CClinicalTrials.gg
CompletedNCT07044258Updated Jun 29, 2025

Trans-tarsal Stair-step Lateral Extension of the Transconjunctival Approach

An interventional study of trans-tarsal stair-step lateral extension of the transconjunctival approach and transconjunctival approach in Zygomatic Fractures and Lower Eyelid Entropion, sponsored by Alexandria University. Completed at 1 site in Egypt. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-06-29.

Sponsored by Alexandria University · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

Open reduction and internal fixation of orbito-zygomaticomaxillary complex (OMC) fractures has challenging impact on the selection of suitable surgical approach to orbital and zygomatic skeleton. Precise repair of the OMC fractures needs a quite understanding of the regional anatomy, precise diagnosis, an accessible exposure and an accurate rigid fixation of fracture to restore the normal form. The esthetic results are one of the most important requirements for this incision in the facial fracture reduction. conventional approaches to the infraorbital rim/orbital floor include (subciliary mid lower eyelid, or subtarsal) and infraorbital incisions. A thorough understanding of each incisional technique requires an appreciation of the relevant anatomy putting in considerations the risk of associated complications. Transconjuctival incision has a lot of advantages, among which is the production of non-visible scar with low incidence of post -operative ectropion and limited access. Trans-tarsal stair-step lateral extension of the transconjunctival approach provides excellent surgical exposure of OMC fractures avoiding the use of a second incision in the area of zygomatic frontal suture. This technique provides good exposure and excellent esthetics.

the aim of this study is to compare Trans-tarsal Stair-Step Lateral Extension of the Transconjunctival approach with transconjunctival approach in the management of orbital and zygomaticomaxillary complex fractures.

Read the detailed description

This study will be made on twenty patients who will undergo fracture repair of the zygomaticomaxillary complex. Post- operative patient evaluation will be performed with specific attention paid towards accessibility, the exposure duration (time from incision till exposure of the field), esthetic appearance, post- operative pain, postoperative edema, orbital movement, wound healing, scarring, infra orbital nerve sensation and the post- operative ocular complications such as ectropion, entropion, enophthalmos, scleral show and corneal abrasion. Post- operative clinical examinations along with radiographic examination will be done to evaluate the position of zygoma and determine the adequacy of fracture reduction.

02

Conditions studied

  • Zygomatic Fractures
  • Lower Eyelid Entropion

Keywords

  • Orbito-zygomaticomaxillary Fracture
  • Transconjunctival Incision
  • Lower eyelid
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  1. Patients with OMC fractures that require open reduction with internal fixation.
  2. Patients with orbital wall defects.
  3. Patients with blow out fractures.
  4. Adult patient between 18 and 60 years with no gender predilections.

Exclusion criteria

Exclusion Criteria:

  1. Existing lacerations in the inferior and lateral periorbital regions.
  2. Comminuted fracture with bone loss.
  3. Existence of infection at the fracture line.
  4. Presence of acute or chronic conjunctival diseases.
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
20 participants (actual)

Study arms

  • Active comparator
    trans-tarsal stair-step lateral extension of the transconjunctival approach

    patients presented with oribto-zygomaticomaxillary complex fractures that requires open reduction and internal fixation via trans-tarsal stair-step lateral extension of the transconjunctival approach

    Procedure: trans-tarsal stair-step lateral extension of the transconjunctival approach

  • Experimental
    transconjunctival approach

    patients presented with oribto-zygomaticomaxillary complex fractures that requires open reduction and internal fixation via transconjunctival approach

    Procedure: transconjunctival approach

Interventions

  • Proceduretrans-tarsal stair-step lateral extension of the transconjunctival approach

    patients presented with oribto-zygomaticomaxillary complex fractures that requires open reduction and internal fixation via trans-tarsal stair-step lateral extension of the transconjunctival approach

  • Proceduretransconjunctival approach

    patients presented with oribto-zygomaticomaxillary complex fractures that requires open reduction and internal fixation via trans-tarsal stair-step lateral extension of the transconjunctival approach

05

What researchers measure

Primary outcomes

  1. exposure duration

    The time taken between performing the incision till exposure of the field will be recorded using a stopwatch.

    Time frame: During the surgery

Secondary outcomes

  1. postoperative edema

    The postoperative edema will be categorized subjectively into mild (just noticeable), mild to moderate (more obvious edema without occlusion of palpebral fissure), moderate to severe (edema partially occluding palpebral fissure), and severe (edema totally occluding palpebral fissure).

    Time frame: 1.5 month

06

Study locations

1 site
  • Faculty of Dentistry, Alexandria University
    Alexandria, Alexandria Governorate 21523, Egypt
07

References and documents

Individual participant data

Plan to share: Yes — all data will be de-identified to protect the participant data. patients signed an informed consent for the use of their medical records and data for study

Supporting information: Sap

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT07044258
Lead sponsor
Alexandria University
Responsible party
Sponsor
First posted
Jun 29, 2025
Start date
Oct 1, 2024
Primary completion
Mar 30, 2025
Completion
Jun 15, 2025
Last update
Jun 29, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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