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Active, not recruitingNCT07156357sEMGUpdated Jul 17, 2026

Surface EMG Testing on Swallowing in EoE Patients

An observational study in Eosinophilic Esophagitis (EoE), sponsored by Mayo Clinic. Active, not recruiting at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-17.

Sponsored by Mayo Clinic · Observational

Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
30
Ages
18 Years and older
Sex
All
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Study summary

Evaluating swallowing food with surface electromyography (EMG) machine in patients with Eosinophilic Esophagitis

Read the detailed description

Evaluating surface electromyography (sEMG) assessment of swallowing and bolus preparation in patients with Eosinophilic Esophagitis (EoE).

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Conditions studied

  • Eosinophilic Esophagitis (EoE)
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In context

Eosinophilic Esophagitis

235 studies on the registry are indexed under Eosinophilic Esophagitis; 53 are open to participants now.

This study's planned enrollment of 30 is below the median of 84 across 86 observational studies indexed under Eosinophilic Esophagitis.

Browse Eosinophilic Esophagitis studies →

Lead sponsor

Mayo Clinic is the lead sponsor of 3,218 studies on the registry; 670 are open to participants now.

Of its 445 completed or terminated interventional studies of FDA-regulated products, 313 (70%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Patients with EoE will be recruited from the esophageal clinic. Controls will be recruited by monitoring for patients that present for video swallow with speech language pathology and have a normal video swallow.

Inclusion criteria

  • Controls

    • Normal video swallow or score of 0 for dysphagia on ESSAI questionnaire
    • absence of dysphagia
    • age >18 EoE participants
    • Documentation of EoE diagnosis by histologic criteria,
    • >15 eos/hpf on most recent esophageal biopsy
    • age >18

Exclusion criteria

Exclusion Criteria:

  • Abnormal baseline video swallow
  • lack of MSK coordination to eat test meal
  • underlying neuromuscular disorder.
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Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
30 participants (estimated)
Patient registry
No

Groups and cohorts

  • Controls

    Subjects who can swallow normally

    Diagnostic Test: Surface Electromyography · Diagnostic Test: Fiberoptic Endoscopic Evaluation of Swallowing

  • Eosinophilic Esophagitis

    Subjects with Eosinophilic Esophagitis

    Diagnostic Test: Surface Electromyography · Diagnostic Test: Fiberoptic Endoscopic Evaluation of Swallowing

Interventions

  • Diagnostic testSurface Electromyography

    Tests performed to evaluate swallowing function

  • Diagnostic testFiberoptic Endoscopic Evaluation of Swallowing

    Assessment of swallowing function

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What researchers measure

Primary outcomes

  1. Preparatory phase time

    Comparison of preparatory phase between cohorts

    Time frame: Through study completion an average of 2 days

Secondary outcomes

  1. Time difference in swallow initiation

    Time difference in swallow initiation between fiberoptic endoscopic evaluation of swallowing (FEES) vs sEMG

    Time frame: Through study completion an average of 2 days

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Study locations

1 site
  • Mayo Clinic
    Rochester, Minnesota 55905, United States
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 17, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07156357
Lead sponsor
Mayo Clinic
Responsible party
Karthik Ravi, M.D. (Principal Investigator, Mayo Clinic) — Principal investigator
First posted
Sep 5, 2025
Start date
Aug 4, 2025
Primary completion
Oct 2026 (estimated)
Completion
Jun 2027 (estimated)
Last update
Jul 17, 2026

Study contacts

Karthik Ravi, MD
principal investigator · Mayo Clinic

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.

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