An observational study in Anterior Cruciate Ligament Injury, Knee Injury and Ligament Reconstruction, sponsored by Abdirahman Hassan Omar. Not yet recruiting at 1 site in Denmark. Open to participants aged 15 Years to 50 Years. Per ClinicalTrials.gov, last updated 2025-05-20.
Sponsored by Abdirahman Hassan Omar · Observational
This study looks at two different types of tendon (tissue) used in knee surgery to repair a torn anterior cruciate ligament (ACL), which is a common injury in active people. The two types are taken from different muscles in the thigh: one from the front (quadriceps) and one from the back (semitendinosus). We will use information already collected in a national health registry to see how patients recover after surgery. The study will compare knee function, activity level, and how often patients need another operation.
This is a retrospective observational cohort study based on data from the Danish Knee Ligament Reconstruction Registry (DKRR). The study includes patients who underwent primary ACL reconstruction using either a quadriceps tendon graft (with or without a bone block) or a quadrupled semitendinosus tendon graft. The primary outcome measures are the Knee Injury and Osteoarthritis Outcome Score (KOOS) and the Tegner Activity Scale. Secondary outcomes include reoperation rates, postoperative complications, and patient satisfaction. All available demographic, operative, and patient-reported outcome data will be analyzed. Multivariable regression will be used to adjust for confounders such as age, sex, BMI, time from injury to surgery, and surgeon volume. The study is exempt from ethical approval under Danish law, and data will be handled in compliance with GDPR.
521 studies on the registry are indexed under Anterior Cruciate Ligament Injuries; 169 are open to participants now.
This study's planned enrollment of 2,500 is above the median of 96 across 131 observational studies indexed under Anterior Cruciate Ligament Injuries.
Browse Anterior Cruciate Ligament Injuries studies →This is the only study on the registry with Abdirahman Hassan Omar as lead sponsor.
Counted across the registry records on this site, refreshed daily.
Patients registered in the Danish Knee Ligament Reconstruction Registry (DKRR) who underwent primary anterior cruciate ligament reconstruction using either a quadriceps tendon graft or a semitendinosus tendon graft. All included patients have completed at least one year of follow-up and patient-reported outcome measures. The population consists of physically active individuals aged 15 to 50 years.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Patients who underwent primary ACL reconstruction using a quadriceps tendon autograft, with or without a bone block. Data are derived retrospectively from the Danish Knee Ligament Reconstruction Registry (DKRR).
Patients who underwent primary ACL reconstruction using a quadrupled semitendinosus tendon autograft. Data are derived retrospectively from the Danish Knee Ligament Reconstruction Registry (DKRR).
The Knee Injury and Osteoarthritis Outcome Score (KOOS)
The Knee Injury and Osteoarthritis Outcome Score (KOOS) evaluates pain, symptoms, daily living, sport/recreation, and knee-related quality of life. Metric type: continuous PROM-based subscale score Method of measurement: Self reported questionnaire
Time frame: At minimum 1 year follow up postoperatively
Tegner Activity Score
Assesses patients' level of physical activity before injury and at follow-up. Metric type: Scale from 0-10, where 0 is no physical activity caused by knee problems and 10 is an ability to compete in elite level sport like soccer and ski. Method of measurement: Tegner scale, self reported
Time frame: Minimum 1 year follow up postoperatively.
Re-operation rate
Incidence of surgical re-intervention after primary ACL reconstruction. Method of measurement: Registry recorded re-operations in DKRR
Time frame: Within 1 year of surgery
Postoperative complications
Frequency of postoperative complications such as infection, stiffness, or graft failure. Metric type: Occurrence of postoperative complications Method of measurement: Clinically reported and registry documented complications in DKRR
Time frame: Within 1 year after surgery
Patient satisfaction
Overall patient satisfaction with surgical outcome, if available in registry. Metric type: PROM's available from the DKRR Method of measurement: Patient reported satisfaction score.
Time frame: 1 year follow up
Plan to share: Undecided
No publications or documents are linked to this record.
Start is estimated for Jun 2025; primary completion for Sep 2025, 3 months later.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in May 2025. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Anterior Cruciate Ligament Injuries →