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RecruitingNCT06702761DEPRESS/PHQ-9Updated Mar 4, 2026

Prevalence and Severity of Depression Among Cardiothoracic Surgery Healthcare Workers in Baghdad: A PHQ-9 Cross-Sectional Study

An observational study in Depression Disorders, sponsored by Al-Nahrain University. Recruiting at 1 site in Iraq. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-03-04.

Sponsored by Al-Nahrain University · Observational

From the registry’s dates

  • Started Dec 2024; still recruiting 1 year 10 months later.
Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
200
Ages
18 Years and older
Sex
All
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Study summary

This observational study aims to estimate the prevalence and severity of depression in HCWs in cardiothoracic surgery departments in Baghdad City, Iraq, using a self-administered PHQ-9 questionnaire. The main questions it aims to answer are:

What is the prevalence of depression among cardiothoracic surgery healthcare workers? How is the severity of depression distributed within this group? Are there specific occupational or demographic factors associated with higher levels of depression?

Participants will:

Fill out the PHQ-9 in order to measure the severity of depressive symptoms at a specific moment in time.

Demographic and occupational details such as age, gender, years of experience and position held should be taken to look for possible relationship with depression.

Read the detailed description

Major depressive disorder is a prevalent, severe, and recurring mental health condition.There is a significant difference in the prevalence of major depressive disorder across various socioeconomic contexts and countries. Depression is a debilitating mental illness, severely impacting psychosocial function and quality of life.

Individuals, including healthcare workers, are at risk of developing various psychological disorders, with depression being the most prevalent. In Iraq, healthcare workers are particularly vulnerable to psychological distress due to the nature of their job. They often have to deal with heavy workloads, night shifts, and shift work, which can take a toll on their mental well-being. These occupational stress factors can lead to burnout, anxiety, sleep problems, psychiatric disorders, or even depression. It has been reported that the screening for depression among healthcare workers is on the rise. Healthcare workers and individuals who work in the healthcare industry often experience symptoms of anxiety and depression at a significant rate.

There are several tools that can be used to screen for depressive disorders. One commonly used instrument in primary care is the Patient Health Questionnaire-9 (PHQ-9), which is a brief, self-administered, and easy-to-score tool that is well-validated for detecting and monitoring changes in depression severity. and detection of this condition in large epidemiological studies As this instrument is based on DSM-IV criteria, it tends to identify cases with Major Depressive Episode (MDE) when the scores are high. Additionally, it can be utilized to evaluate the intensity of depression by distinguishing between mild to severe cases. However, it is important to note that there is mounting evidence that the cut-off points used to determine the degree of severity may differ based on various contexts.

This study addresses the mental health gap among Iraqi healthcare workers, particularly in cardiothoracic surgery, within a healthcare system strained by war, resource shortages, and heavy patient loads. Despite these challenges, few studies assess depression in this group. Findings aim to inform mental health support policies for high-stress medical fields in Iraq.

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Conditions studied

  • Depression Disorders

Keywords

  • PHQ-9
  • HCWs
03

In context

Lead sponsor

Al-Nahrain University is the lead sponsor of 26 studies on the registry; 20 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

The study targets cardiothoracic surgical departments' health care workers in Baghdad's hospitals. This encompasses cardiothoracic surgeons, anesthetists, nurses, perfusionists, and many related personnel who mostly come into direct contact with the patients. These persons work in conditions that may trigger mental health problems, such as extended working hours, intricate processes, and acute status of patients. The participants are chosen to be at least 18 years old, with different years of experience, and diagnosed to determine the rate of depression in the mentioned specific medical line.

Inclusion criteria

  • Healthcare professionals actively working in cardiothoracic surgery departments in Baghdad, including surgeons, anesthesiologists, nurses, and support staff.
  • Participants who provide informed consent for participation in the study.
  • Able to complete questionnaire form.

