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Not yet recruitingNCT06684353Updated Nov 15, 2024

Clinical Presentation and Outcome of COPD Patients With Acute Exacerbation Attending Sohag University Hospital

An observational study in Chronic Obstructive Pulmonary Disease, sponsored by Sohag University. Not yet recruiting. Open to participants aged 18 Years to 90 Years. Per ClinicalTrials.gov, last updated 2024-11-15.

Sponsored by Sohag University · Observational

From the registry’s dates

  • Primary completion was expected by Nov 2025, 11 months ago, but the record still lists the study as not yet recruiting.
Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
200
Ages
18 Years to 90 Years
Sex
All
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Study summary

Chronic obstructive pulmonary disease (COPD) is a worldwide public health challenge because of high prevalence and related disability and mortality (1).

Acute exacerbation of COPD (AECOPD), defned as the worsening of respiratory symptoms and requirement of additional clinical treatment, it reduces lung function and quality of life, and is accompanied by an increased disease-related burden, high hospital mortality and poor outcome (2).

Chronic obstructive pulmonary disease frequently coexists with other chronic diseases, namely comorbidities. They negatively impact prognosis, exacerbations and quality of life in COPD patients. Local and systemic inflammation have been proposed as having a potential role in explaining the association between COPD and these comorbidities (3).

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Conditions studied

  • Chronic Obstructive Pulmonary Disease
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In context

Pulmonary Disease, Chronic Obstructive

4,252 studies on the registry are indexed under Pulmonary Disease, Chronic Obstructive; 707 are open to participants now.

This study's planned enrollment of 200 is close to the median of 183 across 1,099 observational studies indexed under Pulmonary Disease, Chronic Obstructive.

Browse Pulmonary Disease, Chronic Obstructive studies →

Lead sponsor

Sohag University is the lead sponsor of 1,218 studies on the registry; 627 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 90 Years
Sexes eligible
All
Sampling method
Probability sample

Study population

patients aged more than 18 years with a confirmed COPD diagnosis according to (GOLD) guidelines, presented with acute exacerbation

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

patients with a confirmed COPD diagnosis according to (GOLD) guidelines, presented with acute exacerbation

Exclusion criteria

Exclusion Criteria:

  • Stable COPD
  • Any other chronic chest diseases; Bronchial asthma or bronchiectasis
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Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
200 participants (estimated)
Patient registry
No

Groups and cohorts

  • COPD patients in ICU with high risk of mortality (non survivors)

    COPD patients on NIV / MV

  • COPD patients in ICU with low risk of mortality ( survivors )

    COPD patients on NIV / MV

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What researchers measure

Primary outcomes

  1. Clinical Presentation and Outcome of COPD Patients With Acute Exacerbation Attending Sohag University Hospital

    Detection which patient with COPD exacerbation has more risk of survival or mortality

    Time frame: 1 year

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Study locations

No study locations are listed for this record.

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References and documents

Publications

  • Fabbri LM, Boschetto P, Mapp CE; Global Initiative for Chronic Obstructive Lung Disease; Global Initiative for Asthma Management and Prevention. COPD guidelines: the important thing is not to stop questioning. Am J Respir Crit Care Med. 2007 Sep 15;176(6):527-8. doi: 10.1164/rccm.200706-854ED. No abstract available. PubMed 17823358 ↗
  • Bateman ED, Feldman C, O'Brien J, Plit M, Joubert JR; COPD Guideline Working Group of the South African Thoracic Society. Guideline for the management of chronic obstructive pulmonary disease (COPD): 2004 revision. S Afr Med J. 2004 Jul;94(7 Pt 2):559-75. PubMed 15283307 ↗
  • Corrections. Lancet Respir Med. 2017 Oct;5(10):e30. doi: 10.1016/S2213-2600(17)30336-3. Epub 2017 Sep 14. No abstract available. PubMed 28918970 ↗
  • Nakai T, Ueda M, Takeda R. Effects of calcium and magnesium ions on the interaction of corticosterone with rat brain cytosol receptor(s). Endocr Res Commun. 1978;5(2):81-90. doi: 10.3109/07435807809089010. PubMed 102509 ↗
  • Hand D. National Boards lose control of funding. Nurs Stand. 1991 Feb 13-19;5(21):20. No abstract available. PubMed 1900164 ↗

Individual participant data

Plan to share: Undecided

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 15, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06684353
Lead sponsor
Sohag University
Responsible party
Mona Abdelaleem Hussien (Resident doctor at chest department Sohag University Hospital, Sohag University) — Principal investigator
First posted
Nov 12, 2024
Start date
Nov 30, 2024 (estimated)
Primary completion
Nov 3, 2025 (estimated)
Completion
Nov 3, 2025 (estimated)
Last update
Nov 15, 2024

Study contacts

Mona A Hussien, Resident doctor
Contact
mona_abdelaleem_post@med.sohag.edu.eg
01152232471
Hamdy A Mohammaden, Professor doctor
Contact

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Oct 2024. You cannot join it, but the record below documents what was studied.

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Discussion

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