An observational study in Kidney Disease, Kidney Disease, Chronic and Kidney Disease, End-Stage, sponsored by Rutgers, The State University of New Jersey. Recruiting at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-04-24.
Sponsored by Rutgers, The State University of New Jersey · Observational
The goal of this observational study is to learn more about how genes impact the risk of kidney disease. Anyone 18 or older living in the US is eligible, and a diagnosis of kidney disease is NOT required. Study participation is online, and it takes about 20 minutes to complete health surveys and request a saliva collection kit sent through US mail. In return, study participants may opt to receive information about their genetic ancestry at no cost.
This is an online research study to learn more about how genes affect the risk of kidney disease. This is an online research study to learn more about how genes affect the risk of kidney disease. No office visit is required and in return, participants may receive information about their genetic ancestry for free. One in seven individuals in the United States today has chronic kidney disease (CDC 2023). The heritability -a measure of genetic, as opposed to environmental, contribution to a disease- of kidney function such as the estimated glomerular filtration rate (eGFR) has been estimated at 38%This study will increase our understanding of the genetic basis of kidney disease, which is a crucial step in drug development to improve current treatment options. The study investigators seek a diverse population because diversity among participants maximizes the usefulness of the data. Participants will use our online study portal to answer questions about their health and provide their DNA via a saliva sample using a pre-paid mailer. Participation takes approximately 20 minutes. Participants will be invited to share data from their electronic health records, but this is not required for study participation. The study investigators keep participants engaged with short monthly newsletters.
3,840 studies on the registry are indexed under Kidney Diseases; 500 are open to participants now.
This study's planned enrollment of 50,000 is above the median of 192 across 1,033 observational studies indexed under Kidney Diseases.
Browse Kidney Diseases studies →Rutgers, The State University of New Jersey is the lead sponsor of 496 studies on the registry; 130 are open to participants now.
Of its 38 completed or terminated interventional studies of FDA-regulated products, 30 (79%) have results posted.
Counted across the registry records on this site, refreshed daily.
The study population consists of anyone at least 18 years old who lives in the United States, including both individuals who have or had kidney disease and those who have not. Participants include males, females, non-binary, and all race-ethnic groups.
Exclusion Criteria:
Study participants who have been diagnosed with any form of kidney disease, either currently or in the past.
Genetic: Saliva sample · Other: Health surveys
Study participants who have never been diagnosed with any form of kidney disease, either currently or in the past.
Genetic: Saliva sample · Other: Health surveys
Saliva sample is sent via prepaid US Mail for DNA extraction
Health surveys are filled out online in the study portal.
Genetic risk variants associated with kidney disease
Genetic factors will be measured through whole exome sequencing along with genotyping of common variants, and then correlated with kidney disease and/or kidney disease subtype.
Time frame: 2 years
Plan to share: No
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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Rutgers, The State University of New Jersey