A Phase 1 interventional study of LY3537031 in Renal Impairment, Healthy and Renal Insufficiency, sponsored by Eli Lilly and Company. Completed at 4 sites in 2 countries. Open to participants aged 18 Years to 85 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-04-24.
Sponsored by Eli Lilly and Company · Phase 1, Interventional, and Basic science
The purpose of this study is to assess the amount of LY3537031 that reaches the bloodstream and the time it takes for the body to get rid of it when given to participants with renal (kidney) impairment and to healthy participants.
1,994 studies on the registry are indexed under Renal Insufficiency; 173 are open to participants now.
This study's enrollment of 31 is below the median of 43 across 1,503 interventional studies indexed under Renal Insufficiency.
Browse Renal Insufficiency studies →Eli Lilly and Company is the lead sponsor of 2,048 studies on the registry; 140 are open to participants now.
Of its 521 completed or terminated interventional studies of FDA-regulated products, 341 (65%) have results posted.
Counted across the registry records on this site, refreshed daily.
Additional Inclusion Criteria for Healthy Participants in Control Group:
Additional Inclusion Criteria for Participants with Severe Renal Impairment or with End-Stage Renal Disease (ESRD):
Exclusion Criteria:
LY3537031 administered subcutaneously (SC) in a control group of participants with normal renal function
Drug: LY3537031
LY3537031 administered SC in groups of participants with impaired renal function
Drug: LY3537031
LY3537031 administered SC in a group of participants with end-stage renal disease (ESRD) on hemodialysis
Drug: LY3537031
Administered SC
Pharmacokinetics (PK): Area Under the Concentration Versus Time Curve (AUC) of LY3537031
PK: AUC of LY3537031
Time frame: Predose on day 1 up to week 8 post dose
PK: Maximum Concentration (Cmax) of LY3537031
PK: Cmax of LY3537031
Time frame: Predose on day 1 up to week 8 post dose
Plan to share: No
This study is completed, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.
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