An interventional study of Plant-based diet and Control Group in Overweight, Blood Pressure and Diabetes Mellitus, Type 2, sponsored by Physicians Committee for Responsible Medicine. Terminated at 1 site in United States. Open to participants aged 18 Years to 90 Years. Per ClinicalTrials.gov, last updated 2026-09-17.
Sponsored by Physicians Committee for Responsible Medicine · Not applicable, Interventional, and Supportive care
The proposed study seeks to test the effect of a plant-based dietary intervention on cardiovascular risk factors in police officers.
This study tests the hypotheses that a low-fat, plant-based (vegan) diet improves body weight, plasma lipid concentrations, blood pressure, and, in individuals with type 2 diabetes, glycemic control, that a low-fat, plant-based diet improves health-related quality of life as measured by the Medical Outcomes Study Short Form 36-Item Health Survey (SF-36), and that a low-fat, plant-based diet improves mood, as measured by the Center for Epidemiologic Studies Depression Scale-Revised (CESD-R).
3,670 studies on the registry are indexed under Overweight; 849 are open to participants now.
This study's planned enrollment of 20 is below the median of 73 across 3,175 interventional studies indexed under Overweight.
Browse Overweight studies →Physicians Committee for Responsible Medicine is the lead sponsor of 32 studies on the registry; 4 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Participants in the intervention group will follow a low-fat, plant-based diet for 14 weeks, and will attend nutrition classes in the form of a weekly support group.
Dietary Supplement: Plant-based diet
The control group will follow an unrestricted diet with no instruction.
Dietary Supplement: Control Group
Weekly instructions will be given to the participants in the intervention group about following vegan diet.
Also known as: Vegan Group
Unrestricted diet with no instruction.
Also known as: Control
Body Weight
body weight will be measured to the nearest 0.1 kg, using a digital scale.
Time frame: Changes in body weight from Baseline at 14 weeks
Plasma lipid concentrations
will be measured using the Olympus Cholesterol Reagent on Olympus Chemistry Analyzers to assess changes in plasma lipid concentrations.
Time frame: Changes in plasma lipid concentrations from Baseline at 14 weeks
Blood pressure
Blood pressure will be measured at each assessment
Time frame: Changes in blood pressure from Baseline at 14 weeks
Quality of Life and Mood
Measured by a Modified Health Assessment Questionnaire (MHAQ). The questionnaire measures the difficulty level of performing 8 different activities. A score of 0 = the activity can be performed without difficulty. A score of 3 = the activity cannot be performed. The MHAQ is calculated as the average of these scores.
Time frame: Change in quality of life from Baseline at 4 months
This study is terminated, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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Physicians Committee for Responsible Medicine