An interventional study of Adaptive Cell Phone Support and Computer-Delivered Cell Phone Support in Medication Adherence, sponsored by Children's Hospital Los Angeles. Not yet recruiting at 1 site in United States. Open to participants aged 15 Years to 20 Years. Per ClinicalTrials.gov, last updated 2025-07-30.
Sponsored by Children's Hospital Los Angeles · Not applicable, Interventional, and Supportive care
The goal of this pilot clinical trial is to test a mobile health intervention for promoting medication adherence in a population of adolescents and young adults with chronic health conditions. The main question it aims to answer is:
-Is an adaptive intervention (personalizing the intensity of support based on patients' needs) efficacious for promoting medication adherence Researchers will compare the adaptive intervention to automated text message reminders see if the adaptive intervention shows stronger positive effects on medication adherence.
Plan to enroll 96 participants in this study, which is a sequential randomized trial.
221 studies on the registry are indexed under Medication Adherence; 108 are open to participants now.
This study's planned enrollment of 96 is below the median of 118 across 188 interventional studies indexed under Medication Adherence.
Browse Medication Adherence studies →Children's Hospital Los Angeles is the lead sponsor of 150 studies on the registry; 46 are open to participants now.
Of its 9 completed or terminated interventional studies of FDA-regulated products, 6 (67%) have results posted.
Counted across the registry records on this site, refreshed daily.
Inclusion Criteria:
There is no exclusion criteria.
Computer-delivered cell phone support (reminders, problem-solving, referrals to resources) and responsive human coaching (phone calls, test messages, in-app messaging) to improve medication adherence.
Behavioral: Adaptive Cell Phone Support · Behavioral: Computer-Delivered Cell Phone Support
Computer-delivered cell phone support (reminders, problem-solving, referrals to resources)
Behavioral: Computer-Delivered Cell Phone Support
Scheduled one-way text automated message reminders to take medication
Behavioral: Automated Text Reminders
Mobile health adherence promotion based on the supportive accountability model
Mobile health adherence promotion based on the supportive accountability model
Scheduled text reminder to take medication
Mean scores on the Mobile Health App Usability Questionnaire
Higher scores indicate greater ease with which users can use technology to achieve a particular goal; the minimum value of this questionnaire is 1 and the maximum value is 7.
Time frame: Baseline to 12 weeks
Total scores on the theoretical framework of acceptability questionnaire
Higher scores indicate a greater "extent to which people delivering or receiving a healthcare intervention consider it to be appropriate, based on anticipated or experienced cognitive and emotional responses to the intervention"; the minimum value of this questionnaire is 7 and the maximum value is 35.
Time frame: Baseline to 12 weeks
Total scores on the Visual Analogue Scale
Percentage of doses taken our of 100%; higher numbers indicate greater medication adherence. This scale presents participants with a line, marked 0 on the left and 100 on the right, and participants can drag a marker to the place on the line that best visually indicated their adherence.
Time frame: Baseline to 12 weeks
Total scores on Rollnick's Readiness Ruler
Higher scores on this measure indicate more motivation to take medication as prescribed; the minimum value of this questionnaire is 0 and the maximum value is 10.
Time frame: Baseline to 12 weeks
Total Transition Readiness scores on the Successful Transition to Adulthood with Therapeutic = Rx Questionnaire
Higher scores on extent to which patients are prepared to manage their health condition as adults, outside of the pediatric system; ; the minimum value of this questionnaire is 0 and the maximum value is 90.
Time frame: Baseline to 12 weeks
Plan to share: Yes — The data will include electronically-administered survey items assessing demographic characteristics, intervention usability, intervention acceptability, medication adherence, motivation for adherence, transition readiness skills, and allocation of treatment responsibility as well as medication regimen complexity data and pharmacy possession refill rates abstracted from the electronic medical chart, and behavioral engagement data collected via the Computerized Intervention Authoring Software.
No publications or documents are linked to this record.
This study is not yet recruiting, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.
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Children's Hospital Los Angeles