An interventional study of Manual manipulation and Sham manipulation in Sacroiliac Dysfunction, sponsored by Aveiro University. Completed at 1 site in Portugal. Open to participants aged 18 Years to 30 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-31.
Sponsored by Aveiro University · Not applicable, Interventional, and Treatment
The investigators will essentially have two main objectives:
To try to understand the immediate, global and immediate effect of ASI manipulation.
Initially, we will assess the participants with sacroiliac dysfunction. The experimental will be manipulated, the control group will do nothing, and the sham group will be submitted to a hypothetical manipulation (sham manipulation). Consequently, the patients will be assessed again, measuring the subjective and objective degree of pain and muscle tone.
- Material and methods
We will make use of:
Introduction
ASI dysfunction refers to a state of altered biomechanics of this joint . This dysfunction can result from repetitive stress , degeneration, lumbar deformities, inflammation, and previous lumbar fusion.
ASI dysfunction is an alteration in the normal biomechanics of the joint, which leads to hypomobility or hypermobility of that joint. It is one of the most common causes of misdiagnosis in low back pain and when not treated correctly, it often develops into chronic pain (30% to 42%) and disability.
The SIJ has a crucial function in mobility, stability and resistance against shear forces, and is also wrongly undervalued as the origin of low back pain and, with the increase in average life expectancy, it has become an extremely prevalent problem.
Manipulation of the SIJ in dysfunction appears to bring about benefits and significantly positive changes at various levels. The analysis of the results of two manipulative therapy techniques in patients with sacroiliac dysfunction revealed a statistically significant improvement immediately after treatment, after 48 hours and one month later, in terms of both pain and disability, as favourable developments were recorded in measurements using the VAS and the Oswestry Disability Index (ODI).
Even in asymptomatic individuals, there seem to be changes that are not just local, when manipulating the ASI, they came to the conclusion that the manipulation of the ASI applied bilaterally in asymptomatic people resulted in immediate changes in load distribution on the plantar support, in the orthostatic position, after baropodometric analysis using a force platform.
The benefits of this therapeutic approach were also defended, after a study in young females with SIJ dysfunction, subjected to a single SIJ manipulation session, in which the analysis of results after evaluation with EVA instruments and a digital algometer ( Model J- Tech ), indicate that the manipulation helped to alleviate the level of pain, with the effects lasting for 24 hours, immediately increasing the range of motion of internal and external rotations of the hips and lumbar flexion and extension.
Despite the existence of multiple studies on the benefits of this type of approach at various levels, in a more or less localized way, we did not find any study that showed correlated changes at a global level. With this work, we will seek to map the most evident symptomatological changes in the different regions of the human body associated with ASI dysfunction and evaluate the potential of manipulating the ASI in individuals with dysfunction of this joint, analyzing at specific points in the different segments, the initial state in terms of inequality of perceived pain and difference in muscle tone verified, measuring, following manipulation, the observable changes in these variables. As instruments for this assessment, we will use the following variables:
The main objective of this PhD thesis will be to understand the effect of manipulation on the dysfunction of the SIJD.
Objectives
Study Design and Methods
Study Design Experimental pilot study, where participants will be randomly allocated to experimental, control and sham groups. It will be carried out at the University of Aveiro facilities, with a sample of 21 students.
Participants The study sample will be a convenience sample, randomly selected from the universe of students at the University of Aveiro, invited to participate in the study.
Variables :
Instruments : -
Pressure Algometer , to assess pain, used at the following points:
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This study's enrollment of 21 is below the median of 70 across 1,911 interventional studies indexed under Pain.
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Exclusion Criteria:
Experimental group, subject to manipulation performed by the same Physiotherapist, using the techniques described by Shadmehr, A. et al (2018).
Other: Manual manipulation
Sham group, subjected only to a simulation of manipulation, using the same gestures, but without manipulating, used as a placebo group.
Other: Sham manipulation
Control group, which will not be subject to any intervention.
The participants will receive one session of manipulation if in the experimental group. It should be mentioned that the technique will be carried out by a physiotherapist with a history of more than 10 years of manual therapy. For instance, to correct right anterior innominate rotation, the participant will be made to lie on the side so that the affected side is upward. The physiotherapist will stand in front of the participant; first we will put their shoulders, pelvis and lower limbs in neutral position and place the right hand on the anterior superior iliac spine (ASIS) and the left hand on the ischium tuberosity and with a rotational movement of the hands, the physiotherapist will rotate the ilium posteriorly. At the end of the range, we will replace the position of hands and place the left forearm on the ischium tuberosity and place the right hand on the upper participant's shoulder and will move it toward the bed at the end of the range in exhalation a thrust will be executed.
The participants will receive one session of sham manipulation if in the sham group. For instance, to correct right anterior innominate rotation, the participant will be made to lie on the side so that the affected side is upward. The physiotherapist will stand in front of the participant; first we will put their shoulders, pelvis and lower limbs in neutral position and place the right hand on the anterior superior iliac spine (ASIS) and the left hand on the ischium tuberosity and with a rotational movement of the hands, the physiotherapist will rotate the ilium posteriorly. At the end of the range, we will replace the position of hands and place the left forearm on the ischium tuberosity and place the right hand on the upper participant's shoulder and will move it toward the bed at the end of the range in exhalation, the physiotherapist will pretend to execute a thrust.
Pain intensity assessed using the Visual Analogue Scale (VAS)
Pain intensity was assessed using a 10-cm Visual Analogue Scale (VAS), ranging from 0 (no pain) to 10 (worst pain).
Time frame: From enrollment the assessment will be executed, before and immediately after the intervention taking approximately one week
Passive muscle mechanical properties assessed using MyotonPRO
Passive muscle mechanical properties were assessed using the MyotonPRO, including muscle tone (frequency), stiffness, and logarithmic decrement.
Time frame: Immediately before and immediately after the intervention.
Pressure Pain Threshold (PPT) assessed using pressure algometry
Pressure pain threshold (PPT) was assessed using the Commander™ pressure algometer (JTECH Medical) at the predefined anatomical sites.
Time frame: Immediately before and immediately after the intervention.
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