Exclusion criteria

Exclusion Criteria:

  • Individuals with a previously diagnosed psychiatric condition other than depression that could confound the results.
  • Incomplete or missing responses on the PHQ-9 questionnaire.
  • Refusal to provide informed consent.
  • Participants are currently undergoing treatment for depression or other mental health conditions.
  • Healthcare workers on long-term leave or who have not actively worked in the cardiothoracic surgery department for the past 3 months.
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Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
200 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Prevalence of Depression

    Proportion of cardiothoracic surgery HCWs at Al-Kadhimiya Teaching Hospital who exhibit depressive symptoms.

    Time frame: Data collection will occur over a 3-months period, with each participant completing the assessment at a single point during this time frame.

  2. Severity of Depression

    The severity of depression in this study will be determined based on the scores obtained from the Patient Health Questionnaire-9 (PHQ-9). The PHQ-9 categorizes depression severity as follows: Minimal depression: Scores 0-4, indicating little to no symptoms. Mild depression: Scores 5-9, suggesting occasional symptoms that may not significantly affect daily functioning. Moderate depression: Scores 10-14, indicating more frequent symptoms that can interfere with daily life. Moderately severe depression: Scores 15-19, showing pronounced symptoms that significantly impact daily activities. Severe depression: Scores 20-27, with symptoms that are debilitating.

    Time frame: Data collection will occur over a 3-months period, with each participant completing the PHQ-9 assessment at a single point during this time frame.

  3. Patient Health Questionnaire-9 (PHQ-9)

    The total score can range from 0 to 27. Higher scores indicate greater severity of depression.

    Time frame: Data collection will occur over a 3-months period, with each participant completing the PHQ-9 assessment at a single point during this time frame.

07

Study locations

1 of 1 sites recruiting
  • College of Medicine - Al-Nahrain University
    Baghdad, Iraq
    • Luma K Mohammed, MBChB,FIBMS/CM · Contact · lumakmohammed@nahrainuniv.edu.iq · +964770225676
    • Abdul-Ilah R. Khamis · Principal investigator
    • Eman Gomaa Allam, Intern doctor · Sub investigator
    • Saja Jaafar Abotaleb, M.B.CH.B · Sub investigator
    • Othman M. Mutar, Student · Sub investigator
    • Zaid Salwan Akram, Student · Sub investigator
    • Baraa AL-Obaidi M.B.CH.B · Sub investigator
    Recruiting
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References and documents

