An interventional study of Serratus posterior superior intercostal plane block and Thoracic Paravertebral Block in Mastectomy, Peripheral Nerve Block and Pain Management, sponsored by Ankara Etlik City Hospital. Completed at 1 site in Turkey (Türkiye). Open to female participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2026-02-24.
Sponsored by Ankara Etlik City Hospital · Not applicable, Interventional, and Treatment
Breast cancer is the most common malignancy in women, and surgery is one of the cornerstone treatments for breast cancer. Postoperative pain can significantly reduce patients' quality of life and acute pain may even trigger chronic pain syndrome.
Nerve blocks reduces opioid consumption in the postoperative period by providing better pain control and therefore has advantages such as fewer side effects and less risk of pulmonary and cardiac complications.
In this study; it was aimed to compare the analgesic effectiveness of serratus posterior superior intercostal plane block and thoracic paravertebral block in the postoperative period in patients who underwent mastectomy.
1,190 studies on the registry are indexed under Agnosia; 508 are open to participants now.
This study's enrollment of 60 is below the median of 78 across 1,024 interventional studies indexed under Agnosia.
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Exclusion Criteria:
After the patients are monitored and in the supine position, after appropriate field sterilization, a serratus posterior superior intercostal plane block will be performed on the patients using 30 ml of local anesthetic solution (0.25% bupivacain) under ultrasound guidance. In the intraoperative period, intravenous analgesics (dexketoprofen 50 mg, tramadol 100 mg) will be given.
Procedure: Serratus posterior superior intercostal plane block
After the patients are monitored and in the supine position, after appropriate field sterilization, a thoracic paravertebral block will be performed on the patients using 30 ml of local anesthetic solution (0.25% bupivacain) under ultrasound guidance. In the intraoperative period, intravenous analgesics (dexketoprofen 50 mg, tramadol 100 mg) will be given.
Procedure: Thoracic Paravertebral Block
Serratus posterior superior intercostal plane block will be performed on the patients using 30 ml of 0.25% bupivacaine under ultrasound guidance. Additionally, in the postoperative period a paracetamol dose of 1 g every 8 hours and a dexketoprofen dose of 50 mg twice daily were administered iv for multimodal analgesia.
Thoracic paravertebral block will be performed on the patients using 30 ml of 0.25% bupivacaine under ultrasound guidance. Additionally, in the postoperative period a paracetamol dose of 1 g every 8 hours and a dexketoprofen dose of 50 mg twice daily were administered iv for multimodal analgesia.
Pain Scores
Pain will be assessed at rest and while coughing using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain). Pain assessment will be done at 0st, 1st, 2nd,4th, 12th, and 24th hours after surgery.
Time frame: On the operation day
Intraoperative opioid consumption
Remifentanil consumption for intraoperative period will be recorded
Time frame: Intraoperative period
Postoperative Tramadol Consumption
Tramadol consumption for 24 hours will be recorded
Time frame: On the operation day
This study is completed, as verified in Feb 2026. You cannot join it, but the record below documents what was studied.
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Ankara Etlik City Hospital