ClinicalTrials.gg
CompletedNCT06878391Updated Oct 28, 2026

ISB With SSNB & ANB

An interventional study of Preemptive ultrasound-guided interscalene brachial plexus block and suprascapular nerve block and axillary nerve block in Rotator Cuff Tear, sponsored by Chuncheon Sacred Heart Hospital. Completed at 1 site in South Korea. Open to participants aged 20 Years and older. Per ClinicalTrials.gov, last updated 2026-10-28.

Sponsored by Chuncheon Sacred Heart Hospital · Not applicable, Interventional, and Supportive care

Updated Oct 28, 2026Now CompletedFirst site in South Korea+6 moreGo to Updates ↓

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Phase
Not applicable
Study type
Interventional
Enrollment
48
Allocation
Randomized
Ages
20 Years and older
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-13

Among 30 studies in Rotator Cuff Injuries with a site in Korea, Republic of — 3 open to participants now, 4 under way, 1 of them phase 3. Rotator Cuff Injuries · Korea, Republic of.

Enrollment
19th of 25
48 · median 74
Started
2025
with 1 other
No phase
17 of 30
1 open now
Registered
25th of 30
by date
Lead sponsor
5 of 30
Chuncheon Sacred Heart Hospital

Among the 30 studies in Rotator Cuff Injuries with a site in Korea, Republic of, this one is the 19th largest by enrollment of the 25 interventional ones that give a count, is one of 2 that started in 2025, is one of 17 with no phase, and was the 25th registered.

Rotator Cuff Injuries

631 studies on the registry are indexed under Rotator Cuff Injuries; 156 are open to participants now.

Browse Rotator Cuff Injuries studies →

Open to participants now

3 of the 30 studies in Rotator Cuff Injuries with a site in Korea, Republic of are open now. Recruiting first, the newest first:

All 3 open studies →

A study can be open while its sites in Korea, Republic of have not opened yet or have stopped. Only those recruiting at a site in Korea, Republic of →

Who these studies take

Of the 100 Rotator Cuff Injuries studies recruiting now, 40 (40%) set no upper age limit and 41 (41%) stop at 75 or younger; 9 take children under 18; 10 take healthy volunteers.

This study: 20 Years and older · all sexes · no healthy volunteers.

The full table on the hub →

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Watch this landscapeDownload CSVNarrow it in search →With an account: a weekly mail of what changed among 30 studies in Rotator Cuff Injuries with a site in Korea, Republic of, or all of them as a file.
02

Study summary

This study is a prospective, randomized, double-blind trial comparing patients who underwent arthroscopic rotator cuff repair and received an interscalene brachial plexus block (9 ml of 0.75% ropivacaine, 3 ml for each trunk) combined with suprascapular nerve block and axillary nerve block (each with 10 ml of 0.75% ropivacaine) versus those who received an interscalene brachial plexus block (9 ml of 0.75% ropivacaine, 3 ml for each trunk) combined with placebo suprascapular and axillary nerve blocks (each with 10 ml of 0.9% saline).

The study will compare subjective pain scores (VAS score) and patient satisfaction preoperatively and at 1, 3, 6, 12, 18, 24, 36, and 48 hours postoperatively. Additionally, 5 ml of venous blood will be collected preoperatively and at 1, 6, 12, 24, and 48 hours postoperatively to analyze and compare serum levels of cortisol, IL-6, IL-8, IL-1β, substance P, serotonin, β-endorphin, and norepinephrine.

03

Conditions studied

  • Rotator Cuff Tear

Browse trials for

04

Who can participate

Ages eligible
20 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • a definite rotator cuff tear that needed repair seen on preoperative magnetic resonancce imaging (MRI)
  • acceptance of arthroscopic surgery including rotator cuff repair
  • age same as or more than 20 years
  • acceptance of preemptive regional block and PCA, and blood testing

Exclusion criteria

Exclusion Criteria:

  • did not undergo arthroscopic rotator cuff repair
  • stopped PCA before 48 hours postoperatively because of associated side effects
  • a history of previous ipsilateral shoulder operation or fracture
  • a concomitant neurologic disorder around the shoulder
  • a failure of blood sampling including hemolysis, etc.
05

