ClinicalTrials.gg
CompletedNCT07104994Updated Aug 5, 2025

Inferior Alveolar Nerve Translocation With Dental Implant Placement in Severely Resorbed Mandibles

An interventional study of Dental implant in Sever Mandibular Bone Resorption, Sensory Defect and Implant Failure, sponsored by University of Science and Technology, Yemen. Completed at 1 site in Yemen. Per ClinicalTrials.gov, last updated 2025-08-05.

Sponsored by University of Science and Technology, Yemen · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 1 year 1 month after the study started (first participant enrolled Jun 2024, registered Jul 2025).
Phase
Not applicable
Study type
Interventional
Enrollment
9
Allocation
Not applicable
Sex
All
01

Study summary

This study investigates the effects of inferior alveolar nerve lateralization on the post-implant insertion sensory outcome for patients with severe mandibular bone resorption.

Read the detailed description

This is a prospective randomized clinical trial. The study was carried out in patients with posterior mandibular atrophies among selected cases from patients attending the Faculty of Dentistry dental polyclinics, and some private dental clinics in Sana'a city The age of patients was above the age of 18 years All patients received a thorough dental examination (extra-oral and intra-oral examination) in dental clinics using a dental mirror, ball-tipped World Health Organization (WHO) dental prob, and dental tweezers. Sterile examination tools by autoclave class B were used. Clinical examination included Oral health and oral hygiene status, interarch distance, dimensions of the edentulous ridge, and soft tissue condition. Panoramic radiographs were taken to assess the condition of the patients' teeth and jawbone, as well as to detect any oral infections requiring treatment. Surgical procedures are performed to translocate the inferior alveolar nerve to provide a good space for implant insertion. All cases ahs undergone follow-up for post-surgical sensory disturbances.

02

Conditions studied

  • Sever Mandibular Bone Resorption
  • Sensory Defect
  • Implant Failure

Browse trials for

Keywords

  • Inferior Alveolar Nerve
  • Mandibular Atrophy
  • Dental Implant
  • Alveolar Ridge Resorption
03

In context

Bone Resorption

167 studies on the registry are indexed under Bone Resorption; 28 are open to participants now.

This study's enrollment of 9 is below the median of 24 across 146 interventional studies indexed under Bone Resorption.

Browse Bone Resorption studies →

Lead sponsor

University of Science and Technology, Yemen is the lead sponsor of 9 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

- All other patients

Exclusion criteria

Exclusion Criteria:

  • Patients with active infections, uncontrolled diabetes, history of radiotherapy, chemotherapy, or oral cancer surgery were excluded from this study
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
9 participants (actual)

Study arms

  • Experimental
    Dental implant group

    Device: Dental implant

Interventions

  • DeviceDental implant

    insertion of dental implants after surgical tranlocation of the inferior alveolar nerve.

06

What researchers measure

Primary outcomes

  1. Cone-beam Computed Tomography (CBCT)

    visualize the inferior alveolar canal (IAC) and assess the proximity of the implant to the nerve

    Time frame: The implant's success rate was determined by primary stability during insertion, assessed by ratchet, and then confirmed by X-ray. CBCTs were taken at 3 months and 4 months after implant insertion to check for marginal bone loss.

Secondary outcomes

  1. Subjective Function Score

    Patients rate their perceived sensory function relative to an unaffected area, providing a measure of functional impairment.

    Time frame: Neurosensory evaluation was carried out on the 1st and 7th postoperative day and every month thereafter for up to 6 months.

07

Study locations

1 site
  • University of Science and technology
    Aden, Yemen
08

References and documents

Publications

  • Hwaiti HS, Al-Rubidi YA, Al-Ashwal A, Al-Hadi Y, Al-Kibsi T, Al-Wesabi MA. Inferior alveolar nerve relocation and immediate dental implant placement in severely resorbed mandibles: a prospective clinical case series. BMC Oral Health. 2025 Dec 13;26(1):119. doi: 10.1186/s12903-025-07492-z. PubMed 41388273 ↗

Study documents

PDFs hosted by the registry, ClinicalTrials.gov.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Jun 2024 to primary completion in Apr 2025, 10 months.

Of 82 non-industry interventional studies with no phase under Bone Resorption, half reached primary completion within 23 months of starting (the median), counting those still running; a quarter within 12 and three quarters within 35. This study's 10 months is below that.

Counting every sponsor, half of 83 studies reached it within 23 months; a quarter within 12 and three quarters within 35.

How these figures are worked out, and which studies are left out of them.

Registered
Jul 22, 2025
First posted
Aug 5, 2025
StartActual
Jun 11, 2024
Primary completionActual
Apr 12, 2025
CompletionActual
May 20, 2025
Last update
Aug 5, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Aug 5, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07104994
Lead sponsor
University of Science and Technology, Yemen
Responsible party
Mohammed Ali Al-wesabi (Principal Investigator, University of Science and Technology, Yemen) — Principal investigator
First posted
Aug 5, 2025
Start date
Jun 11, 2024
Primary completion
Apr 12, 2025
Completion
May 20, 2025
Last update
Aug 5, 2025

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2025. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion