An interventional study of miniscrew- supported maxillary posterior segments' intrusion using clear aligners in Skeletal Open Bite, Open Bite and Maxillary Intrusion, sponsored by Cairo University. Active, not recruiting at 1 site in Egypt. Per ClinicalTrials.gov, last updated 2025-08-12.
Sponsored by Cairo University · Not applicable, Interventional, and Treatment
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Brief Summary: Comparative Management of Skeletal Anterior Open Bite Using Mini-Screw Supported Intrusion with Clear Aligners Versus Fixed Appliances
PICO elements
Population: Adults (17-25 years) with uncompensated skeletal anterior open bite.
Intervention: TAD-supported intrusion with clear aligners. Comparison: TAD-supported intrusion with fixed appliances.
Outcomes:
Primary: Anterior open bite closure. Secondary: Molar intrusion, mandibular autorotation, incisor movement and quality of life.
The aim of the study is to compare the effects of mini-screw supported maxillary posterior segments' intrusion using fixed appliances versus clear aligners.
34 studies on the registry are indexed under Open Bite; 8 are open to participants now.
This study's planned enrollment of 8 is below the median of 30 across 28 interventional studies indexed under Open Bite.
Browse Open Bite studies →Cairo University is the lead sponsor of 4,941 studies on the registry; 1,458 are open to participants now.
Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
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Exclusion Criteria:
miniscrew-supported maxillary posterior segments' intrusion will be done using fixed appliances
Device: miniscrew- supported maxillary posterior segments' intrusion using clear aligners
maxillary posterior segments will be intruded with the aid of miniscrews and clear aligners
Anterior open bite closure
the anterior open bite will be measured between the incisors using a digital caliper
Time frame: 6 months
amount of maxillary posterior teeth intrusion
the distance between the molar tri-furcation/premolar center to the Frankfurt Horizontal plane
Time frame: 6 months
Amount of mandibular posterior teeth extrusion
the distance between molar bi-furcation or premolar center to the mandibular plane
Time frame: 6 months
Plan to share: No
No publications or documents are linked to this record.
Started Dec 2024 (actual). Primary completion is estimated for Dec 2025, 12 months after the start.
Of 24 interventional studies with no phase under Open Bite, half reached primary completion within 17 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 36. This study's planned 12 months is below that.
How these figures are worked out, and which studies are left out of them.
This study is active, not recruiting, as verified in Aug 2025. You cannot join it, but the record below documents what was studied.
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