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Quadruple (Participant, Care provider, Investigator, Outcomes assessor)
Enrollment
48 participants (actual)

Study arms

  • Experimental
    ISB with SSNB & ANB

    An ultrasound-guided interscalene brachial plexus block (9 ml of 0.75% ropivacaine, 3 ml for each trunk) is performed immediately before arthroscopic rotator cuff repair , along with suprascapular nerve block and axillary nerve block (each with 10 ml of 0.75% ropivacaine). Patient Controlled Analgesia (PCA) at a low fixed dose: fentanyl-loading dose: 0.4㎍/kg, continuous dose: 0.2㎍/kg/h, nefopam-loading dose: 0.04mg/kg, continuous dose: 0.02mg/kg/h

    Procedure: Preemptive ultrasound-guided interscalene brachial plexus block and suprascapular nerve block and axillary nerve block

  • Placebo comparator
    ISB with placebo SSNB & ANB

    An ultrasound-guided interscalene brachial plexus block (9 ml of 0.75% ropivacaine, 3 ml for each trunk) is performed immediately before arthroscopic rotator cuff repair , along with suprascapular nerve block and axillary nerve block (each with 10 ml of saline). Patient Controlled Analgesia (PCA) at a low fixed dose: fentanyl-loading dose: 0.4㎍/kg, continuous dose: 0.2㎍/kg/h, nefopam-loading dose: 0.04mg/kg, continuous dose: 0.02mg/kg/h

    Procedure: Preemptive ultrasound-guided interscalene brachial plexus block and suprascapular nerve block and axillary nerve block

Interventions

  • ProcedurePreemptive ultrasound-guided interscalene brachial plexus block and suprascapular nerve block and axillary nerve block

    Preemptive ultrasound-guided interscalene brachial plexus block using ropivacaine, and suprascapular nerve block and axillary nerve block using ropivacaine or saline. Low fixed dose patient controlled analgesia (PCA) were done in the two group.

    Also known as: a low fixed dose patient controlled analgesia (PCA)

06

What researchers measure

Primary outcomes

  1. visual analog pain scale (VAS)

    0-10, 0: no pain, 10: very severe pain

    Time frame: preoperative, postoperative 1, 3, 6, 12, 18, 24, 36, 48 hour(s)

Secondary outcomes

  1. Patient's satisfaction (SAT)

    0-10, 0: not satisfied, 10: very much satisfied

    Time frame: preoperative, postoperative 1, 3, 6, 12, 18, 24, 36, 48 hour(s)

  2. IL-6

    pg/mL

    Time frame: preoperative, postoperative 1, 6, 12, 24, 48 hour(s)

  3. IL-8

    pg/mL

    Time frame: preoperative, postoperative 1, 6, 12, 24, 48 hour(s)

  4. IL-1β

    pg/mL

    Time frame: preoperative, postoperative 1, 6, 12, 24, 48 hour(s)

  5. Substance P

    pg/mL

    Time frame: preoperative, postoperative 1, 6, 12, 24, 48 hour(s)

  6. Serotonin

    ng/mL

    Time frame: preoperative, postoperative 1, 6, 12, 24, 48 hour(s)

  7. β -endorphin

    pg/mL

    Time frame: preoperative, postoperative 1, 6, 12, 24, 48 hour(s)

07

Study locations

1 site
  • Hallym University Chuncheon Sacred Heart Hospital
    Chuncheon, Gangwon-do 24253, South Korea
08

References and documents

Publications

  • Lee JJ, Kim DY, Hwang JT, Lee SS, Hwang SM, Kim GH, Jo YG. Effect of ultrasonographically guided axillary nerve block combined with suprascapular nerve block in arthroscopic rotator cuff repair: a randomized controlled trial. Arthroscopy. 2014 Aug;30(8):906-14. doi: 10.1016/j.arthro.2014.03.014. Epub 2014 May 29. PubMed 24880194 ↗
  • Lee JJ, Kim DY, Hwang JT, Song DK, Lee HN, Jang JS, Lee SS, Hwang SM, Moon SH, Shim JH. Dexmedetomidine combined with suprascapular nerve block and axillary nerve block has a synergistic effect on relieving postoperative pain after arthroscopic rotator cuff repair. Knee Surg Sports Traumatol Arthrosc. 2021 Dec;29(12):4022-4031. doi: 10.1007/s00167-020-06288-8. Epub 2020 Sep 25. PubMed 32975624 ↗

Individual participant data

Plan to share: No — We can decide it after the termination of this study.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedDate before it movedWhere the date was before it movedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Mar 2025 to primary completion in Mar 2026, 11 months.

