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CompletedNCT07006376Updated Mar 25, 2026

Thoracolumbar Fascia Thickness in Patients With Parkinson's Disease

An observational study in Parkinson Disease, sponsored by Ankara University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 55 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-03-25.

Sponsored by Ankara University · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
80
Ages
55 Years to 80 Years
Sex
All
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Study summary

The aim of this study is to examine thoracolumbar fascia thickness, trunk flexibility, trunk control and upper extremity skills in Parkinson's disease patients. Patients between the ages of 55-80 who have been diagnosed with Parkinson's disease by a neurologist and healthy individuals with similar demographic characteristics will be included in the study as a control group. Demographic information of the individuals will be recorded and clinical evaluations will be made. Staging of Parkinson's patients will be done with the Modified Hoehn and Yahr Scale (MHRS), and disease severity will be done with the Unified Parkinson's Disease Rating Scale (UPDRS). Thoracolumbar fascia thickness of individuals in both groups will be evaluated with ultrasonography, trunk flexibility with the Active Trunk Range of Motion Assessment and Sit-Reach test, trunk functions with the Trunk Impairment Scale, and manual skills with the Purdue Pegboard Test.

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Conditions studied

  • Parkinson Disease

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03

In context

Parkinson Disease

4,487 studies on the registry are indexed under Parkinson Disease; 1,082 are open to participants now.

This study's enrollment of 80 is below the median of 96 across 1,057 observational studies indexed under Parkinson Disease.

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Lead sponsor

Ankara University is the lead sponsor of 312 studies on the registry; 68 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
55 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Patients with Parkinson's Disease

Inclusion criteria

  • Age between 50 and 80
  • Mini Mental State Examination (MMSE) score between 24 and 30
  • Diagnosed with Parkinson's by a neurologist
  • MH\&Y stage 2-3

Exclusion criteria

Exclusion Criteria:

  • Inability to communicate verbally
  • Use of walking aids
  • Elderly people with severe visual impairment, neurological disorders and/or congestive heart failure
  • Older adults in whom exercise is not recommended.
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
80 participants (actual)
Patient registry
No

Groups and cohorts

  • Study Group

    Patients with Parkinson's Disease

  • Control Group

    Healthy individuals with similar demographic characteristics

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What researchers measure

Primary outcomes

  1. Ultrasonography Measurement

    The thickness of the Thoracolumbar Fascia will be measured by ultrasonography at the level of the L3 lumbar vertebra and using a predefined standard protocol.

    Time frame: Baseline

  2. Range of Motion Assessment

    Active trunk ranges of motion will be assessed during flexion/extension, rotation, and lateral flexion using a universal goniometer.

    Time frame: Baseline

  3. Sit and Reach Test

    For this test, a tape measure will be fixed to a table at the exact level of the subjects' feet. Subjects will sit in front of the table with bare feet and legs straight. Then, they will slowly extend forward as far as possible, keeping their hands together and without bending their knees. During this extension, attention will be paid to the subjects' straight backs and to avoid sudden movements.

    Time frame: Baseline

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Study locations

1 site
  • Atılım University
    Ankara, Turkey (Türkiye)
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References and documents

Publications

  • De Coninck K, Hambly K, Dickinson JW, Passfield L. Measuring the morphological characteristics of thoracolumbar fascia in ultrasound images: an inter-rater reliability study. BMC Musculoskelet Disord. 2018 Jun 1;19(1):180. doi: 10.1186/s12891-018-2088-5. PubMed 29859080 ↗
  • Yerli S, Yinanc SB, Yagci G, Erbahceci F, Ozcakar L. Thoracolumbar fascia and chronic low back pain in idiopathic lumbar scoliosis: an ultrasonographic study. Eur Spine J. 2024 Jun;33(6):2469-2475. doi: 10.1007/s00586-024-08266-x. Epub 2024 Apr 23. PubMed 38653872 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 25, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07006376
Lead sponsor
Ankara University
Responsible party
Büşra Seçkinoğulları Korkusuz (Principal Investigator, Ankara University) — Principal investigator
First posted
Jun 5, 2025
Start date
Jun 11, 2025
Primary completion
Aug 20, 2025
Completion
Sep 20, 2025
Last update
Mar 25, 2026

Study contacts

Ayla Fil Balkan, Assoc Prof
study chair · Hacettepe University
Gül Yalçın Çakmaklı, Assoc Prof
study chair · Hacettepe University
Süleyman Korkusuz, Assist.Prof
study chair · Atılım University
Büşra Seçkinoğulları Korkusuz, PhD
principal investigator · Ankara University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.

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