An interventional study of Antecolic gastrojejunostomy and Retrocolic gastrojejunostomy in Pancreatic Cancer Resectable and Pancreas Neoplasms, sponsored by University of Thessaly. Recruiting at 1 site in Greece. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2025-06-06.
Sponsored by University of Thessaly · Not applicable, Interventional, and Treatment
Aim: This randomized clinical study aims to compare occurrence of DGE in patients undergoing either antecolic or retrocolic gastrojejunostomy following pancreaticoduodenectomy.
Methods: Participants of this study will be patients undergoing pylorus preserving pancreaticoduodenectomy at the Surgical Department of the University Hospital of Larissa. Patients will be randomized to undergo either an antecolic or a retrocolic gastrojejunostomy and the occurrence of DGE will then be compared between the two groups. Individuals younger than 18 or older than 75 years old, as well as patients who do not consent to participate in this trial, will be excluded.
Expected results: Based on available literature, antecolic gastrojejunostomy may be related with a lower incidence of DGE, without a statistically significant difference between the two methods. We aim to show if one of the two methods of gastrointestinal reconstruction (antecolic versus retrocolic) affects DGE.
3,235 studies on the registry are indexed under Pancreatic Neoplasms; 899 are open to participants now.
This study's planned enrollment of 76 is above the median of 46 across 2,424 interventional studies indexed under Pancreatic Neoplasms.
Browse Pancreatic Neoplasms studies →University of Thessaly is the lead sponsor of 188 studies on the registry; 44 are open to participants now.
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Exclusion Criteria:
Procedure: Antecolic gastrojejunostomy
Procedure: Retrocolic gastrojejunostomy
Gastrojejunostomy in front of the transverse colon
Gastrojejunostomy through the transverse mesocolon
Delayed Gastric Emptying
The occurence of delayed gastric emptying will be compared between two groups of patients: those who undergo an antecolic gastrojejunostomy and those who undergo a retrocolic approach.
Time frame: 3 years
Plan to share: Undecided
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University of Thessaly