An observational study in AMD - Age-Related Macular Degeneration, sponsored by University of Trieste. Not yet recruiting at 1 site in France. Per ClinicalTrials.gov, last updated 2025-08-27.
Sponsored by University of Trieste · Observational
The goal of this observational study is to compare swept source optical coherence tomography devices ability to detect macular neovascularisation when there is a large pigment epithelium detachment higher than 250 microns
1,459 studies on the registry are indexed under Macular Degeneration; 238 are open to participants now.
This study's planned enrollment of 50 is below the median of 110 across 409 observational studies indexed under Macular Degeneration.
Browse Macular Degeneration studies →University of Trieste is the lead sponsor of 39 studies on the registry; 8 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients treated for neovascular age related macular degeneration (AMD)
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Two Optical Coherence Tomography Angiography swept source devices are compared for the detection of large pigment epithelium detachments in age related macular degeneration. The sensitivity of the devices is compared in both the automatic segmentation done by the device and the manual segmentation done by a retina specialist.
Sensitivity of the detection of neovascularisation in large pigment epithelium detachment by swept source optical coherence tomography devices
The optical coherence tomography angiography devices are known to have a difficult time detecting neovascularisation in the cases of large pigment epithelium detachments (PED), because of the many layers and the distance the OCT signal has to cross. The automatic retina segmentation (done by the device of the different retina layers plays a big role in this detection. It's also disturbed by the height of the PED. This study aims to compare the sensitivity of two swept source OCT devices available in the market : Bmizar, Towardpi and Plexelite, Zeiss. After the exam image acquisition, a retina specialist will try to make a manual segmentation of the retina analysed to help the detection of macular neovascularisation that would have been missed in the "normal" automatic segmentation done by the device.
Time frame: Day 1
Plan to share: No
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Start is estimated for Aug 2025; primary completion for Sep 2025, 1 month later.
Of 104 non-industry observational studies under Macular Degeneration, half reached primary completion within 48 months of starting (the median), counting those still running; a quarter within 20 and three quarters within 98. This study's planned 1 month is below that.
Counting every sponsor, half of 160 studies reached it within 45 months; a quarter within 16 and three quarters within 77.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.
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University of Trieste