An interventional study of VR-based multi-dimensional intervention in Dementia, Sleepiness and Mental Health, sponsored by Hong Kong University of Science and Technology. Not yet recruiting. Open to participants aged 60 Years to 120 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-07-14.
Sponsored by Hong Kong University of Science and Technology · Not applicable, Interventional, and Treatment
Virtual Reality-based multi-dimensional intervention for cognition and well-being will be provided to older adults, with AI-agents. The digital health intervention include physical activity, gamification, cognitive trainings. Cognition, like memory, spatial function, sleepiness and mental health will be studied as outcomes.
In order to study the cognitive function and well-beings, qualitative methods (like questionnaires, interviews, focus groups) and quantitative methods (like ppg, ecg, eyetracker, eeg) will be used to collect data for analysis.
3,965 studies on the registry are indexed under Alzheimer Disease; 926 are open to participants now.
This study's planned enrollment of 60 is below the median of 70 across 3,019 interventional studies indexed under Alzheimer Disease.
Browse Alzheimer Disease studies →Hong Kong University of Science and Technology is the lead sponsor of 10 studies on the registry; 6 are open to participants now.
Compared within Alzheimer Disease, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Dementia. The counts are of registry records indexed under each term, refreshed daily. How we classify →
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
usual care
Provide VR-based multi-dimensional intervention
Device: VR-based multi-dimensional intervention
VR-based multi-dimensional intervention, including LLMs, AI-agents
Spatial cognition
mental rotation task,higher score means stronger spatial ability
Time frame: pre-intervention, after 4 weeks, 8 weeks, 12 weeks, 16 weeks, 3 months, 6 months, 1 year, 2 year, 3 year
Spatial cognition
money road map test, higher score means stronger spatial ability
Time frame: pre-intervention, after 4 weeks, 8 weeks, 12 weeks, 16 weeks, 3 months, 6 months, 1 year, 2 year, 3 year
Spatial cognition
building memory test, higher score means stronger spatial ability
Time frame: pre-intervention, after 4 weeks, 8 weeks, 12 weeks, 16 weeks, 3 months, 6 months, 1 year, 2 year, 3 year
Spatial cognition
corsi, , higher score means stronger spatial ability
Time frame: pre-intervention, after 4 weeks, 8 weeks, 12 weeks, 16 weeks, 3 months, 6 months, 1 year, 2 year, 3 year
Spatial cognition
digit span, higher score means stronger spatial ability
Time frame: pre-intervention, after 4 weeks, 8 weeks, 12 weeks, 16 weeks, 3 months, 6 months, 1 year, 2 year, 3 year
mental health
UCLA loneliness, higher score means more loneliness
Time frame: pre-intervention, after 4 weeks, 8 weeks, 12 weeks, 16 weeks, 3 months, 6 months, 1 year, 2 year, 3 year
mental health
Positive and Negative Affect Schedule , 2 subscare, one is for positive, higher score means more positive affects, one is for negative, higher score mean more negetive affects
Time frame: pre-intervention, after 4 weeks, 8 weeks, 12 weeks, 16 weeks, 3 months, 6 months, 1 year, 2 year, 3 year
mental health
The World Health Organization-Five Well-Being Index (WHO-5), higher score means better mental well-being
Time frame: pre-intervention, after 4 weeks, 8 weeks, 12 weeks, 16 weeks, 3 months, 6 months, 1 year, 2 year, 3 year
Sleepiness
Effects on sleepiness, measured by The Pittsburgh Sleep Quality Index (PSQI)
Time frame: pre-intervention, after 4 weeks, 8 weeks, 12 weeks, 16 weeks, 3 months, 6 months, 1 year, 2 year, 3 year
No study locations are listed for this record.
Plan to share: No — Personal identity and health metrics are restricted and confidentially saved.
No publications or documents are linked to this record.
Start is estimated for Jul 2025; primary completion for Jun 2028, 35 months later.
Of 882 non-industry interventional studies with no phase under Alzheimer Disease, half reached primary completion within 30 months of starting (the median), counting those still running; a quarter within 15 and three quarters within 51. This study's planned 35 months is above that.
Counting every sponsor, half of 959 studies reached it within 29 months; a quarter within 15 and three quarters within 51.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.
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Hong Kong University of Science and Technology