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CompletedNCT06873295GERBILLEUpdated Mar 12, 2025

Management Strategy for Acute Cholecystitis in the Digestive Surgery Department and Geriatric Unit in Subjects Over and Under 75 Years

An observational study in Acute Cholecystitis, sponsored by Centre Hospitalier Universitaire de Nīmes. Completed at 1 site in France. Open to participants aged 19 Years and older. Per ClinicalTrials.gov, last updated 2025-03-12.

Sponsored by Centre Hospitalier Universitaire de Nīmes · Observational

Study type
Observational
Model
Other
Time perspective
Retrospective
Enrollment
424
Ages
19 Years and older
Sex
All
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Study summary

The management of these often frail elderly patients, with more comorbidities and declining functional capacities, is more complex and justifies a specific, tailored approach.

Age is also associated with an increasing prevalence of gallstones. The disadvantages of "cold" surgery (longer hospital stay, higher cost, risk of disease recurrence in the interim, difficult surgery with more scar tissue due to repeated inflammation) have to be weighed against the high operative risk in the case of emergency surgery, leading to strict criteria for early cholecystectomy.

These criteria are rarely met in geriatric patients, who thus enter a hospital cycle whose impact on morbidity and mortality, as well as on loss of autonomy, has been demonstrated in this population. What's more, the deteriorating general condition of frail elderly patients means that a number of them end up being definitively rejected for surgery, despite an initial strategy of cold cholecystectomy.

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Conditions studied

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In context

Cholecystitis

266 studies on the registry are indexed under Cholecystitis; 46 are open to participants now.

This study's enrollment of 424 is above the median of 200 across 90 observational studies indexed under Cholecystitis.

Browse Cholecystitis studies →

Lead sponsor

Centre Hospitalier Universitaire de Nīmes is the lead sponsor of 587 studies on the registry; 96 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
19 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients hospitalized in the digestive surgery department and geriatric perioperative unit of the CHU de Nîmes with a diagnosis of acute cholecystitis.

Inclusion criteria

  • Patients over 18 years of age.
  • Diagnosis of acute cholecystitis.
  • Hospitalization in the digestive surgery department and geriatric perioperative unit of Nîmes University Hospital.

Exclusion criteria

Exclusion Criteria:

  • Patients under 18 years of age.
  • Opposition of the patient to his inclusion in the study after sending the letter of information and non-opposition.
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Study design

Observational model
Other
Time perspective
Retrospective
Enrollment
424 participants (actual)
Patient registry
No
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What researchers measure

Primary outcomes

  1. Rate of patients with an initial cold cholecystectomy strategy who did not undergo surgery, died or underwent emergency surgery

    Percentage

    Time frame: Up to 6 months, from date of first collection to date of end of collection

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Study locations

1 site
  • Simonet Anne Clarisse
    Nîmes, France
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 12, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06873295
Lead sponsor
Centre Hospitalier Universitaire de Nīmes
Responsible party
Sponsor
First posted
Mar 12, 2025
Start date
Mar 22, 2023
Primary completion
Oct 22, 2023
Completion
Oct 22, 2024
Last update
Mar 12, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2025. You cannot join it, but the record below documents what was studied.

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