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Not yet recruitingNCT07143851Updated Aug 27, 2025

Multi-modal Intelligent Diagnosis System for Multiple Ophthalmic Diseases

An observational study in Retina Disease and Glaucoma, sponsored by Beijing Hospital. Not yet recruiting. Open to participants aged 20 Years to 90 Years. Per ClinicalTrials.gov, last updated 2025-08-27.

Sponsored by Beijing Hospital · Observational

Study type
Observational
Model
Other
Time perspective
Cross-sectional
Enrollment
5,000
Ages
20 Years to 90 Years
Sex
All
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Study summary

Aiming at the problems of low image reading efficiency, crowded medical resources and fragmented cross-modal information of ophthalmic OCT and OCTA, a multimodal large model diagnostic framework for various diseases such as retinal diseases and optic nerve damage in glaucoma is constructed to fully explore the complementary information of various images such as SS-OCT structural images, SS-OCTA vascular images and optic nerve scans. Extract cross-modal joint features to improve the accuracy of automatic diagnosis.

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Conditions studied

  • Retina Disease
  • Glaucoma

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03

In context

Glaucoma

1,818 studies on the registry are indexed under Glaucoma; 231 are open to participants now.

This study's planned enrollment of 5,000 is above the median of 103 across 454 observational studies indexed under Glaucoma.

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Lead sponsor

Beijing Hospital is the lead sponsor of 51 studies on the registry; 22 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
20 Years to 90 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Patients diagnosed as macular degeneration, diabetic macular edema, retinal vein obstructive macular edema, high myopia, glaucoma or other clearly diagnosed ophthalmic diseases.

Inclusion criteria

  • Diagnosed as macular degeneration, diabetic macular edema, retinal vein obstructive macular edema, high myopia, glaucoma or other clearly diagnosed ophthalmic diseases. The SS-OCT/SS-OCTA images of the patient are clear.

Exclusion criteria

Exclusion Criteria:

  • The image quality is poor and difficult to analyze due to reasons such as refractive media opacity and poor coordination.
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Study design

Observational model
Other
Time perspective
Cross-sectional
Enrollment
5,000 participants (estimated)
Target follow-up
1 Day
Patient registry
Yes

Interventions

  • OtherNot applicable- observational study

    There is no special intervention method

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What researchers measure

Primary outcomes

  1. CMT

    Central macular thickness measured on OCT

    Time frame: Baseline

Secondary outcomes

  1. SS-OCT/OCTA images

    Multimodal features based on patients' iamges

    Time frame: Baseline

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Study locations

No study locations are listed for this record.

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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 27, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07143851
Lead sponsor
Beijing Hospital
Responsible party
Sponsor
First posted
Aug 27, 2025
Start date
Aug 30, 2025 (estimated)
Primary completion
Jun 30, 2028 (estimated)
Completion
Jun 30, 2028 (estimated)
Last update
Aug 27, 2025
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Aug 2025. You cannot join it, but the record below documents what was studied.

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Discussion

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