An interventional study of ADHINCRA Program in Hypertension and High Blood Pressure, sponsored by Johns Hopkins University. Recruiting at 17 sites in 3 countries. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2026-01-14.
Sponsored by Johns Hopkins University · Not applicable, Interventional, and Health services research
The ADHINCRA Program is a bundle of multilevel evidence-based interventions that address multiple predictors of controlled hypertension, including patient-, provider-, and health system-level factors. The successful implementation of the ADHINCRA program will provide a rigorous and scalable model for improving hypertension control in Africa, which would ultimately reduce the risk of cardiovascular disease, stroke and kidney disease.
6,114 studies on the registry are indexed under Hypertension; 912 are open to participants now.
This study's planned enrollment of 800 is above the median of 100 across 4,575 interventional studies indexed under Hypertension.
Browse Hypertension studies →Johns Hopkins University is the lead sponsor of 1,815 studies on the registry; 315 are open to participants now.
Of its 208 completed or terminated interventional studies of FDA-regulated products, 144 (69%) have results posted.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
The study doctor’s estimate of how long someone is likely to live. Criteria use it so that people can stay in the study long enough for it to answer its question.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Life expectancy
The study doctor’s estimate of how long someone is likely to live. Criteria use it so that people can stay in the study long enough for it to answer its question.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
This cohort will be the first to participate in the ADHINCRA Program, which includes home blood pressure monitoring, an mHealth app, nurse-led lifestyle counselling and treatment with a simplified hypertension control protocol.
Behavioral: ADHINCRA Program
This cohort will begin the ADHINCRA Program 3 months after Cohort 1.
Behavioral: ADHINCRA Program
This cohort will begin the ADHINCRA Program 6 months after Cohort 1.
Behavioral: ADHINCRA Program
This cohort will begin the ADHINCRA Program 9 months after Cohort 1.
Behavioral: ADHINCRA Program
The ADHINCRA Program is a nurse-led intervention that includes the use of home blood pressure monitoring, a mobile health app, lifestyle counselling, and a simplified hypertension treatment protocol to achieve blood pressure control among people diagnosed with hypertension.
Number of participants with systolic blood pressure <140 mmHg
Blood pressure control among participants defined as systolic blood pressure \<140 mmHg
Time frame: Baseline and 12 months post-randomization
Number of participants with diastolic blood pressure <90 mmHg
Blood pressure control as assessed by diastolic blood pressure \<90mmHg
Time frame: Baseline, 12 months, 24 months post-randomization
Medication adherence as assessed by Hill-Bone Medication Adherence Scale
Adherence to medications prescribed per the ADHINCRA Program treatment protocol. The total score ranges from 14 - 56. Higher score is better adherence.
Time frame: Baseline, 12 months, 24 months post-randomization
Percentage of sites that adopt and maintain the intervention as assessed by the Pragmatic Robust Implementation and Sustainability Model
Use the Pragmatic Robust Implementation and Sustainability Model (PRISM) to evaluate the reach, adoption, maintenance of the ADHINCRA Program
Time frame: Baseline, 12 months, 24 months post-randomization
Difference in cost of intervention compared to usual care as assessed by the Pragmatic Robust Implementation and Sustainability Model
Use the Pragmatic Robust Implementation and Sustainability Model (PRISM) to evaluate the cost-effectiveness of the ADHINCRA Program
Time frame: Baseline, 12 months, 24 months post-randomization
Not enrolling at this site.
Plan to share: No
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