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Enrolling by invitationNCT06657651Updated Oct 28, 2024

IMMEDIATE IMPLANT With Different Types of Membranes

An interventional study of immediate implant placement with dentin-derived membrane and immediate implant with extended platelet rich fibrin membrane in Tooth Extraction, sponsored by Mansoura University. Enrolling by invitation at 1 site in Egypt. Open to participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-10-28.

Sponsored by Mansoura University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Mar 2025, 1 year 7 months ago, but the record still lists the study as enrolling by invitation.
  • Registered 3 months after the study started (first participant enrolled Jun 2024, registered Oct 2024).
Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Randomized
Ages
18 Years to 60 Years
Sex
All
01

Study summary

forty patients will be selected from the outpatient's clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University for replacement of non-restorable tooth in posterior mandibular area.

Patients' Grouping:

The patients will be randomly divided into two equal uniform groups each consists of 20 patients:

Group A:

20 patients with non-restorable mandibular molar tooth will be treated with an immediately placed dental implant in conjunction with a dentin-derived membrane from the extracted tooth.

Group B:

20 patients with non-restorable mandibular molar tooth will be treated with an immediately placed dental implant in conjunction with extended platelet rich fibrin membrane.

02

Conditions studied

  • Tooth Extraction
03

In context

Lead sponsor

Mansoura University is the lead sponsor of 1,077 studies on the registry; 183 are open to participants now.

Of its 9 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Age above 18 years
  • Non-restorable mandibular molar tooth that needs dental extraction \& guided bone regeneration for immediate implant placement.
  • Acceptable inter-arch space for the future prosthesis.
  • Patient medically free from systemic diseases that absolutely contraindicate implant surgery.
  • Cooperative patient with high motivation and acceptable oral hygiene.
  • Free from history of bruxism / parafunctional habits.

Exclusion criteria

Exclusion Criteria:

  • Local and / or systemic conditions that interfere with the procedure.
  • Smokers.
  • Pregnancy.
  • Uncooperative patients.
  • Patient had undergone in the past 12 months radiation therapy to the head and neck area.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Triple (Participant, Investigator, Outcomes assessor)
Enrollment
40 participants (estimated)

Study arms

  • Experimental
    immediate implant with dentin-derived membrane

    Procedure: immediate implant placement with dentin-derived membrane

  • Experimental
    immediate implant with extended platelet rich fibrin membrane

    Procedure: immediate implant with extended platelet rich fibrin membrane

Interventions

  • Procedureimmediate implant placement with dentin-derived membrane

    immediate implant placement with dentin-derived membrane and allograft in mandibular molar area

  • Procedureimmediate implant with extended platelet rich fibrin membrane

    immediate implant with extended platelet rich fibrin membrane and allograft in mandibular molar area

06

What researchers measure

Primary outcomes

  1. Implant stability

    Osstell will be used to record implant stability at the placement time, 3, 6 and 12 months after surgery.

    Time frame: 1 year

07

Study locations

1 site
  • Heba Elsheikh
    Mansoura, Egypt
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 28, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06657651
Lead sponsor
Mansoura University
Responsible party
Sponsor
First posted
Oct 24, 2024
Start date
Jun 30, 2024
Primary completion
Mar 1, 2025 (estimated)
Completion
Jun 1, 2025 (estimated)
Last update
Oct 28, 2024

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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No contact was published for this record. The registry link below has the sponsor’s details.

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