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CompletedNCT07026721Updated Jun 18, 2025

Comparative Analysis of RIRS Scoring System and Resorlu Unsal Stone Score (RUSS) for Predicting Stone-free Rate After Retrograde Intrarenal Surgery

An observational study in Renal Stones, sponsored by Maharajgunj Medical Campus. Completed at 1 site in Nepal. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-06-18.

Sponsored by Maharajgunj Medical Campus · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
60
Ages
18 Years and older
Sex
All
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Study summary

Several studies have investigated the use of scoring systems for predicting stone-free rates after RIRS. Previous research has evaluated the RIRS Scoring System, RUSS, and other similar systems in different patient populations. This study was conducted to compare RIRS scoring system and Resorlu Unsal Stone Score (RUSS) for predicting stone free rate.

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Conditions studied

  • Renal Stones

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In context

Nephrolithiasis

324 studies on the registry are indexed under Nephrolithiasis; 90 are open to participants now.

This study's enrollment of 60 is below the median of 100 across 57 observational studies indexed under Nephrolithiasis.

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Lead sponsor

Maharajgunj Medical Campus is the lead sponsor of 8 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

All the patients with renal calculi undergoing RIRS.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • patients more than 18 years of age undergoing RIRS for renal stone
  • providing informed written consent

Exclusion criteria

Exclusion Criteria:

  • Previous renal and ureteric surgeries
  • coexisting bladder, ureteral stone
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
60 participants (actual)
Patient registry
No

Interventions

  • ProcedureRetrograde intrarenal surgery (RIRS)

    The intervention involves Retrograde Intrarenal Surgery (RIRS) performed using a flexible ureteroscope to access the renal collecting system via a retrograde (urethra → bladder → ureter → kidney) approach. Stones are fragmented using a holmium:YAG laser, with or without the use of a ureteral access sheath, depending on the case. What distinguishes this intervention from others is the integration of preoperative scoring systems-specifically the RIRS Scoring System and the Resorlu Unsal Stone Score (RUSS)-to predict stone-free outcomes and guide case selection and surgical planning. Additionally, all procedures are performed by experienced endourologists following a standardized protocol, including consistent patient positioning, anesthesia, access technique, and post-operative imaging at defined intervals to assess outcomes.

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What researchers measure

Primary outcomes

  1. Correlation between the RIRS Scoring System and stone-free rate after Retrograde Intrarenal Surgery (RIRS), assessed using CT KUB

    Time frame: 12 months

  2. Correlation between the Resorlu-Unsal Stone Score (RUSS) and stone-free rate after Retrograde Intrarenal Surgery (RIRS), assessed using CT KUB

    Time frame: 12 months

Secondary outcomes

  1. Stone Burden as a Predictor of Stone-Free Rate After RIRS

    Correlation between stone burden (mm²) and stone-free rate after Retrograde Intrarenal Surgery (RIRS

    Time frame: Preoperative assessment and 1 month postoperatively for stone-free status

  2. Stone Density as a Predictor of Stone-Free Rate After RIRS

    Correlation between stone density (Hounsfield Units, HU) and stone-free rate after RIRS

    Time frame: Preoperative assessment and 1 month postoperatively for stone-free status

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Study locations

1 site
  • Department of Urology and Kidney Transplant Surgery, Tribhuvan University Teaching Hospital (TUTH), Maharajgunj, Kathmandu, Nepal
    Kathmandu, Bagmati 44600, Nepal
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References and documents

Individual participant data

Plan to share: Yes

Supporting information: Study protocol

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 18, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07026721
Lead sponsor
Maharajgunj Medical Campus
Responsible party
Prajjwol Luitel (Principal Investigator, Maharajgunj Medical Campus) — Principal investigator
First posted
Jun 18, 2025
Start date
Jan 1, 2024
Primary completion
Dec 27, 2024
Completion
Dec 29, 2024
Last update
Jun 18, 2025

Study contacts

Saro Prajapati, MBBS, MS
study director · Department of General Surgery Maharajgunj Medical Campus Institute of Medicine, Tribhuvan University

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2024. You cannot join it, but the record below documents what was studied.

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