An interventional study of Low-fat, vegan diet in Type 2 Diabetes and Overweight and Obese Adults, sponsored by Physicians Committee for Responsible Medicine. Recruiting at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-17.
Sponsored by Physicians Committee for Responsible Medicine · Not applicable, Interventional, and Treatment
Among 10 studies in Diabetes Mellitus, Type 2 by Physicians Committee for Responsible Medicine — 2 open to participants now, 2 under way, none of them phase 3. Diabetes Mellitus, Type 2 · Physicians Committee for Responsible Medicine.
Among the 10 studies in Diabetes Mellitus, Type 2 by Physicians Committee for Responsible Medicine, this one is the 3rd largest by planned enrollment, is the only one that started in 2026, is one of 10 with no phase, and was the 10th registered.
10,371 studies on the registry are indexed under Diabetes Mellitus, Type 2; 1,406 are open to participants now.
Browse Diabetes Mellitus, Type 2 studies →2 of the 10 studies in Diabetes Mellitus, Type 2 by Physicians Committee for Responsible Medicine are open now, in 1 country. Recruiting first, the newest first:
Physicians Committee for Responsible Medicine · Sites in United States
By country, each count listing its studies:
Of the 883 Diabetes Mellitus, Type 2 studies recruiting now, 373 (42%) set no upper age limit and 384 (43%) stop at 75 or younger; 52 take children under 18; 203 take healthy volunteers.
This study: 18 Years and older · all sexes · no healthy volunteers.
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10 studies; the count open now beside each. This study's row is marked.
First in 2003; this study’s year is marked. 1 started in 2026.
This study's planned enrollment of 100 is above the median of 80 across 8,350 interventional studies indexed under Diabetes Mellitus, Type 2.
Median enrollment 38 across the 10 interventional studies. Of the 6 that completed or were terminated, 0 (0%) have results posted.
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Physicians Committee for Responsible Medicine is the lead sponsor of 32 studies on the registry; 4 are open to participants now.
None of the studies under way reaches primary completion within a year.
Among the 10 studies in Diabetes Mellitus, Type 2 by Physicians Committee for Responsible Medicine, from their registry updates:
Nothing recorded among them since 2026-09-25.
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This is an interventional study that will evaluate the feasibility, implementation, and efficacy of an online, 12-week, plant-based, nutrition education program in a community setting. Participants will meet with a physician and a registered dietitian once a week to learn about a plant-based diet and receive support and practical help in making the dietary changes. Body composition, blood sugar control, cholesterol levels, and food costs will be measured at the start and end of the study.
This is an interventional study that will evaluate the feasibility, implementation, and efficacy of an online, 12-week, plant-based, nutrition education program in a community setting. Participants will participate in weekly physician- and dietitian-lead group classes and will receive education about a plant-based diet as well as support and practical tips for implementing the dietary changes. Participants will receive baseline and 12 week assessments including a DXA scan to assess body composition, HbA1c, lipid panel, and a food cost analysis.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Age 19 or older in Nebraska and Alabama. Age 21 or older in Puerto Rico. Age 18 or older in all other states.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
All participants will be asked to follow a low-fat vegan diet. There are no other study arms or control group.
Behavioral: Low-fat, vegan diet
All participants will be asked to follow a low-fat vegan diet for the duration of the study. Participants will attend weekly classes where they we receive education and support.
The feasibility of an online plant-based weight loss program in the community setting.
Feasibility will be assessed by the number of total participants that enroll in the program and complete both baseline and final assessments.
Time frame: From baseline to the end of the intervention at 12 weeks.
Changes in glycated hemoglobin.
A1c will be measured using standard methods.
Time frame: From baseline to the end of the intervention at 12 weeks.
Changes in total and LDL cholesterol levels.
Total and LDL cholesterol levels will be measured using standard methods.
Time frame: From baseline to the end of the intervention at 12 weeks.
Changes in body composition.
Body composition will be measured by dual energy x-ray absorptometry (Lunar iDXA, GE Healthcare; Madison, WI) with Encore® 2005 v.9.15.010 software. The iDXA can measure body composition with low x-ray exposure and short scanning time. The iDXA unit will be calibrated daily using the GE Lunar calibration phantom, and a trained operator will perform all scans following standard protocol for participant positioning. The iDXA is equipped with the CoreScan module (GE Healthcare, Madison, WI), which can also provide an estimate of visceral adipose tissue volume and mass.
Time frame: From baseline to the end of the intervention at 12 weeks.
Food costs of a baseline diet and a low-fat plant-based diet.
Study participants will be asked to provide a food consumption record of three consecutive days (including two weekdays and one weekend day). Participants will be asked to include the specific brands, portions, names of retailers and restaurants where the food was purchased. A study team member will review the food record with the participants. We will then calculate the total cost of the food consumed during the 3-day period using cost data from the retailers' and restaurants' websites or by calling the specific restaurants and retailers.
Time frame: From baseline to the end of the intervention at 12 weeks.
Plan to share: No
Started Jan 2026 (actual). Primary completion is estimated for Oct 2028, 32 months after the start.
Of 2,066 non-industry interventional studies with no phase under Diabetes Mellitus, Type 2, half reached primary completion within 21 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 40. This study's planned 32 months is above that.
Counting every sponsor, half of 2,243 studies reached it within 21 months; a quarter within 10 and three quarters within 39.
How these figures are worked out, and which studies are left out of them.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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Physicians Committee for Responsible Medicine