CClinicalTrials.gg
Not yet recruitingNCT06749353Updated Jan 9, 2025

Virtual Reality to Reduce Intraoperative Anxiety in Vasectomies Under Local Anesthesia

An interventional study of Virtual reality in Anxiety, sponsored by Hospital Mutua de Terrassa. Not yet recruiting at 1 site in Spain. Open to male participants aged 20 Years to 90 Years. Per ClinicalTrials.gov, last updated 2025-01-09.

Sponsored by Hospital Mutua de Terrassa · Not applicable, Interventional, and Supportive care

Phase
Not applicable
Study type
Interventional
Enrollment
148
Allocation
Randomized
Ages
20 Years to 90 Years
Sex
Male
01

Study summary

Vasectomy is an elective and ambulatory surgery, typically performed under local anaesthesia. The most common problem that we have found among patients is the anxiety and the apprehension to face the procedure.

Virtual reality (VR), as a novel tool, is relatively underutilized in such medical context. It has been successfully employed across various medical domains, aiding in the training of surgeons, enhancing procedural planning, and offering psychological support to patients.

This project aims to assess the effectiveness of employing distraction maneuverers, using virtual reality glasses, during the intraoperative period on vasectomy surgery, to mitigate anxiety during the surgical process.

We want to develop a randomized clinical trial, single-centre study with a control group (conventional procedure) and an intervention group (Virtual reality Glasses). Anxiety was measured using cortisol level through a biomarker saliva test, involving pre and post-procedure samples for each patient. Additionally, we used the State-Trait Anxiety Inventory (STAI) pre and post procedure to evaluate the anxiety and the correlation with the cortisol levels, To evaluate the patient's satisfaction with the used of VR glasses a satisfaction survey was developed. The study protocol has received approval from the ethical committee of our institution.

The investigators expect to find statistically significant differences in salivary cortisol levels on postoperative samples to prove that VR helps to have a better experience and reduce the intraoperative anxiety.

Read the detailed description

Upon arrival at the ambulatory surgery unit (ASU) for a vasectomy, the patient will be informed about the study. If they agree to participate, they will be given an informed consent form to read and sign.

At the ASU, the nurse will record the patient's age and provide the STAI Trait-State scale for completion before entering the operating room. A preoperative saliva sample will be collected to analyze cortisol levels. The patient will be entered into the database and randomized into either the control or intervention group.

Once in the operating room, the patient will be positioned, and a preoperative verification will be performed. The urologist will speak with the patient to provide information, explain the surgery, and confirm the procedure. Heart rate and blood pressure will be recorded. For patients in the intervention group, virtual reality glasses with the "Lending Moments" program will be applied. This program simulates a sunset on a paradisiacal beach while a calming voice guides the patient through relaxation and meditation techniques. The surgical procedure will be performed during this time. Heart rate and blood pressure will be recorded again during the procedure.

Upon completion of the surgery, the patient will be informed and the virtual reality glasses will be removed for patients in the intervention group. The patient will be accompanied to the waiting room, where a postoperative saliva sample will be collected. The patient will be given the STAI State scale and a questionnaire to assess their experience. Heart rate and blood pressure will be recorded postoperatively.

Samples will be sent to the laboratory for processing the same day. Descriptive statistics will be computed, including means (with standard deviations), frequencies, and proportions, according to the variable type at each phase. The Kolmogorov-Smirnov test will be used to assess the normality of quantitative variables. For variables that do not follow a normal distribution, medians (and the 25th and 75th percentiles) will be reported.

For bivariate analysis, Student's t-test or the Mann-Whitney U test will be used for quantitative variables, and the chi-squared test will be used for categorical variables.

02

Conditions studied

  • Anxiety

Browse trials for

Keywords

  • anxiety
  • biomarkers
  • cortisol
  • vasectomy
  • virtual reality
03

Who can participate

Ages eligible
20 Years to 90 Years
Sexes eligible
Male
Accepts healthy volunteers
No

Inclusion criteria

  • Male
  • Age between 20 and 90 years old
  • Intervention between 8 am to 12 am.
  • Vasectomy under local anesthesia

Exclusion criteria

Exclusion Criteria:

  • Language barrier
  • Oncological urological syurgery
  • Surgery time superior to 30 minuts
  • Intellectual disability
  • STAI Trait > 70%
  • Intervention after 12 am
04

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
148 participants (estimated)

Study arms

  • No intervention
    USUAL

    In the control group, we will perform the surgical procedure as usual, without any distraction maneuvers, under local anesthesia.

  • Experimental
    VIRTUAL REALITY

    In the study group, we will perform the vasectomy under local anesthesia and provide patients with virtual reality glasses as a distraction technique, aiming to reduce intraoperative anxiety.

    Device: Virtual reality

Interventions

  • DeviceVirtual reality

    We will use a virtual reality glasses with the 'Lending Moments' program, where patients can experience a sunset on a paradise beach while listening to a soothing voice that guides them through the experience with relaxation and meditation techniques. During this time, we will proceed with the surgical intervention.

05

What researchers measure

Primary outcomes

  1. Biomarker

    Cortisol is a commun stress biomarker used in many studies.

    Time frame: 96 weeks

  2. Psicological Scale

    We will mesure the intraoperative anxiety

    Time frame: 96 weeks

Secondary outcomes

  1. Patient experience

    The patient will complete a questionnaire regardind the attention recieved and subjective anxiety percieved. It has 9 questions, where the patient could evaluate the experience lived during the surgery from 1, being a very bad experience, to 10 being better experience possible.

    Time frame: 96 weeks

  2. Blood preasure

    Time frame: 96 weeks

  3. Heart rate

    Time frame: 96 weeks

06

Study locations

1 site
  • Hospital Univesitari Mútua de Terrassa
    Terrassa, Barcelona 08221, Spain
    • Pilar Arcusa · Contact · parcusa@mutuaterrassa.es · +34 937365050
    • Maria Claret, RN, MsC · Contact
    • Carles Castillo, Physician · Contact
    • Alba Gomariz, Physician · Contact
    • Josep M Gili, Physician · Contact
    • Josep M Caballero, PhD · Contact
    • Juan Camilo Pereira, Physician · Contact
    • Ignasi Gallardo, Physician · Contact
07

References and documents

Publications

  • (1) Mallari B, Spaeth EK, Goh HX, Slijepcevic N, Guo Y, Doherty CJ, Yeomans DC, Burns LC. Virtual Reality Distraction for Pain Control During Medical Procedures: A Systematic Review of Randomized Controlled Trials. Clin J Pain. 2019

Individual participant data

Plan to share: No

08

Registry details

Key details

Study ID
NCT06749353
Lead sponsor
Hospital Mutua de Terrassa
Responsible party
Sponsor
First posted
Dec 27, 2024
Start date
Jan 2025 (estimated)
Primary completion
Dec 2025 (estimated)
Completion
Dec 2026 (estimated)
Last update
Jan 9, 2025

Study contacts

Maria Claret, Nurse
Contact
mariaclaretgutierrez@gmail.com
+34 699259588
Carles Castillo, Urological Doctor
Contact
carlescastillo@mutuaterrassa.cat
+34649646220 ext. 61727
Olga Monistrol, RN, MsC, PhD
principal investigator

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Jan 2025. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion