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CompletedNCT06950411Spinal cordUpdated Apr 30, 2025

Validation of AI Lumbar Spine Anatomy Measureing Function

An observational study in Spinal Cord Compression, sponsored by RadiRad Co., Ltd.. Completed at 1 site in Taiwan. Open to participants aged 22 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-04-30.

Sponsored by RadiRad Co., Ltd. · Observational

Study type
Observational
Model
Other
Time perspective
Prospective
Enrollment
150
Ages
22 Years to 75 Years
Sex
All
01

Study summary

Spinal degeneration and its associated clinical diseases are common ailments in aging societies. With the advent of a super-aging society, the importance of assistive technologies for spinal image interpretation is increasingly significant to enhance care efficiency and reduce medical personnel expenditure. Recently, due to the rapid development of artificial intelligence (AI) algorithm, AI-based computer-assisted detection (CADe) devices gradiually become a convenient method for spinal anatomy measurement. However, the accuracy of these devices has not been fully established. This study aims to validate the performance of RadiSpine (an application program) in spinal anatomy segmentation and measurement.

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Conditions studied

  • Spinal Cord Compression

Keywords

  • Artificial Intelligence(AI) Algorithm Spinal anatomy
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Who can participate

Ages eligible
22 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

The subjects should be aged 20 or older and younger than 75, with an equal gender distribution of 50% male and 50% female. From this group, 150 subjects with reasonable datavalues will be selected, with a requirement that at least 30% of them are male and at least 30% are female.

Inclusion criteria

The subjects should be aged 20 or older and younger than 75, with an equal gender distribution of 50% male and 50% female. From this group, 150 subjects with reasonable datavalues will be selected, with a requirement that at least 30% of them are male and at least 30% are female.

Exclusion criteria

Exclusion Criteria:

  1. With history of spinal surgery
  2. Spinal trauma
  3. Spinal osteoporosis
  4. Spinal metastasis or infection
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Study design

Observational model
Other
Time perspective
Prospective
Enrollment
150 participants (actual)
Patient registry
No
05

What researchers measure

Primary outcomes

  1. Segmentation accuracy (Mean)

    The minimum Mean Dice Coefficient (MDC), defined as the lower limit of the 95% confidence interval (CI) for MDC, is above a predetermined allowable limit equal to 0.8

    Time frame: 30 mins per individual

Secondary outcomes

  1. Measurement accuracy

    The maximum Mean Absolute Error (MAE), defined as the upper limit of the 95% CI for MAE, is below a predetermined allowable error limit equal to 2 mm

    Time frame: 30 mins per individual

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Study locations

1 site
  • Taipei Veterans General Hospital
    Taipei, 112, Taiwan
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Registry details

Key details

Study ID
NCT06950411
Lead sponsor
RadiRad Co., Ltd.
Collaborators
Taipei Veterans General Hospital, Taiwan
Responsible party
Sponsor
First posted
Apr 30, 2025
Start date
Sep 12, 2024
Primary completion
Mar 31, 2025
Completion
Mar 31, 2025
Last update
Apr 30, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Apr 2025. You cannot join it, but the record below documents what was studied.

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