Publications

  • Kendrick T, Dowrick C, McBride A, Howe A, Clarke P, Maisey S, Moore M, Smith PW. Management of depression in UK general practice in relation to scores on depression severity questionnaires: analysis of medical record data. BMJ. 2009 Mar 19;338:b750. doi: 10.1136/bmj.b750. PubMed 19299475 ↗
  • Zimmerman M, Martinez JH, Friedman M, Boerescu DA, Attiullah N, Toba C. Speaking a more consistent language when discussing severe depression: a calibration study of 3 self-report measures of depressive symptoms. J Clin Psychiatry. 2014 Feb;75(2):141-6. doi: 10.4088/JCP.13m08458. PubMed 24345406 ↗
  • Haddad M, Walters P, Phillips R, Tsakok J, Williams P, Mann A, Tylee A. Detecting depression in patients with coronary heart disease: a diagnostic evaluation of the PHQ-9 and HADS-D in primary care, findings from the UPBEAT-UK study. PLoS One. 2013 Oct 10;8(10):e78493. doi: 10.1371/journal.pone.0078493. eCollection 2013. PubMed 24130903 ↗
  • Tracy M, Morgenstern H, Zivin K, Aiello AE, Galea S. Traumatic event exposure and depression severity over time: results from a prospective cohort study in an urban area. Soc Psychiatry Psychiatr Epidemiol. 2014 Nov;49(11):1769-82. doi: 10.1007/s00127-014-0884-2. Epub 2014 May 10. PubMed 24816599 ↗
  • van Dooren FE, Denollet J, Verhey FR, Stehouwer CD, Sep SJ, Henry RM, Kremers SP, Dagnelie PC, Schaper NC, van der Kallen CJ, Koster A, Pouwer F, Schram MT. Psychological and personality factors in type 2 diabetes mellitus, presenting the rationale and exploratory results from The Maastricht Study, a population-based cohort study. BMC Psychiatry. 2016 Jan 27;16:17. doi: 10.1186/s12888-016-0722-z. PubMed 26817600 ↗
  • Michal M, Wiltink J, Lackner K, Wild PS, Zwiener I, Blettner M, Munzel T, Schulz A, Kirschner Y, Beutel ME. Association of hypertension with depression in the community: results from the Gutenberg Health Study. J Hypertens. 2013 May;31(5):893-9. doi: 10.1097/HJH.0b013e32835f5768. PubMed 23449018 ↗
  • Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001 Sep;16(9):606-13. doi: 10.1046/j.1525-1497.2001.016009606.x. PubMed 11556941 ↗
  • Kroenke K, Spitzer RL, Williams JB, Lowe B. The Patient Health Questionnaire Somatic, Anxiety, and Depressive Symptom Scales: a systematic review. Gen Hosp Psychiatry. 2010 Jul-Aug;32(4):345-59. doi: 10.1016/j.genhosppsych.2010.03.006. Epub 2010 May 7. PubMed 20633738 ↗
  • Moitra M, Rahman M, Collins PY, Gohar F, Weaver M, Kinuthia J, Rossler W, Petersen S, Unutzer J, Saxena S, Huang KY, Lai J, Kumar M. Mental Health Consequences for Healthcare Workers During the COVID-19 Pandemic: A Scoping Review to Draw Lessons for LMICs. Front Psychiatry. 2021 Jan 27;12:602614. doi: 10.3389/fpsyt.2021.602614. eCollection 2021. PubMed 33584383 ↗
  • Soltani S, Tabibzadeh A, Zakeri A, Zakeri AM, Latifi T, Shabani M, Pouremamali A, Erfani Y, Pakzad I, Malekifar P, Valizadeh R, Zandi M, Pakzad R. COVID-19 associated central nervous system manifestations, mental and neurological symptoms: a systematic review and meta-analysis. Rev Neurosci. 2021 Jan 13;32(3):351-361. doi: 10.1515/revneuro-2020-0108. Print 2021 Apr 27. PubMed 33618441 ↗
  • Kim K, Lee S, Choi YH. Relationship between occupational stress and depressive mood among interns and residents in a tertiary hospital, Seoul, Korea. Clin Exp Emerg Med. 2015 Jun 30;2(2):117-122. doi: 10.15441/ceem.15.002. eCollection 2015 Jun. PubMed 27752582 ↗
  • Hegney DG, Craigie M, Hemsworth D, Osseiran-Moisson R, Aoun S, Francis K, Drury V. Compassion satisfaction, compassion fatigue, anxiety, depression and stress in registered nurses in Australia: study 1 results. J Nurs Manag. 2014 May;22(4):506-18. doi: 10.1111/jonm.12160. Epub 2013 Nov 1. PubMed 24175955 ↗
  • Kessler RC, Bromet EJ. The epidemiology of depression across cultures. Annu Rev Public Health. 2013;34:119-38. doi: 10.1146/annurev-publhealth-031912-114409. PubMed 23514317 ↗
  • Trivedi MH. Major Depressive Disorder in Primary Care: Strategies for Identification. J Clin Psychiatry. 2020 Mar 17;81(2):UT17042BR1C. doi: 10.4088/JCP.UT17042BR1C. PubMed 32220155 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 4, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06702761
Lead sponsor
Al-Nahrain University
Responsible party
Abdulillah R. Khamees (Principal Investigator, Al-Nahrain University) — Principal investigator
First posted
Nov 25, 2024
Start date
Dec 1, 2024
Primary completion
Dec 1, 2026 (estimated)
Completion
Dec 15, 2026 (estimated)
Last update
Mar 4, 2026

Study contacts

Abdul-Ilah R. Khamis
Contact
allaabed987@ced.nahrainuniv.edu.iq
+9647838571013
Yaser aamer Eisa Alhaibi, Assistant professor
study director · College Of Medicine - Nahrain University

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

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