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CompletedNCT06677281COVID-PREGUpdated Nov 6, 2024

Impact of COVID-19 on Pregnancy Outcomes: a Systematic Review

An observational study in COVID-19, Pregnancy Outcomes and Maternal Health, sponsored by Zahedan University of Medical Sciences. Completed at 1 site in Iran, Islamic Republic of. Open to female participants. Per ClinicalTrials.gov, last updated 2024-11-06.

Sponsored by Zahedan University of Medical Sciences · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
1
Sex
Female
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Study summary

This systematic review aims to evaluate the impact of COVID-19 on pregnancy outcomes. It synthesizes data from various studies to provide insights into the effects of the virus on maternal and fetal health. The review focuses on key outcomes such as preterm birth, maternal complications, and neonatal health, utilizing comprehensive literature from peer-reviewed journals. By analyzing existing studies, we aim to identify trends and gaps in research regarding COVID-19 and pregnancy. This review is intended to inform healthcare providers and pregnant individuals about potential risks and considerations during the pandemic.

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Conditions studied

  • COVID-19
  • Pregnancy Outcomes
  • Maternal Health
  • Neonatal Health

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In context

COVID-19

7,990 studies on the registry are indexed under COVID-19; 466 are open to participants now.

This study's enrollment of 1 is below the median of 268 across 3,208 observational studies indexed under COVID-19.

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Lead sponsor

Zahedan University of Medical Sciences is the lead sponsor of 15 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
Female
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

The study population consists of pregnant individuals diagnosed with COVID-19 as documented in various peer-reviewed studies. The review examines the impact of COVID-19 on pregnancy outcomes, including maternal health, delivery outcomes, and neonatal complications.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Pregnant individuals diagnosed with COVID-19.
  • Studies reporting pregnancy outcomes related to COVID-19 published between January 2020 and the present.
  • Articles that include quantitative data on maternal and fetal outcomes.

Exclusion criteria

Exclusion Criteria:

  • Studies that do not report on COVID-19-related pregnancy outcomes.
  • Non-peer-reviewed articles or grey literature.
  • Research focusing on non-pregnant populations.
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
1 participant (actual)
Patient registry
No

Interventions

  • OtherSystematic Review of COVID-19's Impact on Pregnancy Outcomes

    This study is a systematic review of existing literature that examines the effects of COVID-19 on pregnancy outcomes, including maternal health, neonatal health, and obstetric complications. It synthesizes data from various studies to provide an overview of the potential risks associated with COVID-19 infection during pregnancy. This intervention does not involve any new clinical trials or direct patient interaction.

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What researchers measure

Primary outcomes

  1. Impact of COVID-19 on Maternal and Neonatal Outcomes

    This primary outcome measure evaluates the various maternal and neonatal outcomes associated with COVID-19 infection during pregnancy. Key metrics include rates of maternal morbidity, neonatal morbidity, preterm birth, low birth weight, and any documented complications during pregnancy, labor, and delivery. The systematic review aims to synthesize data from available studies to provide a comprehensive understanding of these outcomes and their implications for clinical practice.

    Time frame: The review encompasses studies published from January 2020 to the present, with a focus on maternal and neonatal outcomes reported within the specified time frame.

Secondary outcomes

  1. Effects of COVID-19 on Pregnancy-Related Complications

    This secondary outcome measure assesses the frequency and types of pregnancy-related complications associated with COVID-19. This includes conditions such as gestational hypertension, gestational diabetes, placental abruption, and other adverse effects that may arise during the pregnancy period. The review aims to analyze the incidence of these complications in pregnant individuals diagnosed with COVID-19 compared to non-infected counterparts, providing insights into how the virus may impact overall pregnancy health.

    Time frame: The review includes data from studies published between January 2020 and the present, focusing on complications reported throughout the pregnancy and at delivery.

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Study locations

1 site
  • Zahedan University of Medical Sciences
    Zahedan, Sistan and Baluchestan, Iran, Islamic Republic of
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 6, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06677281
Lead sponsor
Zahedan University of Medical Sciences
Responsible party
Hamidreza Kouhpayeh (Assistant professor, Zahedan University of Medical Sciences) — Principal investigator
First posted
Nov 6, 2024
Start date
May 3, 2024
Primary completion
Aug 15, 2024
Completion
Aug 25, 2024
Last update
Nov 6, 2024

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2024. You cannot join it, but the record below documents what was studied.

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