An interventional study of 12 week training and 12 week training in Inflammation, Oxidative Stress and Plasma Volume, sponsored by Habil Hamdouni. Completed at 1 site in Tunisia. Per ClinicalTrials.gov, last updated 2025-09-24.
Sponsored by Habil Hamdouni · Not applicable, Interventional, and Treatment
Considering the remarkable increase of the fitness programs, the purpose of this study was to assess and compare the effect of Crossfit (CF) and periodized resistance (RT) trainings on inflammatory/oxidative responses in untrained individuals.
Twenty-four participants (20 men and 4 women, age= 25.7 ± 2.2 years, BMI= 25.7 kg.m-2) were randomly assigned into 12 weeks of these trainings with a rate of five sessions/week. Before and after intervention, participants anthropometric data and graded exercise tests were performed. Before (pre), immediately after (post) and 60min after test (p60) a 20mL venous blood sample were drawn for a later measure of c-reactive protein (CRP), interleukin 1 beta (IL-1ß), tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-6), interleukin 10 (IL-10), thiobarbituric acid reactive substances (TBARS), antioxidant enzymes catalase (CAT) and glutathione peroxidase (GPx).
3,439 studies on the registry are indexed under Inflammation; 629 are open to participants now.
This study's enrollment of 24 is below the median of 50 across 2,437 interventional studies indexed under Inflammation.
Browse Inflammation studies →Habil Hamdouni is the lead sponsor of 2 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
High intensity functional training
Behavioral: 12 week training
Periodized resistance training
Behavioral: 12 week training
Anti-inflammatory and oxidative environment following 12-weeks of CF training by evaluating inflammatory markers and oxidative precursors in untrained participants
Anti-inflammatory and oxidative environment following 12-weeks of resistance training by evaluating inflammatory markers and oxidative precursors in untrained participants
Inflammatory marker
c-reactive protein (CRP),
Time frame: Participants data were performed in one day before beginning the 12 week intervention and one day after the last session
Inflammatory marker
interleukin 1 beta (IL-1ß)
Time frame: Participants data were performed in one day before beginning the 12 week intervention and one day after the last session
Inflammatory marker
tumor necrosis factor alpha (TNF-α)
Time frame: Participants data were performed in one day before beginning the 12 week intervention and one day after the last session
Inflammatory marker
interleukin 6 (IL-6)
Time frame: Participants data were performed in one day before beginning the 12 week intervention and one day after the last session
Inflammatory marker
interleukin 10 (IL-10)
Time frame: Participants data were performed in one day before beginning the 12 week intervention and one day after the last session
Oxidative stress
thiobarbituric acid reactive substances (TBARS)
Time frame: Participants data were performed in one day before beginning the 12 week intervention and one day after the last session
Oxidative stress
antioxidant enzymes catalase (CAT)
Time frame: Participants data were performed in one day before beginning the 12 week intervention and one day after the last session
Oxidative stress
glutathione peroxidase (GPx)
Time frame: Participants data were performed in one day before beginning the 12 week intervention and one day after the last session
Plan to share: Undecided — Under negotation
No publications or documents are linked to this record.
This study is completed, as verified in Sep 2025. You cannot join it, but the record below documents what was studied.
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Habil Hamdouni