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CompletedNCT06700265Updated Apr 28, 2026

Ultrasound Airway Examination as a Tool for Detection of Difficult Intubation in Adult Patients

An observational study in Difficult Airway, sponsored by National Cancer Institute, Egypt. Completed at 1 site in Egypt. Open to participants aged 18 Years to 70 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-04-28.

Sponsored by National Cancer Institute, Egypt · Observational

Study type
Observational
Model
Other
Time perspective
Cross-sectional
Enrollment
246
Ages
18 Years to 70 Years
Sex
All
01

Study summary

the goal of the observational study to measure the effectiveness of neck ultrasound in prediction of difficult intubation in adult patients

Read the detailed description

All participant undergoing elective surgery under general anesthesia will go a detailed preoperative sonographic assessment by the anesthesiologist who has experience in airway ultrasound for measurement of Hyomental distance, thyrohyoid distance, thyroid cricoid, anterior soft tissue thickness at levels of hyoid bone, cricoid cartilage and vocal cord and all measurement will be measured in neutral and sniffing position.

after induction of general anesthesia intubation will done by macintosh laryngoscope and degree of difficulty of intubation will be measured by cormack-lehane classification without any external manipulation

02

Conditions studied

  • Difficult Airway

Keywords

  • airway ultrasound
03

In context

Lead sponsor

National Cancer Institute, Egypt is the lead sponsor of 133 studies on the registry; 29 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

all population undergoining surgical operation requiring general anesthesia and endotracheal intubation

Inclusion criteria

  • Adult patients above18 years old
  • Both sex
  • Requiring general anesthesia with endotracheal intubation

Exclusion criteria

Exclusion Criteria:

  • Emergency surgery,
  • patients with limited mouth, head or neck movement,
  • patients with temporomandibular joint impairment,
  • fracture or tumors of mandible,
  • patients requiring awake intubation,
  • uncooperative patients,
  • any cervical spine limitation movement
  • neck swelling or tumor
  • Prominent teeth deformities.
05

Study design

Observational model
Other
Time perspective
Cross-sectional
Enrollment
246 participants (actual)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. measurement of effectiveness of neck ultrasound use of ultrasound measurement in prediction of difficult intubation

    In cormack lehan classification of laryngoscopy view

    Time frame: 30 min after ultrasound measurements at time of induction of anesthesai

Secondary outcomes

  1. Hyomental distance in neutral position

    In centimetres

    Time frame: 30 min before operation

  2. Throhyoid distance in neutral position

    In centimetres

    Time frame: 30 min before operation

  3. Cricothyriod distance in neutral position

    In centimetres

    Time frame: 30 min before operation

  4. Anterior soft tissue thickness at level of hyoid bone in neutral position

    In centimetres

    Time frame: 30 min before opeqrtio

  5. Anterior soft tissue thickness at level of epiglottis in neutral position

    In centimetres

    Time frame: 30 min befor operation

  6. Anterior soft tissue thickness at level of vocal cord in neutral position

    In centimetres

    Time frame: 30 min before operation

  7. Hyomental distance in sniffing position

    In centimetres

    Time frame: 30 min before operation

  8. Thyrohyoid distance in sniffing position

    In centimetres

    Time frame: 30 min before operation

  9. Cricothyroid distance in sniffing position

    In centimetres

    Time frame: 30 minutes before operation

  10. Anterior soft tissue thickness at level of hyoid bone in sniffing position

    In centimetres

    Time frame: 30 min before operation

  11. Anterior soft tissue thickness at level of epiglottis in sniffing position

    In centimetres

    Time frame: 30 min before operation

  12. Anterior soft tissue thickness at level of vocal cord in sniffing position

    In centimetres

    Time frame: 30 min before operation

Other outcomes

  1. Age

    Years

    Time frame: 30 min before operation

07

Study locations

1 site
  • Cairo University
    Cairo, Cairo Governorate 12613, Egypt
08

References and documents

Publications

  • Parameswari A, Govind M, Vakamudi M. Correlation between preoperative ultrasonographic airway assessment and laryngoscopic view in adult patients: A prospective study. J Anaesthesiol Clin Pharmacol. 2017 Jul-Sep;33(3):353-358. doi: 10.4103/joacp.JOACP_166_17. PubMed 29109635 ↗
  • Roth D, Pace NL, Lee A, Hovhannisyan K, Warenits AM, Arrich J, Herkner H. Airway physical examination tests for detection of difficult airway management in apparently normal adult patients. Cochrane Database Syst Rev. 2018 May 15;5(5):CD008874. doi: 10.1002/14651858.CD008874.pub2. PubMed 29761867 ↗
  • Gomes SH, Simoes AM, Nunes AM, Pereira MV, Teoh WH, Costa PS, Kristensen MS, Teixeira PM, Pego JM. Useful Ultrasonographic Parameters to Predict Difficult Laryngoscopy and Difficult Tracheal Intubation-A Systematic Review and Meta-Analysis. Front Med (Lausanne). 2021 May 28;8:671658. doi: 10.3389/fmed.2021.671658. eCollection 2021. PubMed 34124099 ↗

Individual participant data

Plan to share: Yes

Supporting information: Study protocol

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 28, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06700265
Lead sponsor
National Cancer Institute, Egypt
Responsible party
Sponsor
First posted
Nov 21, 2024
Start date
Mar 20, 2023
Primary completion
Mar 1, 2026
Completion
Mar 1, 2026
Last update
Apr 28, 2026

Study contacts

ayman ali ghoneim, MD in anesthesia
study director · national cancer institute in egypt

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.

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