A Phase 3 interventional study of Chlorhexidine and Chlorhexidine in Chlorhexidine, sponsored by Hospital Universitario Evangelico de Curitiba. Completed at 1 site in Brazil. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-06-03.
Sponsored by Hospital Universitario Evangelico de Curitiba · Phase 3, Interventional, and Prevention
You are being invited as a volunteer to participate in the study "Dressing impregnated with chlorhexidine and vancomycin for the prophylaxis of central venous catheter-related infections." The objective is to evaluate the incidence of bloodstream infection related to the catheter in ICU patients with central venous catheters (CVC), using dressings impregnated or not with chlorhexidine/vancomycin. We believe this study is important as it aims to evaluate a new dressing method intended to reduce bloodstream-related infections.
107 studies on the registry are indexed under Catheter-Related Infections; 16 are open to participants now.
This study's enrollment of 516 is above the median of 150 across 76 interventional studies indexed under Catheter-Related Infections.
Browse Catheter-Related Infections studies →Hospital Universitario Evangelico de Curitiba is the lead sponsor of 4 studies on the registry; 2 are open to participants now.
Counted across the registry records on this site, refreshed daily.
IInclusion criteria included: age over 18 years, admitted to the ICU, need for a CVC placed in the ICU by the trained team, use of the CVC for a period exceeding 72 hours, and intact skin in the area of contact with the dressing. CVC inserted outside the ICU and need for two CVCs in the same patient simultaneously were exclusion criteria. A subsequent CVC could not be randomized. Other infections were not excluded during the evaluation. Only short-term CVC were evaluated (long-term and hemodialysis were excluded).
Impregnated
Device: Chlorhexidine
COmmon dressing
Device: Chlorhexidine
dressing impregnated
Also known as: Impregnated dressing
COmmon dressing
Also known as: COmmon dressing
Infection
CRBSI was the primary endpoint
Time frame: 30 days
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in May 2025. You cannot join it, but the record below documents what was studied.
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Hospital Universitario Evangelico de Curitiba