Of 228 non-industry interventional studies with no phase under Rotator Cuff Injuries, half reached primary completion within 19 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 39. This study's 11 months is below that.

Counting every sponsor, half of 252 studies reached it within 23 months; a quarter within 11 and three quarters within 44.

Since we started tracking on Sep 25, 2026, the dates moved once, on Oct 28, 2026: primary completion Jan 2027 → Mar 2026 and completion Jan 2027 → Sep 2026.

Earlier changes are on the record history on ClinicalTrials.gov ↗

How these figures are worked out, and which studies are left out of them.

Registered
Mar 13, 2025
First posted
Mar 17, 2025
StartActual
Mar 24, 2025
Primary completionActual
Mar 21, 2026was Jan 2027
CompletionActual
Sep 21, 2026was Jan 2027
Last update
Oct 28, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Status
Recruiting→Completed
changed Oct 28, 2026
Sites
1 site added, 2 sites removed — first site in South Korea; no longer in Korea, Republic of
Show site
  • Hallym University Chuncheon Sacred Heart Hospital · Chuncheon, South Korea
Show 2 removed
  • Hallym University Chuncheon Sacred Heart Hospital · Chuncheon, Korea, Republic of
  • Hallym University Chuncheon Sacred Heart Hospital · Chuncheon, Korea, Republic of
Oct 28, 2026
Primary completion
Jan 31, 2027→Mar 21, 2026 (actual)
Oct 28, 2026
Study completion
Jan 31, 2027→Sep 21, 2026 (actual)
Oct 28, 2026
Enrollment
100 (estimated)→48 (actual)
Oct 28, 2026
Secondary outcomes
2 removed
What changed in the outcomes
  • Removedplasma CortisolTime frame: preoperative, postoperative 1, 6, 12, 24, 48 hour(s)
  • RemovednorepinephrineTime frame: preoperative, postoperative 1, 6, 12, 24, 48 hour(s)
Oct 28, 2026
Show all 1 update
  1. Oct 28, 2026
    Recruiting→Completed
    1 site added, 2 sites removed — first site in South Korea; no longer in Korea, Republic of
    Show site
    • Hallym University Chuncheon Sacred Heart Hospital · Chuncheon, South Korea
    Show 2 removed
    • Hallym University Chuncheon Sacred Heart Hospital · Chuncheon, Korea, Republic of
    • Hallym University Chuncheon Sacred Heart Hospital · Chuncheon, Korea, Republic of
    Primary completion Jan 31, 2027→Mar 21, 2026 (now actual)
    Study completion Jan 31, 2027→Sep 21, 2026 (now actual)
    Enrollment 100 (estimated)→48 (actual)
    Secondary outcomes 2 removed
    What changed in the outcomes
    • Removedplasma CortisolTime frame: preoperative, postoperative 1, 6, 12, 24, 48 hour(s)
    • RemovednorepinephrineTime frame: preoperative, postoperative 1, 6, 12, 24, 48 hour(s)
    + 5 other changes: index terms, verification date, oversight details, contact details and references

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT06878391
Lead sponsor
Chuncheon Sacred Heart Hospital
Responsible party
Jung-Taek Hwang (Professor, Chuncheon Sacred Heart Hospital) — Principal investigator
First posted
Mar 17, 2025
Start date
Mar 24, 2025
Primary completion
Mar 21, 2026
Completion
Sep 21, 2026
Last update
Oct 28, 2026

Study contacts

Jung-Taek Hwang, MD, PhD
principal investigator · Hallym University Medical Center

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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