An observational study in Ventricular Tachycardia (VT) and Ventricular Fibrillation, sponsored by Medtronic Cardiac Rhythm and Heart Failure. Active, not recruiting at 2 sites in China. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-15.
Sponsored by Medtronic Cardiac Rhythm and Heart Failure (part of Medtronic) · Observational
The goal of this observational study is to investigate the changes of LBB EGM during daily activities and overdrive pacing at the time of peri-implantation and up to 6-month follow-ups of ICD/CRT-D patients. The main question it aims to answer is:
451 studies on the registry are indexed under Tachycardia, Ventricular; 120 are open to participants now.
This study's enrollment of 50 is below the median of 167 across 147 observational studies indexed under Tachycardia, Ventricular.
Browse Tachycardia, Ventricular studies →Medtronic Cardiac Rhythm and Heart Failure is the lead sponsor of 240 studies on the registry; 4 are open to participants now.
Of its 19 completed or terminated interventional studies of FDA-regulated products, 18 (95%) have results posted.
Counted across the registry records on this site, refreshed daily.
The study selected two study site in China. One is a Tertiary A hospital in Zhejiang Province, and another is a hospital in Shanghai. Both of the two sites locate in south east of China. This study will enroll around 50 subjects who meet the inclusion and exclusion criteria from the ICD or CRT-D patients who have received LBBAP in the two hospitals.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Patients' EGMs can be recorded by Holter DR220
R-wave amplitude of LBB EGM
Amplitude in millivolt
Time frame: At the enrollment, 3 months after enrollment and 6 months after enrollment
EGM morphology-LVAT
LVAT in millisecond, calculated based on electrogram recorded by LBB lead
Time frame: At the enrollment, 3 months after enrollment and 6 months after enrollment
echocardiography results-LVEF
LVEF in percentage
Time frame: At the enrollment and 6 months after enrollment
echocardiography results-SV
SV in millilitre
Time frame: At the enrollment and 6 months after enrollment
echocardiography results-LVEDV
LVEDV in millilitre
Time frame: At the enrollment and 6 months after enrollment
echocardiography results-LVESV
LVESV in millilitre
Time frame: At the enrollment and 6 months after enrollment
echocardiography results-LVEDD
LVEDD in millimetre
Time frame: At the enrollment and 6 months after enrollment
echocardiography results-LVESD
LVESD in millimetre
Time frame: At the enrollment and 6 months after enrollment
Plan to share: No
Ran from Feb 2025 to primary completion in Aug 2026, 17 months.
Of 69 observational studies under Tachycardia, Ventricular, half reached primary completion within 46 months of starting (the median), counting those still running; a quarter within 28 and three quarters within 108. This study's 17 months is below that.
Since we started tracking on Sep 25, 2026, the dates moved once, on Oct 15, 2026: primary completion Jul 2026 → Aug 2026 and completion Jul 2026 → Oct 2026.
Earlier changes are on the record history on ClinicalTrials.gov ↗
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is active, not recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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Medtronic Cardiac Rhythm and Heart Failure →