CClinicalTrials.gg
CompletedNCT07094022Updated Jul 30, 2025

Improvement and Safety of Nutrilite Protein MetX Pro on Weight Management in Overweight Individuals With Dyslipidemia

An interventional study of Nutrilite Protein MetX Pro and Placebo Product in Dyslipidemia and Obesity &Amp; Overweight, sponsored by Amway (China) R&D Center. Completed at 2 sites in China. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2025-07-30.

Sponsored by Amway (China) R&D Center · Not applicable, Interventional, and Supportive care

From the registry’s dates

  • Registered 4 months after the study started (first participant enrolled Mar 2025, registered Jul 2025).
Phase
Not applicable
Study type
Interventional
Enrollment
66
Allocation
Randomized
Ages
18 Years to 65 Years
Sex
All
01

Study summary

The goal of this randomized, double-blind, placebo-controlled, single center study is to evaluate the impact of Nutrilite Protein MetX Pro (the study product, a high-protein compound beverages supplemented with multiple plant proteins and apple extracts) on lipid profiles in the blood test in overweight individuals with dyslipidemia. The main question it aims to answer is:

- Does the intake of the study product improve the blood lipid profiles (TC,TG, LDL-C ) in terms of of overweight individuals with dyslipidemia?

Researchers will compare the product group to a placebo group to see whether the blood lipid profile is significantly better improved for participants in the product group.

Participants will:

  • take randomly assigned products 16g/each time, twice a day for 4 weeks
  • make four times site visits, once a week. Blood samples are collected for each visit, and Feces are collected for the first and last site visit.
02

Conditions studied

  • Dyslipidemia
  • Obesity &Amp; Overweight

Keywords

  • High-protein Compound Beverages
  • Nutrilite Protein MetX pro
03

In context

Dyslipidemias

1,073 studies on the registry are indexed under Dyslipidemias; 158 are open to participants now.

This study's enrollment of 66 is below the median of 99 across 842 interventional studies indexed under Dyslipidemias.

Browse Dyslipidemias studies →

Lead sponsor

Amway (China) R&D Center is the lead sponsor of 7 studies on the registry; 2 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Age: 18-65 years old
  • Overweight or obese participants, 40 with a BMI of 24-28 kg/m², and 40 participants with a BMI greater than 28. The percentage of male participants is ≥40%. And the lipid profile with the following characteristics:
  • TC (Total Cholesterol): 5.18-6.21 mmol/L;
  • TG(Triglyceride): 1.70-2.25 mmol/L;
  • LDL-C(Low-Density Lipoprotein Cholesterol): ≥ 3.4 mmol/L;
  • Agree to sign the informed consent form.

Exclusion criteria

Exclusion Criteria:

  • Pregnant or lactating women, those with allergic constitutions, or those allergic to this test sample.
  • Patients with severe diseases of the heart, liver, kidneys and hematopoietic system, as well as those with mental illness.
  • Those who have taken lipid-lowering drugs or the like in the past two weeks, which has affected their judgment of the results.
  • Patients with hyperlipidemia.
  • The researcher determined that the participant was not suitable for this trial.
05

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Investigator)
Enrollment
66 participants (actual)

Study arms

  • Active comparator
    Nutrilite Protein MetX Pro

    Nutrilite protein MetX pro, 460g per pack. Ingredients: Mung bean protein, chickpea protein, isomaltulose, rice (glutinous rice) protein, green apple concentrated juice powder, inulin, xanthan gum, guar gum, silicon dioxide, food flavoring.

    Dietary Supplement: Nutrilite Protein MetX Pro

  • Placebo comparator
    Placebo Product

    Placebo product , 460g per pack. Ingredient: Maltodextrin.

    Dietary Supplement: Placebo Product

Interventions

  • Dietary supplementNutrilite Protein MetX Pro

    A total of 4 cans (460 g/can) of study products (Nutrilite Protein MetX Pro) are distributed to each participant. Participants need to take 16g each time, twice a day, for 4 weeks.

  • Dietary supplementPlacebo Product

    A total of 4 cans (460 g/can) of placebo products are distributed to each participant. Participants need to take 16g each time, twice a day, for 4 weeks.

06

What researchers measure

Primary outcomes

  1. Lipid profile index-TC

    TC (Total Cholesterol) concentration level in the blood sample test: normal range 3-5.2 mmol/L; higher than 5.2 mmol/L is abnormal.

    Time frame: baseline day 0, day 28

  2. Lipid profile index-TG

    TG (Triglyceride) concentration level in the blood sample test : normal range 0\~1.7 mmol/L, higher than 1.7mmol/L is abnormal

    Time frame: baseline day 0, day 28

  3. Lipid profile index-LDL-C

    LDL-C(Low-Density Lipoprotein Cholesterol) concentration level in the blood sample test: normal range 0-3.1mmol/L, higher than 3.1 mmol/L is abnomal;

    Time frame: baseline day 0, day 28

Secondary outcomes

  1. Number of AE and SAE

    The number of AE(Adverse Event) and SAE(Serious Adverse Event) associated with study product, reported during the trial period.

    Time frame: baseline day 0, through day 28

07

Study locations

2 sites
  • Raison Biotech Group Shanghai Lab
    Shanghai, Shanghai Municipality, China
  • Jinhua Wenrong Hospital
    Jinhua, Zhejiang, China
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 30, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07094022
Lead sponsor
Amway (China) R&D Center
Responsible party
Sponsor
First posted
Jul 30, 2025
Start date
Mar 16, 2025
Primary completion
Jun 3, 2025
Completion
Jun 3, 2025
Last update
Jul 30, 2025

Study contacts

Dan Cao
principal investigator · Jinhua Wenrong Hospital

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion