiac Arrest (CA)
  • Coma

Keywords

  • Emergency Medical Communication Center
  • Triage Telephone
  • Emergency Medical Services
  • Priority
  • Machine Learning
  • Artificial Intelligence
03

In context

Chest Pain

388 studies on the registry are indexed under Chest Pain; 64 are open to participants now.

This study's planned enrollment of 5,000,000 is above the median of 489 across 167 observational studies indexed under Chest Pain.

Browse Chest Pain studies →

Lead sponsor

Centro de Emergencias Sanitarias 061 Andalucía is the lead sponsor of 3 studies on the registry; 2 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

All patients who have requested telephone assistance in the last five years to the Medical Dispatch Center in Andalusia.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

Telephone calls recorded with codes A36 + A58 (unconsciousness/cardiorespiratory arrest), A16 (respiratory distress), A23 (non-traumatic chest pain) and A54 (stroke).

Exclusion criteria

Exclusion Criteria:

  • Demands with relevant information about the patient or the event incomplete or absent.
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
5,000,000 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Detection of critical severity from Medical Dispatch Center

    the medical dispatch center has to Detect a Time dependent pathology (the ones that are life-threatening emergencies).Minutes from call receipt to recognition of a life-threatening emergency (time dependent pathology)

    Time frame: 24 hours. From the call receipt to medical team dispatch

Secondary outcomes

  1. Effectiveness

    Effectiveness of the current telephone triage system for these demands in the CCUE of Andalusia, using clinically relevant performance metrics, especially under-triage and over-triage (including accuracy, sensitivity, specificity, positive and negative likelihood ratios, false positive and false negative rates, area under the ROC curve and F1-score).

    Time frame: one year

  2. Artificial Intelligence Model Design

    Engineers have to develop and validate an Artificial Intelligence (AI) model that integrates classical AI and generative AI techniques to improve the accuracy and efficiency of telephone triage of users requesting assistance for unconsciousness/cardiorespiratory arrest (registered in the system as types of demands A36 and A58 respectively), respiratory distress (A16), non-traumatic chest pain (A23) and stroke (A54) in the Emergency and Urgency Coordination Centres (CCUE) of Andalusia.

    Time frame: 2 years

  3. Performance of Artificial Intelligence (AI) models in dispatch medical center

    Engineers have to performance different AI algorithms in predicting the severity of telephone calls for unconsciousness/cardiopulmonary arrest, respiratory distress, non-traumatic chest pain, and stroke, using structured and unstructured data from the CCR and HCDM databases.

    Time frame: 2 years

07

Study locations

1 of 1 sites recruiting
  • Centro de Emergencias Sanitarias 061
    Málaga, Málaga 29590, Spain
    Recruiting
    • María José MJ Luque-Hernández, MD PhD · Contactmariajose.luque.sspa@juntadeandalucia.es · +34 617563352
    • María José Luque Hernández, Doctor of Medicine, PhD · Principal investigator
    • CRISTINA LÓPEZ LÓPEZ, Doctor of Medicine · Sub investigator
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 13, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07247669
Lead sponsor
Centro de Emergencias Sanitarias 061 Andalucía
Collaborators
Junta de Andalucia, Andaluz Health Service
Responsible party
Sponsor
First posted
Nov 25, 2025
Start date
Mar 1, 2025
Primary completion
Jun 1, 2026 (estimated)
Completion
Dec 31, 2027 (estimated)
Last update
May 13, 2026

Study contacts

María José MJ Dr. Luque Hernández, MD PhD
Contact
mariajose.luque.sspa@juntadeandalucia.es
0034 617563352

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Interested in this study?

Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.

Contact study team

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion