An observational study in Gastrointestinal, sponsored by Maharajgunj Medical Campus. Completed at 1 site in Nepal. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-07-28.
Sponsored by Maharajgunj Medical Campus · Observational
Recent studies from Asia have reported a wide variation in the incidence of deep vein thrombosis (DVT), ranging from 5% to 50% in patients undergoing major abdominal surgery. However, data specific to the Nepalese population remains unavailable. This study aims to evaluate current thromboprophylaxis practices and determine the incidence of DVT in Nepalese adults undergoing gastrointestinal and hepatobiliary surgery.
Maharajgunj Medical Campus is the lead sponsor of 8 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
The study population consisted of adult patients aged >18 years who underwent major gastrointestinal or hepatobiliary surgery under general anesthesia at a tertiary referral center in Nepal. Patients were identified retrospectively through departmental audit records from the Department of Surgical Gastroenterology between October 2021 and April 2024. Major surgery was defined as any operative intervention involving the abdominal or hepatobiliary region requiring general anesthesia. Surgical procedures were categorized by organ system into upper gastrointestinal, hepatopancreatobiliary (HPB), colorectal, and other (e.g., small intestine, retroperitoneum, abdominal wall). Patients with a recent history of venous thromboembolism (VTE), known hypercoagulable conditions, atrial fibrillation, ongoing cancer therapy, pregnancy, or incomplete clinical data were excluded from the study. Data collected included demographic, clinical, intraoperative, and postoperative variables relevant to thromb
Exclusion Criteria:
Procedure: major gastrointestinal or hepatobiliary surgery under general anesthesia
major gastrointestinal or hepatobiliary surgery under general anesthesia
Use of Thromboprophylaxis and Incidence of DVT in Major GI and Hepatobiliary Surgeries
This outcome assesses the proportion of patients receiving appropriate thromboprophylaxis, as well as the incidence of deep vein thrombosis (DVT) among individuals undergoing major gastrointestinal and hepatobiliary surgeries. Data will be collected to evaluate adherence to prophylaxis guidelines and to determine the effectiveness of thromboprophylactic measures in preventing DVT in this surgical population.
Time frame: From date of surgery until hospital discharge or up to 30 days postoperatively, whichever occurs first
Plan to share: Yes — De-identified individual participant data (IPD) related to demographic characteristics, surgical details, thromboprophylaxis use, and DVT outcomes will be shared. This includes preoperative, intraoperative, and postoperative variables as collected in the study.
Supporting information: Sap, Analytic code
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This study is completed, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.
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