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CompletedNCT06944366Updated Jun 22, 2026

Comparing Exposure v Imagery Rescripting in People With OCD: a SCED

An interventional study of Imagery intervention in Obsessive-Compulsive Disorder (OCD), sponsored by King's College London. Completed at 1 site in United Kingdom. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-06-22.

Sponsored by King's College London · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 7 months after the study started (first participant enrolled Aug 2024, registered Apr 2025).
Phase
Not applicable
Study type
Interventional
Enrollment
6
Allocation
Randomized
Ages
18 Years and older
Sex
All
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Study summary

Individuals with OCD may experience intrusive future orientated thoughts and images, which are extremely distressing and interfering in life. This project aims to explore whether imagery rescripting or exposure may be a more effective intervention for individuals with OCD experiencing such images.

02

Conditions studied

  • Obsessive-Compulsive Disorder (OCD)
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In context

Obsessive-Compulsive Disorder

606 studies on the registry are indexed under Obsessive-Compulsive Disorder; 160 are open to participants now.

This study's enrollment of 6 is below the median of 45 across 492 interventional studies indexed under Obsessive-Compulsive Disorder.

Browse Obsessive-Compulsive Disorder studies →

Lead sponsor

King's College London is the lead sponsor of 506 studies on the registry; 125 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • 18 years or over
  • Main diagnosis of OCD (assessed by the Structured Clinical Interview for ICD11)
  • Must report future orientated images that are distressing and ego-dystonic

Exclusion criteria

Exclusion Criteria:

  • Psychosis, bipolar disorder, or trauma disorder
  • Current stimulant or hallucinogenic misuse, alcohol or substance misuse or dependence
  • Intellectual disability, dementia, serious cognitive impairment, or organic brain disorder
  • Personality Disorder as the main problem
  • Active suicidality
  • Concurrent engagement in other psychotherapy
  • A patient may be taking anti-depressant medication so long as the dose has been stable for 6 weeks and there is no plan to increase the dose.
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Crossover assignment
Masking
None (open label)
Enrollment
6 participants (actual)

Study arms

  • Experimental
    ImR

    ImR completed as first intervention then ImExp

    Other: Imagery intervention

  • Experimental
    ImExp

    ImExp completed then ImR

    Other: Imagery intervention

Interventions

  • OtherImagery intervention

    Imagery rescripting or imaginal exposure

06

What researchers measure

Primary outcomes

  1. Obsessive Compulsive Inventory (OCI).

    A 42-item self-report scale to assess the severity and type of OCD symptoms; the OCI uses a 5-point Likert scale ranging from 0 (not at all) to 4 (extremely) and measures distress relating to 7 different subscales (washing, checking, doubting, ordering, obsessions, hoarding, and mental neutralizing). The total summed score of all items ranged between zero and 168. This measure will be completed at the beginning and end of each phase. Higher scores suggest more severe OCD symptomology.

    Time frame: From the start of treatment until the end of treatment at 12 weeks.

  2. Yale-Brown Obsessive-Compulsive scale (Y-BOCS).

    A 10-item self-rated scale used to measure the severity of obsessive-compulsive symptoms and response to treatment; each item is scored from 0 (no symptoms) to 4 (extreme symptoms), with a total ranging from zero to 40. It will be completed at the beginning and end of each phase. Higher scores suggest more severe OCD symptomatology.

    Time frame: From the start of treatment until the end of treatment at 12 weeks.

  3. The Impact of Future Events Scale (IFES).

    A 24-item self-rating scale used to measure the impact of intrusive prospective, personally relevant imagery. Each item is scored from 0 (no symptoms) to 4 (extreme symptoms), with a total ranging from zero to 96. Higher scores indicate greater symptomatology. This will be completed at the beginning and end of each phase.

    Time frame: From the start of treatment until the end of treatment at 12 weeks.

  4. The Florida Obsessive Compulsive Inventory (FOCI).

    Designed to measure the severity and frequency of obsessive-compulsive symptoms in individuals. The severity scale (Part B) of the FOCI was used in the project. Part B is a 5-item self-rating scale used to measure the frequency, severity, and impact of obsessive-compulsive symptoms; each item is scored from 0 (no symptoms) to 4 (extreme symptoms), with a total ranging from zero to 20. Higher scores indicate greater symptomology.

    Time frame: From the start of treatment until the end of treatment at 12 weeks.

  5. Visual Analogue Scales (VAS).

    Five daily self-report scales to be designed by the researchers using fixed scale (0=not at all; 10=extremely) answers to measure the following: Frequency of future orientated imagery Severity of future orientated imagery Vividness of future orientated imagery Degree of distress and aversive emotions associated with such imagery The urge to engage in compulsions/to neutralise the imagery.

    Time frame: From the start of treatment until the end of treatment at 12 weeks.

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Study locations

1 site
  • Centre for Anxiety Disorders and Trauma
    London, United Kingdom
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 22, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06944366
Lead sponsor
King's College London
Responsible party
Sponsor
First posted
Apr 25, 2025
Start date
Aug 30, 2024
Primary completion
Apr 30, 2026
Completion
Apr 30, 2026
Last update
Jun 22, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.

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