An interventional study of I-PRF and Control in Alveolar Osteitis, Pain and Dry Socket, sponsored by Eskisehir Osmangazi University. Completed at 1 site in Turkey. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-02-19.
Sponsored by Eskisehir Osmangazi University · Not applicable, Interventional, and Other
Literature review showed that there are no studies on the use of i-PRF in alveolitis cases. The aim of this study was to investigate the effect of i-PRF on the treatment of alveolitis. The hypothesis of the study was that i-PRF applied to alveolitis patients would reduce pain.
The present study will include 60 healthy patients over 18 years of age with alveolitis. 60 patients will be randomly divided into two groups: Control and I-PRF. After irrigation of the sockets, no substance will be applied to the control group, and I-PRF will be applied to the study group. Postoperative pain will be measured on the 3rd and 7th days.
46 studies on the registry are indexed under Dry Socket; 10 are open to participants now.
This study's enrollment of 60 is close to the median of 60 across 41 interventional studies indexed under Dry Socket.
Browse Dry Socket studies →Eskisehir Osmangazi University is the lead sponsor of 153 studies on the registry; 27 are open to participants now.
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Healthy individuals without systemic disease Patients with complete data and attending their appointments
Exclusion Criteria:
Patients who smoke Pregnant or breastfeeding female patients with bleeding disorders and diabetics Patients currently or previously using bisphosphonates or receiving radiotherapy to the jaw Patients unable to consent to participate in the study
I-PRF Application
Device: I-PRF
standard treatment
Other: Control
After local anesthesia is injected, alveolar curettage is performed and the socket is irrigated with saline solution. I-PRF is given to patients in the experimental group.
After local anesthesia is injected, alveolar curettage is performed and the socket is irrigated with saline solution.
Change in post-operative pain assessed: visual analog (VAS) scale
VAS measured on a 10cm scale, where 0 represents no pain and 10 represents maximum pain
Time frame: postoperative 3rd, and 7th days
Plan to share: No — IPD may share with other researchers upon request
This study is completed, as verified in Feb 2025. You cannot join it, but the record below documents what was studied.
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